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Showing 1 to 10 of 11 drugs
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KEGG DRUG
DrugBank
薬物名(臨床試験情報から抽出)
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Lamotrigine
1件:
Lamotrigine
Lamotrigine
2件:
Lamictal
Lamictal
;
Lamotrigine
;
5件:
SCN1A
SCN1A
,
SCN2A
,
SCN3A
,
SCN5A
,
SCN9A
💬
3件:
Adrenergic signaling in cardiomyocytes
Adrenergic signaling in cardiomyocytes
,
Dopaminergic synapse
,
Taste transduction
💬
5件:
13
13
,
34
,
38
,
114
,
144
2
Topiramate
1件:
Topiramate
Topiramate
2件:
TOPAMAX
TOPAMAX
;
Topiramate
;
36件:
CA2
CA2
,
CA4
,
CACNA1C
,
CACNA1D
,
CACNA1F
,
CACNA1S
,
GABRA1
,
GABRA2
,
GABRA3
,
GABRA4
,
GABRA5
,
GABRA6
,
GABRB1
,
GABRB2
,
GABRB3
,
GABRD
,
GABRE
,
GABRG1
,
GABRG2
,
GABRG3
,
GABRP
,
GABRQ
,
GRIA1
,
GRIA2
,
GRIA3
,
GRIA4
,
GRIK1
,
GRIK2
,
GRIK3
,
GRIK4
,
GRIK5
,
SCN1A
,
SCN2A
,
SCN3A
,
SCN5A
,
SCN9A
💬
36件:
CA2
,
CA4
,
CACNA1C
,
CACNA1D
,
CACNA1F
,
CACNA1S
,
GABRA1
,
GABRA2
,
GABRA3
,
GABRA4
,
GABRA5
,
GABRA6
,
GABRB1
,
GABRB2
...
53件:
Adrenergic signaling in cardiomyocytes
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secretion
,
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Arrhythmogenic right ventricular cardiomyopathy
,
Bile secretion
,
Calcium signaling pathway
,
Carbohydrate digestion and absorption
,
Cardiac muscle contraction
,
Cellular senescence
,
Chemical carcinogenesis - receptor activation
,
Cholinergic synapse
,
Circadian entrainment
,
Cocaine addiction
,
Collecting duct acid secretion
,
Cortisol synthesis and secretion
,
Cushing syndrome
,
Dilated cardiomyopathy
,
Dopaminergic synapse
,
GABAergic synapse
,
Gastric acid secretion
,
Glutamatergic synapse
,
GnRH secretion
,
GnRH signaling pathway
,
Growth hormone synthesis, secretion and action
,
Huntington disease
,
Hypertrophic cardiomyopathy
,
Insulin secretion
,
Long-term depression
,
Long-term potentiation
,
MAPK signaling pathway
,
Metabolic pathways
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Nicotine addiction
,
Nitrogen metabolism
,
Oxytocin signaling pathway
,
Pancreatic secretion
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Proximal tubule bicarbonate reclamation
,
Renin secretion
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Spinocerebellar ataxia
,
Taste transduction
,
Tight junction
,
Transcriptional misregulation in cancer
,
Type II diabetes mellitus
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
53件:
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secretion
,
Alzheimer disease
, ...
6件:
6
6
,
97
,
140
,
144
,
156
,
193
3
Clobazam
1件:
Clobazam
Clobazam
1件:
CLOBAZAM
CLOBAZAM
;
16件:
GABRA1
GABRA1
,
GABRA2
,
GABRA3
,
GABRA4
,
GABRA5
,
GABRA6
,
GABRB1
,
GABRB2
,
GABRB3
,
GABRD
,
GABRE
,
GABRG1
,
GABRG2
,
GABRG3
,
GABRP
,
GABRQ
💬
16件:
GABRA1
,
GABRA2
,
GABRA3
,
GABRA4
,
GABRA5
,
GABRA6
,
GABRB1
,
GABRB2
,
GABRB3
,
GABRD
,
GABRE
,
GABRG1
,
GABRG2
,
GABRG3
...
7件:
GABAergic synapse
GABAergic synapse
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Nicotine addiction
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Taste transduction
💬
7件:
GABAergic synapse
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Nicotine addicti
...
2件:
140
140
,
144
4
Polyethylene glycol 3350
1件:
Polyethylene glycol
Polyethylene glycol
4件:
Macrogol
Macrogol
;
Macrogol 4000
;
Polyethylene glycol
;
Polyethylene Glycol 3350
;
-
-
17件:
6
6
,
13
,
41
,
46
,
60
,
65
,
78
,
96
,
97
,
140
,
144
,
235
,
240
,
246
,
276
,
299
,
337
5
Rufinamide
1件:
Rufinamide
Rufinamide
2件:
Inovelon
Inovelon
;
RUFINAMIDE
;
5件:
SCN1A
SCN1A
,
SCN2A
,
SCN3A
,
SCN5A
,
SCN9A
💬
3件:
Adrenergic signaling in cardiomyocytes
Adrenergic signaling in cardiomyocytes
,
Dopaminergic synapse
,
Taste transduction
💬
1件:
144
144
6
Carisbamate
1件:
Carisbamate
Carisbamate
1件:
Carisbamate
Carisbamate
;
-
-
1件:
144
144
7
Fenfluramine
1件:
Fenfluramine
Fenfluramine
2件:
Fenfluramina
Fenfluramina
;
Fenfluramine
;
5件:
HTR1D
HTR1D
,
HTR2A
,
HTR2C
,
SIGMAR1
,
SLC6A4
💬
10件:
Amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis
,
Calcium signaling pathway
,
Gap junction
,
Inflammatory mediator regulation of TRP channels
,
Neuroactive ligand-receptor interaction
,
Pathways of neurodegeneration - multiple diseases
,
Serotonergic synapse
,
Synaptic vesicle cycle
,
Taste transduction
,
cAMP signaling pathway
💬
10件:
Amyotrophic lateral sclerosis
,
Calcium signaling pathway
,
Gap junction
,
Inflammatory mediator r
...
4件:
140
140
,
144
,
145
,
149
8
Perampanel
1件:
Perampanel
Perampanel
2件:
Fycompa
Fycompa
;
Perampanel
;
4件:
GRIA1
GRIA1
,
GRIA2
,
GRIA3
,
GRIA4
💬
16件:
Amphetamine addiction
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Circadian entrainment
,
Cocaine addiction
,
Dopaminergic synapse
,
Glutamatergic synapse
,
Huntington disease
,
Long-term depression
,
Long-term potentiation
,
Neuroactive ligand-receptor interaction
,
Nicotine addiction
,
Pathways of neurodegeneration - multiple diseases
,
Retrograde endocannabinoid signaling
,
Spinocerebellar ataxia
,
Transcriptional misregulation in cancer
,
cAMP signaling pathway
💬
16件:
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Circadian entrainment
,
Cocaine addiction
, ...
3件:
2
2
,
6
,
144
9
Ezogabine
1件:
Ezogabine
Ezogabine
4件:
Ezogabine
Ezogabine
;
Potiga
;
RETIGABINE
;
Trobalt
;
5件:
KCNQ1
KCNQ1
,
KCNQ2
,
KCNQ3
,
KCNQ4
,
KCNQ5
💬
6件:
Adrenergic signaling in cardiomyocytes
Adrenergic signaling in cardiomyocytes
,
Cholinergic synapse
,
Gastric acid secretion
,
Pancreatic secretion
,
Protein digestion and absorption
,
Vibrio cholerae infection
💬
6件:
Adrenergic signaling in cardiomyocytes
,
Cholinergic synapse
,
Gastric acid secretion
,
Pancreatic
...
2件:
2
2
,
144
10
Cannabidiol
1件:
Cannabidiol
Cannabidiol
4件:
CANNABIDIOL
CANNABIDIOL
;
Epidiolex
;
Epidyolex
;
SATIVEX
;
2件:
CNR1
CNR1
,
CNR2
💬
4件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
,
Rap1 signaling pathway
,
Retrograde endocannabinoid signaling
,
Thermogenesis
💬
4件:
Neuroactive ligand-receptor interaction
,
Rap1 signaling pathway
,
Retrograde endocannabinoid sign
...
20件:
2
2
,
6
,
8
,
13
,
36
,
46
,
51
,
95
,
96
,
97
,
140
,
144
,
145
,
156
,
157
,
158
,
193
,
206
,
226
,
271