Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 2 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 3 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
PDE2A 1件: PDE2A 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 4 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
PDE2A 1件: PDE2A 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 5 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 6 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 7 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADORA2B 4件: ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 8 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADORA2B 4件: ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 9 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADORA1 8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 10 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADORA1 8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 11 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADORA1 4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 12 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADORA1 4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 13 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 14 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 15 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
PDE11A 3件: PDE11A, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 16 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
PDE11A 3件: PDE11A, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 17 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 18 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 19 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 20 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 21 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 22 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 23 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 24 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 25 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 26 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 27 | Olfactory transduction 💬 Related to 4 target genes, 5 drugs (DrugBank) and 13 diseases in DDrare |
PDE1A 4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 28 | Olfactory transduction 💬 Related to 4 target genes, 5 drugs (DrugBank) and 13 diseases in DDrare |
PDE1A 4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 29 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 30 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 31 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 32 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 33 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 34 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 35 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 36 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 37 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 2件: ADORA1, PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 38 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 2件: ADORA1, PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 39 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 40 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 41 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 42 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 43 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
PDE1A 3件: PDE1A, PDE1B, PDE1C 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 44 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
PDE1A 3件: PDE1A, PDE1B, PDE1C 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 45 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 46 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |