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Showing 1 to 4 of 4 descriptions
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No.
薬物名(臨床試験情報から抽出)
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Abatacept (ABA) +
Methotrexate (MTX)
, double-blind (DB)
2件:
Abatacept
Abatacept
,
Methotrexate
2件:
D00142
D00142
,
D03203
4件:
CD80
CD80
,
CD86
,
DHFR
,
DHFR2
💬
18件:
Allograft rejection
Allograft rejection
,
Antifolate resistance
,
Autoimmune thyroid disease
,
Biosynthesis of cofactors
,
Cell adhesion molecules
,
Folate biosynthesis
,
Graft-versus-host disease
,
Intestinal immune network for IgA production
,
Kaposi sarcoma-associated herpesvirus infection
,
Metabolic pathways
,
One carbon pool by folate
,
Rheumatoid arthritis
,
Systemic lupus erythematosus
,
Toll-like receptor signaling pathway
,
Transcriptional misregulation in cancer
,
Type I diabetes mellitus
,
Viral myocarditis
,
Virion - Adenovirus
💬
18件:
Allograft rejection
,
Antifolate resistance
,
Autoimmune thyroid disease
,
Biosynthesis of cofacto
...
1件:
46
46
2
Certolizumab Pegol +
Methotrexate (MTX)
2件:
Certolizumab pegol
Certolizumab pegol
,
Methotrexate
2件:
D00142
D00142
,
D03441
3件:
DHFR
DHFR
,
DHFR2
,
TNF
💬
71件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African trypanosomiasis
,
Alcoholic liver disease
,
Allograft rejection
,
Alzheimer disease
,
Amoebiasis
,
Amyotrophic lateral sclerosis
,
Antifolate resistance
,
Antigen processing and presentation
,
Apoptosis
,
Asthma
,
Biosynthesis of cofactors
,
C-type lectin receptor signaling pathway
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Dilated cardiomyopathy
,
Epstein-Barr virus infection
,
Fc epsilon RI signaling pathway
,
Fluid shear stress and atherosclerosis
,
Folate biosynthesis
,
Graft-versus-host disease
,
Hematopoietic cell lineage
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Influenza A
,
Insulin resistance
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
One carbon pool by folate
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Prion disease
,
Proteoglycans in cancer
,
RIG-I-like receptor signaling pathway
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
Sphingolipid signaling pathway
,
Systemic lupus erythematosus
,
T cell receptor signaling pathway
,
TGF-beta signaling pathway
,
TNF signaling pathway
,
Toll-like receptor signaling pathway
,
Toxoplasmosis
,
Tuberculosis
,
Type I diabetes mellitus
,
Type II diabetes mellitus
,
Viral protein interaction with cytokine and cytokine receptor
,
Yersinia infection
,
mTOR signaling pathway
💬
71件:
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African
...
1件:
46
46
3
Infliximab +
methotrexate (MTX)
2件:
Infliximab
Infliximab
,
Methotrexate
2件:
D00142
D00142
,
D02598
3件:
DHFR
DHFR
,
DHFR2
,
TNF
💬
71件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African trypanosomiasis
,
Alcoholic liver disease
,
Allograft rejection
,
Alzheimer disease
,
Amoebiasis
,
Amyotrophic lateral sclerosis
,
Antifolate resistance
,
Antigen processing and presentation
,
Apoptosis
,
Asthma
,
Biosynthesis of cofactors
,
C-type lectin receptor signaling pathway
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Dilated cardiomyopathy
,
Epstein-Barr virus infection
,
Fc epsilon RI signaling pathway
,
Fluid shear stress and atherosclerosis
,
Folate biosynthesis
,
Graft-versus-host disease
,
Hematopoietic cell lineage
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Influenza A
,
Insulin resistance
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
One carbon pool by folate
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Prion disease
,
Proteoglycans in cancer
,
RIG-I-like receptor signaling pathway
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
Sphingolipid signaling pathway
,
Systemic lupus erythematosus
,
T cell receptor signaling pathway
,
TGF-beta signaling pathway
,
TNF signaling pathway
,
Toll-like receptor signaling pathway
,
Toxoplasmosis
,
Tuberculosis
,
Type I diabetes mellitus
,
Type II diabetes mellitus
,
Viral protein interaction with cytokine and cytokine receptor
,
Yersinia infection
,
mTOR signaling pathway
💬
71件:
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African
...
1件:
46
46
4
Methotrexate (MTX)
1件:
Methotrexate
Methotrexate
1件:
D00142
D00142
2件:
DHFR
DHFR
,
DHFR2
💬
5件:
Antifolate resistance
Antifolate resistance
,
Biosynthesis of cofactors
,
Folate biosynthesis
,
Metabolic pathways
,
One carbon pool by folate
💬
5件:
Antifolate resistance
,
Biosynthesis of cofactors
,
Folate biosynthesis
,
Metabolic pathways
,
One c
...
1件:
46
46