Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
RARA 1件: RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
2 | Autoimmune thyroid disease 💬 Related to 22 target genes, 15 drugs (DrugBank) and 35 diseases in DDrare |
CTLA4 1件: CTLA4 💬 |
D04603 D04603 💬 |
Ipilimumab | 159 1件: 159 💬 |
3 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CTLA4 1件: CTLA4 💬 |
D04603 D04603 💬 |
Ipilimumab | 159 1件: 159 💬 |
4 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
PDCD1 1件: PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
5 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RARA 1件: RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
6 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RARB 1件: RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
7 | Melanogenesis 💬 Related to 7 target genes, 16 drugs (DrugBank) and 29 diseases in DDrare |
MC1R 1件: MC1R 💬 |
D10511 D10511 💬 |
Afamelanotide | 159 3件: 159, 161, 254 💬 |
8 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
MC1R 1件: MC1R 💬 |
D10511 D10511 💬 |
Afamelanotide | 159 3件: 159, 161, 254 💬 |
9 | Non-small cell lung cancer 💬 Related to 21 target genes, 33 drugs (DrugBank) and 45 diseases in DDrare |
RARB 1件: RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
10 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
RARA 2件: RARA, RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
11 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
PDCD1 1件: PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
12 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
CTLA4 1件: CTLA4 💬 |
D04603 D04603 💬 |
Ipilimumab | 159 1件: 159 💬 |
13 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
RARB 1件: RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
14 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
CTLA4 1件: CTLA4 💬 |
D04603 D04603 💬 |
Ipilimumab | 159 1件: 159 💬 |
15 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
PDCD1 1件: PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
16 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
RARA 1件: RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
17 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RARA 1件: RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |