KEGG DRUG

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KEGG DRUG

DrugBank

薬物名（臨床試験情報から抽出）

KEGG GENES

KEGG PATHWAY

指定難病告示番号

Amiloride 💬

1件: Amiloride (Amiloride Hydrochloride and Hydrochlorothiazide)

3件: Amiloride; Amiloride Hydrochloride; Midamor

3件: SCNN1A,
SCNN1B,
SCNN1G 💬

2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬

4件: 13, 67, 225, 299 💬

告示番号	日本語名	英語名
13	多発性硬化症／視神経脊髄炎	Multiple sclerosis/Neuromyelitis optica
67	多発性嚢胞腎	Polycystic kidney disease
225	先天性腎性尿崩症;遺伝性腎性尿崩症	Congenital nephrogenic diabetes insipidus
299	嚢胞性線維症;膵囊胞線維症	Cystic fibrosis

Amlodipine 💬

1件: Amlodipine (Olmesartan Medoxomil / Amlodipine Besylate / Hydrochlorothiazide)

1件: Amlodipine

4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬

Name	Full Name
CACNA1C	calcium voltage-gated channel subunit alpha1 C
CACNA1D	calcium voltage-gated channel subunit alpha1 D
CACNA1F	calcium voltage-gated channel subunit alpha1 F
CACNA1S	calcium voltage-gated channel subunit alpha1 S

37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, ...

3件: 51, 67, 298 💬

Benazepril 💬

1件: Benazepril (Benazepril Hydrochloride and Hydrochlorothiazide)

1件: Benazepril

1件: ACE 💬

6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyop ...

4件: 49, 57, 218, 224 💬

告示番号	日本語名	英語名
49	全身性エリテマトーデス	Systemic lupus erythematosus
57	特発性拡張型心筋症	Idiopathic dilated cardiomyopathy
218	アルポート症候群	Alport syndrome
224	紫斑病性腎炎	Purpura nephritis

Bisoprolol 💬

1件: Bisoprolol (Bisoprolol Fumarate Hydrochlorothiazide)

2件: BISOPROLOL; Bisoprolol Fumarate

1件: ADRB1 💬

11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - re ...

4件: 58, 67, 86, 113 💬

告示番号	日本語名	英語名
58	肥大型心筋症	Hypertrophic cardiomyopathy
67	多発性嚢胞腎	Polycystic kidney disease
86	肺動脈性肺高血圧症	Pulmonary arterial hypertension
113	筋ジストロフィー	Muscular dystrophy

Candesartan cilexetil

💬

1件: Candesartan cilexetil (Candesartan Cilexetil and Hydrochlorothiazide Tablets)

1件: CANDESARTAN

1件: AGTR1 💬

16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, A ...

1件: 67 💬

Captopril 💬

1件: Captopril (Captopril and Hydrochlorothiazide)

1件: Captopril

1件: ACE 💬

6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyop ...

2件: 17, 86 💬

Enalapril 💬

1件: Enalapril (Enalapril Maleate and Hydrochlorothiazide)

2件: Enalapril; Enalapril Maleate

1件: ACE 💬

6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyop ...

6件: 19, 46, 66, 113, 210, 222 💬

告示番号	日本語名	英語名
19	ライソゾーム病	Lysosomal storage disease
46	悪性関節リウマチ	Malignant rheumatoid arthritis
66	IgA腎症	IgA nephropathy
113	筋ジストロフィー	Muscular dystrophy
210	単心室症	Single Ventricle
222	一次性ネフローゼ症候群	Primary nephrotic syndrome

Hydralazine 💬

1件: Hydralazine (Hydralazine HCl and Hydrochlorothiazide)

1件: Hydralazine

1件: AOC3 💬

5件: Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine ...

1件: 67 💬

Hydrochlorothiazide

💬
(Hydrochlorothiazide (JP18/USP/INN))

1件: Hydrochlorothiazide (Bisoprolol Fumarate Hydrochlorothiazide)

2件: Esidrix; Hydrochlorothiazide

1件: SLC12A3 💬

1件: 💬

4件: 13, 67, 225, 235 💬

告示番号	日本語名	英語名
13	多発性硬化症／視神経脊髄炎	Multiple sclerosis/Neuromyelitis optica
67	多発性嚢胞腎	Polycystic kidney disease
225	先天性腎性尿崩症;遺伝性腎性尿崩症	Congenital nephrogenic diabetes insipidus
235	副甲状腺機能低下症	Hypoparathyroidism

Irbesartan 💬

1件: Irbesartan (Irbesartan Hydrochlorothiazide Zentiva)

2件: Aprovel; IRBESARTAN

1件: AGTR1 💬

16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, A ...

4件: 66, 167, 168, 222 💬

告示番号	日本語名	英語名
66	IgA腎症	IgA nephropathy
167	マルファン症候群	Marfan syndrome
168	エーラス・ダンロス症候群	Ehlers-Danlos syndrome
222	一次性ネフローゼ症候群	Primary nephrotic syndrome

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