Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Administration of Methylprednisolone + Prednisone + Mycophenolate mofetil4件: Methylprednisolone,
Mycophenolate mofetil,
Mycophenolic acid,
Prednisone		4件: D00407 (Name: Methylprednisolone),
D00473 ,
D00752 ,
D05096 		3件: IMPDH1,
IMPDH2,
NR3C1 💬		5件: Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Nucleotide metabolism, Purine metabolism 💬1件: 49
2Administration of methylprednisolone, paracetamol and dexchlorpheniramine3件: Acetaminophen,
Dexchlorpheniramine,
Methylprednisolone		3件: D00217 ,
D00407 (Name: Methylprednisolone),
D07803 		4件: HRH1,
NR3C1,
PTGS1,
PTGS2 💬		26件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Calcium signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 49
3Administration of rituximab and methylprednisolone2件: Methylprednisolone,
Rituximab		2件: D00407 (Name: Methylprednisolone),
D02994 		2件: MS4A1,
NR3C1 💬		2件: Hematopoietic cell lineage, Neuroactive ligand-receptor interaction 💬1件: 51
4Corticosteroid treatment (Methylprednisolone or prednisolone)2件: Methylprednisolone,
Prednisolone		2件: D00407 (Name: Methylprednisolone),
D00472 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 64
5Cyclophosphamide, Azathioprine,prednisone,methylprednisolone4件: Azathioprine,
Cyclophosphamide,
Methylprednisolone,
Prednisone		5件: D00238 ,
D00287 ,
D00407 (Name: Methylprednisolone),
D00473 ,
D07760 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 42, 43, 45
6Infliximab, methylprednisolone, methotrexate3件: Infliximab,
Methotrexate,
Methylprednisolone		3件: D00142 ,
D00407 (Name: Methylprednisolone),
D02598 		4件: DHFR,
DHFR2,
NR3C1,
TNF 💬		72件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46
7Interferon-beta-1a (Avonex) plus methylprednisolone3件: Human interferon beta,
Interferon beta-1a,
Methylprednisolone		2件: D00407 (Name: Methylprednisolone),
D04554 		3件: IFNAR1,
IFNAR2,
NR3C1 💬		19件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 13
8Intravenous (i.v.) methylprednisolone 1000 mg, total 91件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 222
9Intravenous Methylprednisolone1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 13, 145
10IV methylprednisolone1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
11IV methylprednisolone (steroids)1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
12Megadose oral methylprednisolone1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
13Methotrexate + Methylprednisolone2件: Methotrexate,
Methylprednisolone		2件: D00142 ,
D00407 (Name: Methylprednisolone)		3件: DHFR,
DHFR2,
NR3C1 💬		6件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Neuroactive ligand-receptor interaction, One carbon pool by folate 💬1件: 46
14Methylprednisolone1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
15Methylprednisolone (drug)1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
16Methylprednisolone (MP)1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 60, 285
17Methylprednisolone (MP) or prednisone (pred)2件: Methylprednisolone,
Prednisone		2件: D00407 (Name: Methylprednisolone),
D00473 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 66
18Methylprednisolone (or other glucocorticoid)1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 43
19Methylprednisolone (Solu-Medrol)1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 14
20Methylprednisolone 1250 mg/24h x3 days1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
21METHYLPREDNISOLONE ACETATE2件: Acetate,
Methylprednisolone		1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 46, 51
22Methylprednisolone and azathioprine2件: Azathioprine,
Methylprednisolone		2件: D00238 ,
D00407 (Name: Methylprednisolone)		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 93, 95
23Methylprednisolone and Mycophenolate mofetil3件: Methylprednisolone,
Mycophenolate mofetil,
Mycophenolic acid		3件: D00407 (Name: Methylprednisolone),
D00752 ,
D05096 		3件: IMPDH1,
IMPDH2,
NR3C1 💬		5件: Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Nucleotide metabolism, Purine metabolism 💬2件: 93, 95
24Methylprednisolone bolus IV 15 mg/kg/d for 3 days.1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 84
25Methylprednisolone hemisuccinate2件: Methylprednisolone,
Methylprednisolone hemisuccinate		2件: D00407 (Name: Methylprednisolone),
D05000 (Name: Methylprednisolone hemisuccinate)		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
26Methylprednisolone IV1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
27METHYLPREDNISOLONE MYLAN Générique1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 66
28Methylprednisolone or budesonide2件: Budesonide,
Methylprednisolone		2件: D00246 ,
D00407 (Name: Methylprednisolone)		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 96
29Methylprednisolone or Prednisolone2件: Methylprednisolone,
Prednisolone		2件: D00407 (Name: Methylprednisolone),
D00472 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 65
30Methylprednisolone PO1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
31Methylprednisolone pulse1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 66, 220
32METHYLPREDNISOLONE SODIUM HEMISUCCINATE1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 13, 97
33METHYLPREDNISOLONE SODIUM SUCCINATE1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬6件: 13, 46, 49, 50, 51, 211
34Methylprednisolone succinate2件: Methylprednisolone,
Methylprednisolone hemisuccinate		2件: D00407 (Name: Methylprednisolone),
D05000 (Name: Methylprednisolone hemisuccinate)		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
35Methylprednisolone(intravenously in the 1st-2nd-3rd month )1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 66
36Methylprednisolone(intravenously in the 1st-3rd-5th month)1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 66
37Oral 5-ASA+/-topical 5-ASA+IV corticosteroids / PO Methylprednisolone2件: Mesalazine,
Methylprednisolone		2件: D00377 ,
D00407 (Name: Methylprednisolone)		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
38Oral Methylprednisolone 625 mg/24h x3 days1件: Methylprednisolone1件: D00407 (Name: Methylprednisolone)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
39Prednisone (and methylprednisolone)2件: Methylprednisolone,
Prednisone		2件: D00407 (Name: Methylprednisolone),
D00473 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 43
40Prednisone, methylprednisolone,cyclophosphamides2件: Methylprednisolone,
Prednisone		2件: D00407 (Name: Methylprednisolone),
D00473 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 42, 43, 45
41Ursodeoxycholic acid+Low Dose Glucocorticoid(Methylprednisolone)2件: Methylprednisolone,
Ursodeoxycholic acid		2件: D00407 (Name: Methylprednisolone),
D00734 		2件: NR1H4,
NR3C1 💬		2件: Bile secretion, Neuroactive ligand-receptor interaction 💬1件: 93