Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
2 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
3 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
4 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
5 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
DRD1 2件: DRD1, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
6 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD1 3件: DRD1, DRD2, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
7 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
8 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
9 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
10 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD1 5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
11 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
12 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
13 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
14 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
15 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
16 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
DRD1 5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
17 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
18 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
19 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
20 | Phenylalanine metabolism 💬 Related to 6 target genes, 12 drugs (DrugBank) and 15 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
21 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
22 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
23 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
24 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
25 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
26 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 12 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
27 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 18 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |