Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	TUBB3	10件: Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00570	Colchicine	7件: 2, 42, 46, 56, 93, 210, 266
2	TUBB4A	10件: Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00570	Colchicine	7件: 2, 42, 46, 56, 93, 210, 266
3	TUBB4B	10件: Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00570	Colchicine	7件: 2, 42, 46, 56, 93, 210, 266
4	DHFR	5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ...	D00142	Methotrexate	38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ...
5	DHFR2	5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ...	D00142	Methotrexate	38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ...
6	TUBB	10件: Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00570	Colchicine	7件: 2, 42, 46, 56, 93, 210, 266
7	NR3C1	1件: Neuroactive ligand-receptor interaction	D00385	Triamcinolone	8件: 56, 70, 90, 96, 107, 162, 226, 298
8	NR3C1	1件: Neuroactive ligand-receptor interaction	D00472	Prednisolone	24件: 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, ...
9	HMGCR	4件: Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion	D08492	Rosuvastatin	11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
10	IFNAR1	18件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Necroptosis, Osteoclast dif ...	D00745	Interferon alfa-2a	1件: 56

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