Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen 💬1件: Acetaminophen (Smart Sense cold flu and sore throat)4件: Acetaminophen; Paracetamol; Tylenol; Ultracet2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Adenosine 💬1件: Adenosine (Smart Recovery)2件: Adenosine; Ginseng4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬 		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65 💬
3 Allantoin 💬1件: Allantoin (Smart Brushing Tooth)1件: ALLANTOIN--1件: 36 💬
4 Aluminum hydroxide 💬1件: Aluminum hydroxide (Smart Sense Antacid)2件: Aluminium hydroxide; Aluminum hydroxide--2件: 11, 46 💬
5 Aspirin 💬1件: Acetylsalicylic acid (Smart Sense Effervescent Antacid and Pain Relief)2件: ACETYLSALICYLIC ACID; Aspirin2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬12件: 13, 22, 46, 49, 51, 58, 64, 86, 113, 158, 210, 231 💬
6 Caffeine 💬1件: Caffeine (Smart Sense migraine relief)1件: Caffeine11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265 💬
7 Caffeine hydrate 💬1件: Caffeine (Smart Sense migraine relief)1件: Caffeine11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265 💬
8 Calcium carbonate 💬1件: Calcium carbonate (Smart Sense Dual Action Complete)3件: Calcio carbonato; Calcium; Calcium carbonate--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
9 Calcium carbonate 💬1件: Calcium carbonate (Smart Sense Dual Action Complete)3件: Calcio carbonato; Calcium; Calcium carbonate--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
10 Capsaicin 💬1件: Capsaicin (SmartRx Gaba-V Kit)2件: Capsaicin; Qutenza1件: TRPV1 💬 2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226 💬
11 Cetirizine 💬1件: Cetirizine (Smart Sense Childrens Allergy)3件: CETIRIZINA; Cetirizine; CETIRIZINE HYDROCHLORIDE1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 28, 35, 300 💬
12 Chlorhexidine 💬1件: Chlorhexidine (Smart San CHG)2件: Chlorhexidine; Chlorhexidine Gluconate--2件: 86, 299 💬
13 Chlorphenamine 💬1件: Chlorpheniramine (Smart Sense Multi Symptom Fever and Cold Childrens)1件: Clorfenamina1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14 💬
14 Cimetidine 💬1件: Cimetidine (Smart Sense Acid Reducer)1件: Cimetidine1件: HRH2 💬 3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 2, 254 💬
15 Citric acid monohydrate 💬1件: Citric acid (Smart Sense Effervescent Antacid and Pain Relief)1件: Citric acid--2件: 53, 291 💬
16 Clotrimazole 💬1件: Clotrimazole (Smart Sense Athletes Foot Antifungal)1件: Clotrimazole--1件: 97 💬
17 Dextromethorphan 💬1件: Dextromethorphan (Smart Sense Adults Tussin CF Multi Symptom Cold)4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
18 Diphenhydramine 💬1件: Diphenhydramine (Smart Sense Itch Stopping)2件: Diphenhydramine; Diphenhydramine hydrochloride1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬8件: 11, 13, 49, 51, 70, 86, 222, 256 💬
19 Esomeprazole 💬1件: Esomeprazole (Smart Sense Esomeprazole Magnesium)3件: Esomeprazole; Nexium; Omeprazole2件: ATP4A,
ATP4B 💬 		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299 💬
20 Ethanol 💬1件: Ethanol (Smart Hand Sanitizer)3件: Alcohol; Ethanol; PREDNISONE--5件: 58, 97, 279, 280, 298 💬
21 Famotidine 💬1件: Famotidine (Smart Sense Acid Reducer Maximum Strength)2件: FAMOTIDINA; Famotidine1件: HRH2 💬 3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬6件: 6, 46, 61, 86, 98, 107 💬
22 Fexofenadine 💬1件: Fexofenadine (Smart Sense Allergy Relief)1件: Fexofenadine1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬2件: 13, 46 💬
23 Fluticasone propionate 💬1件: Fluticasone propionate (Smart Sense Allergy Relief)3件: Flovent; Fluticasone; Fluticasone propionate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬2件: 98, 228 💬
24 Gabapentin 💬1件: Gabapentin (SmartRx Gaba Kit)4件: Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298 💬
25 Glycerin 💬1件: Glycerin (Repiel Smart Foot Mask Ultra Rich)2件: Bee venom; Glycerol--5件: 6, 13, 79, 316, 317 💬
26 Hydrocortisone 💬1件: Hydrocortisone (Smart Sense Anti Itch)6件: Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
27 Hydrocortisone acetate 💬1件: Hydrocortisone acetate (Smart Sense Anti Itch Maximum Strength)2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 97 💬
28 Ibuprofen 💬1件: Ibuprofen (Smart Sense Ibuprofen PM)2件: IBUPROFEN; IBUPROFEN 200MG2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299 💬
29 Lansoprazole 💬1件: Lansoprazole (Smart Sense Acid Reducer)1件: Lansoprazole2件: ATP4A,
ATP4B 💬 		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299 💬
30 Lidocaine 💬1件: Lidocaine (K-Mart SmartSense First Aid Contains 303 Pieces)4件: Aloe; Lidocaine; Lignocaine; Xylocaine5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
31 Lidocaine hydrochloride monohydrate 💬1件: Lidocaine (K-Mart SmartSense First Aid Contains 303 Pieces)4件: Aloe; Lidocaine; Lignocaine; Xylocaine5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
32 Loperamide 💬1件: Loperamide (Smart Sense Loperamide Hydrochloride)2件: Loperamide; Loperamide hydrochloride3件: OPRD1,
OPRK1,
OPRM1 💬 		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 13, 97 💬
33 Loratadine 💬1件: Loratadine (Smart Sense Allergy and Congestion Relief D)2件: Loratadina; LORATADINE1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 46, 89, 98 💬
34 Magnesium hydroxide 💬1件: Magnesium hydroxide (Smart Sense Dual Action Complete)1件: Magnesium hydroxide--1件: 284 💬
35 Magnesium sulfate 💬1件: Magnesium sulfate (Health Smart Natural Epsom Salt)1件: Magnesium sulfate--3件: 11, 296, 297 💬
36 Mineral oil 💬1件: Mineral oil (Smart Sense Hemorrhoidal)1件: Paraffin Oil--1件: 291 💬
37 Minoxidil 💬1件: Minoxidil (Smart Sense Hair Regrowth Treatment)1件: MINOXIDIL2件: ABCC8,
KCNJ11 💬 		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬1件: 179 💬
38 Naproxen 💬1件: Naproxen (Smart Sense naproxen sodium)5件: Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 13, 46, 107, 271 💬
39 Neomycin 💬1件: Neomycin (Smart Sense antibiotic plus pain relief)1件: Neomycin--3件: 96, 97, 296 💬
40 Nicotine 💬1件: Nicotine (Smart Sense Nicotine Polacrilex)2件: NICOTINE; Nicotine gum16件: CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬 		8件: Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬3件: 6, 13, 84 💬
41 Omeprazole 💬1件: Omeprazole (Smart Sense Omeprazole)4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM2件: ATP4A,
ATP4B 💬 		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
42 Petrolatum 💬1件: Petrolatum (Health Smart Cocoa Butter Petroleum)1件: Petrolatum--1件: 158 💬
43 Phenylephrine 💬1件: Phenylephrine (Smart Sense Flu and Severe Cold and Cough Daytime)1件: Phenylephrine3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22 💬
44 Polyethylene glycol 3350 💬1件: Polyethylene glycol (Smart Sense Clearlax)4件: Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350--7件: 6, 78, 96, 97, 235, 276, 299 💬
45 Pseudoephedrine 💬1件: Pseudoephedrine (Smart Sense Allergy Relief D)1件: Pseudoephedrine9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17 💬
46 Ranitidine 💬1件: Ranitidine (Smart Sense Acid Reducer)1件: Ranitidine1件: HRH2 💬 3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 13, 65 💬
47 Salicylic acid 💬1件: Salicylic acid (Clear Smart Clear Pore Hydrator)2件: 2-Hydroxybenzoic acid; Salicylic acid--1件: 97 💬
48 Sodium bicarbonate 💬1件: Sodium bicarbonate (Smart Sense Effervescent Antacid and Pain Relief)1件: Sodium Bicarbonate--1件: 299 💬
49 Sodium fluoride 💬1件: Sodium fluoride (Smart Sense Enamel Guard)1件: Sodium fluoride--1件: 51 💬
50 Thymol 💬1件: Thymol (Smart Sense Citrus)1件: Thymol--1件: 13 💬
51 Triamcinolone 💬1件: Triamcinolone (Smart Sense Nasal Allergy)4件: Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
52 Water 💬1件: Water (K-Mart SmartSense First Aid Contains 303 Pieces)8件: AVONEX; ENBREL; Hiberix; INDOCYANINE GREEN; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION--21件: 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
53 Zinc acetate 💬1件: Zinc acetate (Smart Sense Topical Analgesic Skin Protectant)2件: Wilzin; Zinc acetate--2件: 171, 299 💬
54 Zinc oxide 💬1件: Zinc oxide (Smarth PeriShield)1件: Zinc oxide--1件: 156 💬