Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1100 mg ELX (VX-445) / 50 mg TEZ / 75 mg IVA FDC----1件: 299
2100 mg ELX /50 mg TEZ /75 mg IVA FDC----1件: 299
3100 mg ELX/50 mg TEZ /75 mg IVA FDC----1件: 299
4100 mg ELX/50 mg TEZ/75 mg IVA fixed dose combination----1件: 299
5100 mg TEZ/150 mg IVA FDC----1件: 299
6100 mg VX-445 /50 mg TEZ/75 mg IVA FDC----1件: 299
7100 mg VX-445/50 mg TEZ /75 mg IVA FDC----1件: 299
8100-mg ELX (VX-445) / 50-mg TEZ / 75-mg IVA FDC----1件: 299
9100-mg ELX (VX-455) / 50-mg TEZ / 75-mg IVA FDC----1件: 299
10100-mg ELX / 50-mg TEZ / 75 -mg IVA FDC----1件: 299
11100-mg VX-445 / 50-mg TEZ / 75- mg IVA FDC----1件: 299
12100-mg VX-445 / 50-mg TEZ / 75-mg IVA FDC----1件: 299
13100-mg VX-445 /50-mg TEZ/75-mg----1件: 299
14100-mg VX-445/50-mg TEZ/75-mg IVA FDC----1件: 299
15100g ELX / 50mg TEZ / 75mg IVA----1件: 299
16100mg ELX/50mg TEZ /75mg IVA----1件: 299
17100mg VX-445/50mg TEZ /75mg IVA FDC----1件: 299
1850 mg ELX/25 mg TEZ/37.5 mg IVA----1件: 299
1950 mg ELX/25 mg TEZ/37.5 mg IVA fixed dose combination----1件: 299
2080mg ELX / 40mg TEZ / 60mg IVA----1件: 299
21Elexacaftor / Ivacaftor / Tezacaftor3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 ,
D11041 (Name: Tezacaftor),
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
22Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 ,
D11041 (Name: Tezacaftor),
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
23Elexacaftor-tezacaftor-ivacaftor exposure3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 ,
D11041 (Name: Tezacaftor),
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
24Elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 ,
D11041 (Name: Tezacaftor),
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
25ELX (VX-445)/TEZ (VX-661)/IVA (VX-770)----1件: 299
26ELX/TEZ/IVA----1件: 299
27Ivacaftor or elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 ,
D11041 (Name: Tezacaftor),
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
28TEZ----1件: 299
29TEZ/IVA----1件: 299
30TEZACAFTOR1件: Tezacaftor1件: D11041 (Name: Tezacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
31Tezacaftor (TEZ)1件: Tezacaftor1件: D11041 (Name: Tezacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
32Tezacaftor/Ivacaftor2件: Ivacaftor,
Tezacaftor		2件: D09916 ,
D11041 (Name: Tezacaftor)		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
33Tezacaftor/Ivacaftor + Ivacaftor2件: Ivacaftor,
Tezacaftor		2件: D09916 ,
D11041 (Name: Tezacaftor)		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
34Tezacaftor/Ivacaftor 100mg/150mg2件: Ivacaftor,
Tezacaftor		2件: D09916 ,
D11041 (Name: Tezacaftor)		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
35Tezacaftor/Ivacaftor/100mg/150mg2件: Ivacaftor,
Tezacaftor		2件: D09916 ,
D11041 (Name: Tezacaftor)		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
36Tezepelumab1件: Tezepelumab1件: D11771 (Name: Tezepelumab)1件: TSLP 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬1件: 98
37Tezepelumab via APFS1件: Tezepelumab1件: D11771 (Name: Tezepelumab)1件: TSLP 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬1件: 98
38Tezosentan1件: Tezosentan---1件: 86
39Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor4件: Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor		4件: D09916 ,
D10134 ,
D11041 (Name: Tezacaftor),
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
40VX-121/TEZ/D-IVA----1件: 299
41VX-121/tezacaftor/deutivacaftor2件: Deutivacaftor,
Tezacaftor		2件: D11041 (Name: Tezacaftor),
D11423 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
42VX-445 / TEZ / IVA----1件: 299
43VX-445 / TEZ / IVA FDC----1件: 299
44VX-445 /TEZ/IVA----1件: 299
45VX-445/TEZ/IVA----1件: 299
46VX-659/ TEZ/IVA1件: VX-659---1件: 299
47VX-659/TEZ/IVA1件: VX-659---1件: 299
48VX-659/Tezacaftor/Ivacaftor3件: Ivacaftor,
Tezacaftor,
VX-659		2件: D09916 ,
D11041 (Name: Tezacaftor)		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
49VX-661/VX-770 (TEZ/IVA)----1件: 299