Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
2 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 1件: 76 💬 |
3 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
4 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
AR 1件: AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 |
5 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
6 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
PGR 1件: PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 1件: 76 💬 |
7 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
8 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
9 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
10 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
11 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR 1件: PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 1件: 76 💬 |
12 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
13 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
14 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
GNRHR 1件: GNRHR 💬 |
D08027 D08027 💬 |
Gonadorelin | 076 1件: 76 💬 |
15 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
GNRHR 1件: GNRHR 💬 |
D02369 D02369 💬 |
Histrelin | 076 1件: 76 💬 |
16 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
GNRHR 1件: GNRHR 💬 |
D06247 D06247 💬 |
Triptorelin | 049 2件: 49, 76 💬 |
17 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GNRHR 1件: GNRHR 💬 |
D08027 D08027 💬 |
Gonadorelin | 076 1件: 76 💬 |
18 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GNRHR 1件: GNRHR 💬 |
D02369 D02369 💬 |
Histrelin | 076 1件: 76 💬 |
19 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GNRHR 1件: GNRHR 💬 |
D06247 D06247 💬 |
Triptorelin | 049 2件: 49, 76 💬 |
20 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
AR 1件: AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 |
21 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PGR 1件: PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 1件: 76 💬 |
22 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
23 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
AR 1件: AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 |
24 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
25 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PGR 1件: PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 1件: 76 💬 |
26 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
27 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
28 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
AR 1件: AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 |
29 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
30 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |