Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
2 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
3 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
4 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
5 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
6 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
7 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
8 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 |
9 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
10 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
11 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
12 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
13 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
14 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
15 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
16 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 |
17 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
18 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
19 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
GRIA1 7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
20 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
21 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
22 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
23 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 43 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
24 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
25 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
26 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
27 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
GRIN1 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
28 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
GRIN1 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
29 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
GRIN1 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
30 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
31 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
32 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
OXTR 1件: OXTR 💬 |
D00089 D00089 💬 |
Oxytocin | 006 7件: 6 , 72, 127, 168, 193, 206, 226 💬 |
33 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
34 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD2 2件: DRD2, HTR1A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
35 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 2件: 13, 206 💬 |
36 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
37 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
38 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
39 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
40 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
OXTR 1件: OXTR 💬 |
D00089 D00089 💬 |
Oxytocin | 006 7件: 6 , 72, 127, 168, 193, 206, 226 💬 |
41 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
42 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
PDE4D 1件: PDE4D 💬 |
D12173 D12173 💬 |
Zatolmilast | 206 1件: 206 💬 |
43 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 40 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
44 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
ACHE 1件: ACHE 💬 |
D07869 D07869 💬 |
Donepezil | 005 9件: 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 |
45 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
46 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
47 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
48 | Circadian rhythm 💬 Related to 2 target genes, 1 drug (DrugBank) and 25 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
49 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
50 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
51 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
GRIA2 6件: GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
52 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
53 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
54 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 |
55 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
56 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD2 2件: DRD2, DRD3 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
57 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
GRIA1 6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
58 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
59 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
60 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 |
61 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 2件: 13, 206 💬 |
62 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
63 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
64 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
65 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 2件: 13, 206 💬 |
66 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
67 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
68 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
69 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 4件: 145, 152, 158, 206 💬 |
70 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 2件: DRD2, HTR2A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
71 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 2件: DRD2, HTR2A 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
72 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
73 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIA1 14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
74 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
75 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
76 | Glycerophospholipid metabolism 💬 Related to 1 target gene, 5 drugs (DrugBank) and 11 diseases in DDrare |
ACHE 1件: ACHE 💬 |
D07869 D07869 💬 |
Donepezil | 005 9件: 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 |
77 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 2件: 13, 206 💬 |
78 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
79 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
80 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
81 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
GRIA1 6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
82 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
GRIN1 2件: GRIN1, GRIN2B 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
83 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
GRIN1 2件: GRIN1, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
84 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
85 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
86 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
87 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
88 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
89 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
90 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
91 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
92 | Long-term depression 💬 Related to 13 target genes, 19 drugs (DrugBank) and 32 diseases in DDrare |
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
93 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
GRIA1 7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
94 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
95 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
96 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
97 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
98 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
99 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
100 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE4D 1件: PDE4D 💬 |
D12173 D12173 💬 |
Zatolmilast | 206 1件: 206 💬 |
101 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
102 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
103 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 2件: 13, 206 💬 |
104 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
105 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
106 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
107 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 4件: 145, 152, 158, 206 💬 |
108 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
109 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
PDE4D 1件: PDE4D 💬 |
D12173 D12173 💬 |
Zatolmilast | 206 1件: 206 💬 |
110 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
111 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
CNR1 2件: CNR1, CNR2 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 20件: 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
112 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
DRD2 4件: DRD2, DRD3, HTR1A, HTR2A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
113 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
DRD2 2件: DRD2, HTR2A 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
114 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 2件: 13, 206 💬 |
115 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
116 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
117 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
118 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 4件: 145, 152, 158, 206 💬 |
119 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GRIA1 14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
120 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
121 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
122 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
OXTR 1件: OXTR 💬 |
D00089 D00089 💬 |
Oxytocin | 006 7件: 6 , 72, 127, 168, 193, 206, 226 💬 |
123 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
124 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
125 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
126 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 4件: 145, 152, 158, 206 💬 |
127 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
128 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
129 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
130 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
131 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
132 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
OXTR 1件: OXTR 💬 |
D00089 D00089 💬 |
Oxytocin | 006 7件: 6 , 72, 127, 168, 193, 206, 226 💬 |
133 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
134 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
135 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
136 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PDE4D 1件: PDE4D 💬 |
D12173 D12173 💬 |
Zatolmilast | 206 1件: 206 💬 |
137 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
138 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
139 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 |
140 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
141 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
142 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
143 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
144 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
145 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 |
146 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
147 | Platelet activation 💬 Related to 22 target genes, 51 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 1件: PTGS1 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
148 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
149 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
150 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
151 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
152 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE4D 1件: PDE4D 💬 |
D12173 D12173 💬 |
Zatolmilast | 206 1件: 206 💬 |
153 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
CNR1 1件: CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 20件: 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
154 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
155 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
156 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
157 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
158 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
159 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
160 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
161 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
162 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
163 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CNR1 1件: CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 20件: 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
164 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
165 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
166 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 4件: 145, 152, 158, 206 💬 |
167 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GRIA1 4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
168 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
169 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
170 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
171 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 4件: 145, 152, 158, 206 💬 |
172 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
HTR1A 2件: HTR1A, HTR2A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
173 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
174 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
175 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D00326 D00326 💬 |
Fluoxetine | 013 6件: 13, 17, 78, 86, 179, 206 💬 |
176 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D02360 D02360 💬 |
Sertraline | 006 2件: 6 , 206 💬 |
177 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
178 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIA1 8件: GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
179 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
180 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
181 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 2件: SLC6A2, SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 |
182 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D00326 D00326 💬 |
Fluoxetine | 013 6件: 13, 17, 78, 86, 179, 206 💬 |
183 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D02360 D02360 💬 |
Sertraline | 006 2件: 6 , 206 💬 |
184 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
185 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
186 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
187 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 2件: 13, 206 💬 |
188 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
189 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
190 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 2件: 201, 206 💬 |
191 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 4件: 145, 152, 158, 206 💬 |
192 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
HTR1A 1件: HTR1A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
193 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
194 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
CNR1 1件: CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 20件: 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
195 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
196 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
197 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
198 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
GRIA3 1件: GRIA3 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
199 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |