Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 149 1件: 149 💬 |
2 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
SIGMAR1 1件: SIGMAR1 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
3 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 149 1件: 149 💬 |
4 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
HTR2A 2件: HTR2A, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
5 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
6 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
HTR1D 1件: HTR1D 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
7 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 149 1件: 149 💬 |
8 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 149 1件: 149 💬 |
9 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 149 1件: 149 💬 |
10 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
SV2A 1件: SV2A 💬 |
D08879 D08879 💬 |
Brivaracetam | 149 2件: 149, 309 💬 |
11 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
SV2A 3件: SV2A, SV2B, SV2C 💬 |
D11842 D11842 💬 |
Padsevonil | 149 1件: 149 💬 |
12 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
13 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
14 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
HTR2A 2件: HTR2A, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
15 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 149 1件: 149 💬 |
16 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
17 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
HTR2A 2件: HTR2A, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
18 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 14件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬 |
19 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 149 1件: 149 💬 |
20 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
21 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
22 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
HTR1D 3件: HTR1D, HTR2A, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
23 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
SIGMAR1 1件: SIGMAR1 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
24 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
HTR1D 4件: HTR1D, HTR2A, HTR2C, SLC6A4 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
25 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
26 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 14件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬 |
27 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
28 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
HTR1D 1件: HTR1D 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
29 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
SCN3A 2件: SCN3A, SCN9A 💬 |
D07299 D07299 💬 |
Lacosamide | 002 4件: 2 , 46, 149, 298 💬 |
30 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1G 1件: CACNA1G 💬 |
D07971 D07971 💬 |
Flunarizine | 149 1件: 149 💬 |