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Target Gene/Pathway
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Showing 1 to 10 of 10 descriptions
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No.
薬物名(臨床試験情報から抽出)
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Biological: Benralizumab, Biological: Placebo to Mepolizumab
(Synonym:
Nucala
(TN))
2件:
Benralizumab
Benralizumab
,
Mepolizumab
(Synonym:
Nucala
)
2件:
D04923
D04923
(Name:
Nucala
(TN))
,
D09874
2件:
IL5
IL5
,
IL5RA
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
1件:
44
44
2
Biological: Mepolizumab, Biological: Placebo to Benralizumab
(Synonym:
Nucala
(TN))
2件:
Benralizumab
Benralizumab
,
Mepolizumab
(Synonym:
Nucala
)
2件:
D04923
D04923
(Name:
Nucala
(TN))
,
D09874
2件:
IL5
IL5
,
IL5RA
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
1件:
44
44
3
MEPOLIZUMAB
(Synonym:
Nucala
(TN))
1件:
Mepolizumab
Mepolizumab
(Synonym:
Nucala
)
1件:
D04923
D04923
(Name:
Nucala
(TN))
1件:
IL5
IL5
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
4件:
44
44
,
45
,
98
,
162
4
Mepolizumab (a-IL-5 antibody)
(Synonym:
Nucala
(TN))
1件:
Mepolizumab
Mepolizumab
(Synonym:
Nucala
)
1件:
D04923
D04923
(Name:
Nucala
(TN))
1件:
IL5
IL5
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
1件:
162
162
5
Mepolizumab 100 mg
(Synonym:
Nucala
(TN))
1件:
Mepolizumab
Mepolizumab
(Synonym:
Nucala
)
1件:
D04923
D04923
(Name:
Nucala
(TN))
1件:
IL5
IL5
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
1件:
98
98
6
Mepolizumab 300 mg
(Synonym:
Nucala
(TN))
1件:
Mepolizumab
Mepolizumab
(Synonym:
Nucala
)
1件:
D04923
D04923
(Name:
Nucala
(TN))
1件:
IL5
IL5
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
1件:
98
98
7
NUCALA
1件:
Mepolizumab
Mepolizumab
(Synonym:
Nucala
)
1件:
D04923
D04923
(Name:
Nucala
(TN))
1件:
IL5
IL5
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
2件:
44
44
,
45
8
Nucala
100 mg powder for solution for injection
1件:
Mepolizumab
Mepolizumab
(Synonym:
Nucala
)
1件:
D04923
D04923
(Name:
Nucala
(TN))
1件:
IL5
IL5
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
2件:
44
44
,
45
9
NUCALA
®
1件:
Mepolizumab
Mepolizumab
(Synonym:
Nucala
)
1件:
D04923
D04923
(Name:
Nucala
(TN))
1件:
IL5
IL5
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
1件:
44
44
10
SB-240563 (mepolizumab)
(Synonym:
Nucala
(TN))
1件:
Mepolizumab
Mepolizumab
(Synonym:
Nucala
)
1件:
D04923
D04923
(Name:
Nucala
(TN))
1件:
IL5
IL5
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
2件:
44
44
,
45