Drug Description in Trials / DrugBank / KEGG DRUG

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No.

薬物名（臨床試験情報から抽出）

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

指定難病告示番号

1

Experimental: Seladelpar / MBX-8025 200 mg

1件: Seladelpar

1件: Seladelpar 💬

1件: PPARG 💬

11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬

1件: 93 💬

2

Experimental: Seladelpar / MBX-8025 50 mg

1件: Seladelpar

1件: Seladelpar 💬

1件: PPARG 💬

11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬

1件: 93 💬

3

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3件: 79, 93, 94 💬

告示番号	日本語名	英語名
79	家族性高コレステロール血症（ホモ接合体）	Homozygous familial hypercholesterolemia
93	原発性胆汁性胆管炎	Primary biliary cholangitis
94	原発性硬化性胆管炎	Primary sclerosing cholangitis

4

MBX-8025 50 mg (Dose Escalation Period 1)

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-

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-

1件: 79 💬

5

MBX-8025 50 mg or 100 mg (Dose Escalation Period 2)

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-

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-

1件: 79 💬

6

MBX-8025 50 mg, 100 mg or 200 mg (Dose Escalation Period 3)

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-

1件: 79 💬

7

-

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-

1件: 93 💬

8

MBX-8025, Formulation 2

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-

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-

1件: 93 💬