Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen 💬1件: Acetaminophen (Otis Clapp Mygrex)4件: Acetaminophen; Paracetamol; Tylenol; Ultracet2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Acetic acid, glacial 💬1件: Acetic acid (Treagan Otic)2件: Acetic acid; Ethanoate--2件: 97, 251 💬
3 Allantoin 💬1件: Allantoin (Burn-B Gone OTC)1件: ALLANTOIN--1件: 36 💬
4 Apremilast 💬
(Otezla (TN))		1件: Apremilast (Otezla)2件: Apremilast; Otezla4件: PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		5件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬7件: 46, 50, 56, 97, 107, 162, 271 💬
5 Baricitinib 💬
(OTHER BARICITINIB)		1件: Baricitinib2件: Baricitinib; Olumiant2件: JAK1,
JAK2 💬 		35件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬13件: 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
6 Betamethasone 💬1件: Betamethasone (Garasone Ophthalmic and Otic Solution)1件: Betamethasone1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬8件: 2, 28, 46, 65, 83, 90, 96, 235 💬
7 Calcium carbonate 💬1件: Calcium carbonate (Relief OTC antacid)3件: Calcio carbonato; Calcium; Calcium Carbonate--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
8 Calcium carbonate 💬1件: Calcium carbonate (Relief OTC antacid)3件: Calcio carbonato; Calcium; Calcium carbonate--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
9 Capsaicin 💬1件: Capsaicin (Pallerix OTC BIOfrequency Chip)2件: Capsaicin; Qutenza1件: TRPV1 💬 2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226 💬
10 Chlorphenamine 💬1件: Chlorpheniramine (Otis Clapp Valihist)1件: Clorfenamina1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14 💬
11 Ciprofloxacin 💬
(Otiprio (TN))		1件: Ciprofloxacin (Cipro HC Otic Suspension)2件: Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE--5件: 2, 60, 96, 97, 299 💬
12 Elasomeran 💬
(OTHER MODERNA COVID-19 VACCINE)		1件: Moderna COVID-19 Vaccine4件: COVID-19 Vaccine Moderna; Elasomeran; Moderna COVID-19 Vaccine; Spikevax--5件: 13, 46, 51, 65, 299 💬
13 Ethanol 💬1件: Ethanol (hand sanitizer OTC)3件: Alcohol; Ethanol; PREDNISONE--5件: 58, 97, 279, 280, 298 💬
14 Fluocinolone acetonide 💬
(FLAC OTIC OIL)		1件: Fluocinolone acetonide (Flac Otic Oil)2件: Fluocinolone Acetonide; Iluvien1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 90 💬
15 Gentamicin 💬1件: Gentamicin (Garasone Ophthalmic and Otic Solution)2件: Gentamicin; Gentamicin Sulfate--3件: 36, 113, 299 💬
16 Ginger 💬1件: Ginger (C Ottways Lax Tab)1件: Ginger--2件: 46, 271 💬
17 Hydrocortisone 💬1件: Hydrocortisone (Oto End 10)6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
18 Hydrocortisone acetate 💬1件: Hydrocortisone acetate (Otizol HC Liq)2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 97 💬
19 Ibuprofen 💬1件: Ibuprofen (Otis Clapp Ultraprin)2件: Ibuprofen; IBUPROFEN 200MG2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299 💬
20 Lidocaine 💬1件: Lidocaine (Otizol HC Liq)4件: Aloe; Lidocaine; Lignocaine; Xylocaine5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
21 Lidocaine hydrochloride monohydrate 💬1件: Lidocaine (Otizol HC Liq)4件: Aloe; Lidocaine; Lignocaine; Xylocaine5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
22 Methotrexate 💬
(Otrexup (TN))		1件: Methotrexate (Otrexup)6件: Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Metoject; Metotrexato; Méthotrexate2件: DHFR,
DHFR2 💬 		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
23 Neomycin 💬1件: Neomycin (Neomycin and Polymyxin B Sulfates and Hydrocortisone Otic Suspension)1件: Neomycin--3件: 96, 97, 296 💬
24 Omeprazole 💬1件: Omeprazole (Prilosec OTC)4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM2件: ATP4A,
ATP4B 💬 		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
25 Otelixizumab 💬
(Otelixizumab (USAN))		1件: Otelixizumab (Otelixizumab)1件: Otelixizumab3件: CD3D,
CD3E,
CD3G 💬 		11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬1件: 46 💬
26 Otilimab 💬
(Otilimab (USAN), Otilimab (genetical recombination) (JAN))		1件: Otilimab (Otilimab)1件: OTILIMAB1件: CSF2 💬 16件: Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬1件: 46 💬
27 Phenylephrine 💬1件: Phenylephrine (Ortizol Otic Solution)1件: Phenylephrine3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22 💬
28 Senna leaf 💬1件: Senna leaf (C Ottways Lax Tab)1件: Senna--1件: 291 💬
29 Sodium bicarbonate 💬1件: Sodium bicarbonate (Relief OTC antacid)1件: Sodium Bicarbonate--1件: 299 💬
30 Tozinameran 💬
(OTHER BNT162B2)		1件: Tozinameran2件: Comirnaty; Tozinameran--5件: 13, 46, 51, 53, 299 💬
31 Zinc acetate 💬1件: Zinc acetate (Otozin)2件: Wilzin; Zinc acetate--2件: 171, 299 💬
32 Zinc oxide 💬1件: Zinc oxide (Coppertone Sunscreen Lotion Defend & Care Clearzinc+ Other Sunscreen Ingredients)1件: Zinc oxide--1件: 156 💬