Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
2 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
3 | Adherens junction 💬 Related to 9 target genes, 19 drugs (DrugBank) and 23 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
4 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
5 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
6 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
7 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
8 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
9 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
10 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
11 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
12 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
13 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
14 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
15 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
16 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
17 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
18 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
19 | Alanine, aspartate and glutamate metabolism 💬 Related to 5 target genes, 3 drugs (DrugBank) and 19 diseases in DDrare |
ABAT 4件: ABAT, ALDH5A1, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
20 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
21 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
22 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
23 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
24 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
ADORA2A 2件: ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
25 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
26 | Aldosterone-regulated sodium reabsorption 💬 Related to 13 target genes, 14 drugs (DrugBank) and 25 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
27 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
28 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
29 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
30 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
31 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
32 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
33 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
34 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
35 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
36 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
37 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
38 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
39 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
40 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
41 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
42 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |
43 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
44 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
45 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
46 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
47 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
48 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
49 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
50 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
51 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
52 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
53 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
54 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
55 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
56 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
57 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
58 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
59 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
60 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
61 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
62 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
63 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
64 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
65 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |
66 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
67 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
68 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
69 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
70 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
71 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
72 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
73 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
74 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
75 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
76 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
77 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
78 | Apoptosis - multiple species 💬 Related to 3 target genes, 3 drugs (DrugBank) and 9 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
79 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 43 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
80 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 8 diseases in DDrare |
ODC1 1件: ODC1 💬 |
D07883 D07883 💬 |
Eflornithine | 065 1件: 65 💬 |
81 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
FCER1A 1件: FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 7件: 46, 53, 65, 98, 162, 226, 299 💬 |
82 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
83 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
84 | Autoimmune thyroid disease 💬 Related to 22 target genes, 15 drugs (DrugBank) and 35 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
85 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
86 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
87 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
88 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
89 | Autophagy - other 💬 Related to 1 target gene, 3 drugs (DrugBank) and 41 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
90 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
91 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
92 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
93 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
94 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
95 | B cell receptor signaling pathway 💬 Related to 19 target genes, 29 drugs (DrugBank) and 68 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
96 | B cell receptor signaling pathway 💬 Related to 19 target genes, 29 drugs (DrugBank) and 68 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
97 | B cell receptor signaling pathway 💬 Related to 19 target genes, 29 drugs (DrugBank) and 68 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
98 | B cell receptor signaling pathway 💬 Related to 19 target genes, 29 drugs (DrugBank) and 68 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
99 | Bacterial invasion of epithelial cells 💬 Related to 5 target genes, 7 drugs (DrugBank) and 13 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
100 | beta-Alanine metabolism 💬 Related to 4 target genes, 3 drugs (DrugBank) and 17 diseases in DDrare |
ABAT 3件: ABAT, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
101 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
102 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
VKORC1 1件: VKORC1 💬 |
D08354 D08354 💬 |
Phenindione | 065 1件: 65 💬 |
103 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
104 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
105 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
106 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
107 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
108 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
109 | Butanoate metabolism 💬 Related to 4 target genes, 2 drugs (DrugBank) and 16 diseases in DDrare |
ABAT 4件: ABAT, ALDH5A1, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
110 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
111 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
112 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
113 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
114 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
115 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
116 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
117 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
118 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADORA2A 2件: ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
119 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
120 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
121 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
122 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
HRH2 1件: HRH2 💬 |
D00422 D00422 💬 |
Ranitidine | 013 2件: 13, 65 💬 |
123 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
124 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
125 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
126 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA2A 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
127 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
128 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
129 | Carbohydrate digestion and absorption 💬 Related to 14 target genes, 19 drugs (DrugBank) and 30 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
130 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD58 1件: CD58 💬 |
D02800 D02800 💬 |
Alefacept | 037 6件: 37, 60, 65, 164, 284, 285 💬 |
131 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
132 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
133 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
134 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
135 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
136 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
137 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
138 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
139 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
140 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA3 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
141 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬 |
D00281 D00281 💬 |
Clonidine | 006 4件: 6 , 65, 70, 78 💬 |
142 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
143 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
144 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
145 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
146 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
147 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
148 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
149 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
150 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
151 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 40 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
152 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
153 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
AR 3件: AR, ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
154 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
155 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
156 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
157 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
158 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
159 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
160 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
161 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
162 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
163 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
JAK2 2件: JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
164 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
165 | Choline metabolism in cancer 💬 Related to 11 target genes, 25 drugs (DrugBank) and 53 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
166 | Choline metabolism in cancer 💬 Related to 11 target genes, 25 drugs (DrugBank) and 53 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
167 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
168 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
169 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
170 | Chronic myeloid leukemia 💬 Related to 17 target genes, 20 drugs (DrugBank) and 29 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
171 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
172 | Circadian rhythm 💬 Related to 2 target genes, 1 drug (DrugBank) and 25 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
173 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05353 D05353 💬 |
Pantoprazole | 013 2件: 13, 65 💬 |
174 | Colorectal cancer 💬 Related to 14 target genes, 23 drugs (DrugBank) and 49 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
175 | Colorectal cancer 💬 Related to 14 target genes, 23 drugs (DrugBank) and 49 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
176 | Colorectal cancer 💬 Related to 14 target genes, 23 drugs (DrugBank) and 49 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
177 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
178 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
179 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
180 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
181 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
182 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
183 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
184 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
185 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
186 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
187 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
188 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
189 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
190 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
191 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
192 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
193 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
194 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
195 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
MPL 1件: MPL 💬 |
D08990 D08990 💬 |
Romiplostim | 060 4件: 60, 63, 64, 65 💬 |
196 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
197 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
198 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
199 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
200 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
201 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
202 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
203 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
204 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
205 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 48 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D00161 D00161 💬 |
Mercaptopurine | 065 4件: 65, 96, 97, 164 💬 |
206 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 48 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D04931 D04931 💬 |
Mercaptopurine | 065 4件: 65, 96, 97, 164 💬 |
207 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 48 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
208 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 48 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
209 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 48 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 011 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
210 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 48 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
211 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
212 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
213 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
214 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
215 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
216 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
217 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
218 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
219 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
220 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
PTH1R 1件: PTH1R 💬 |
D05364 D05364 💬 |
Parathyroid hormone | 065 4件: 65, 70, 235, 326 💬 |
221 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
PTH1R 1件: PTH1R 💬 |
D06078 D06078 💬 |
Teriparatide | 046 7件: 46, 65, 68, 70, 71, 235, 274 💬 |
222 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
223 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
224 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
225 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
226 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
227 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
228 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
229 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
230 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
231 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
232 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
233 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
234 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
235 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
236 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
237 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CD58 1件: CD58 💬 |
D02800 D02800 💬 |
Alefacept | 037 6件: 37, 60, 65, 164, 284, 285 💬 |
238 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
239 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
240 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
241 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
242 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
243 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
244 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
245 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
246 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
247 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 2件: ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
248 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
249 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
250 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
FCER1A 1件: FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 7件: 46, 53, 65, 98, 162, 226, 299 💬 |
251 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
252 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
253 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
254 | Fc gamma R-mediated phagocytosis 💬 Related to 9 target genes, 12 drugs (DrugBank) and 15 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
255 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
256 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
257 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
258 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
259 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
260 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
261 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
262 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
263 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
264 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
265 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
266 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
267 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ABAT 3件: ABAT, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
268 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
269 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
270 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |
271 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05353 D05353 💬 |
Pantoprazole | 013 2件: 13, 65 💬 |
272 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
HRH2 1件: HRH2 💬 |
D00422 D00422 💬 |
Ranitidine | 013 2件: 13, 65 💬 |
273 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
274 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
275 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
276 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
277 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
278 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
279 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
280 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
281 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
282 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
283 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
284 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
285 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
286 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
ODC1 1件: ODC1 💬 |
D07883 D07883 💬 |
Eflornithine | 065 1件: 65 💬 |
287 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 011 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
288 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
289 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
290 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
291 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
292 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
293 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
294 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
295 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
296 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
297 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
298 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
299 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
300 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
301 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
302 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
303 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
304 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
305 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
306 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
307 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
308 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
MS4A1 1件: MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 011 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
309 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
310 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
311 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
312 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
313 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
314 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
315 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
316 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
317 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
318 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
319 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
320 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
321 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
322 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
323 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
324 | Hepatocellular carcinoma 💬 Related to 21 target genes, 31 drugs (DrugBank) and 57 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
325 | Hepatocellular carcinoma 💬 Related to 21 target genes, 31 drugs (DrugBank) and 57 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
326 | Hepatocellular carcinoma 💬 Related to 21 target genes, 31 drugs (DrugBank) and 57 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
327 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
328 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
329 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
330 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
331 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
332 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
333 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
334 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
335 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
336 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
337 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
338 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
339 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
340 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
341 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
342 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
343 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
344 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
345 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
346 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
347 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
348 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
349 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
350 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
351 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
352 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
353 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
354 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
355 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
356 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
357 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
358 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
359 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
360 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
361 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
362 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
363 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
364 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
365 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
366 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
367 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
368 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
369 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
370 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
371 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
372 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
373 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
374 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
375 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
376 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
377 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
JAK1 2件: JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
378 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
379 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
380 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
381 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
382 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
383 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
384 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
385 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
386 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
387 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
388 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |
389 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
390 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
391 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
392 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
393 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
394 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
395 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
396 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
397 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
398 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
399 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IL2RG 1件: IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
400 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
401 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
402 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
403 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
404 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
405 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
406 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
407 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
408 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
409 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
410 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
411 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
412 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
413 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
414 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
415 | Inositol phosphate metabolism 💬 Related to 3 target genes, 3 drugs (DrugBank) and 5 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
416 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
417 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
418 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
419 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
420 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
421 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
422 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
423 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
424 | Intestinal immune network for IgA production 💬 Related to 16 target genes, 27 drugs (DrugBank) and 47 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
425 | Intestinal immune network for IgA production 💬 Related to 16 target genes, 27 drugs (DrugBank) and 47 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
426 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
427 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
428 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
429 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
430 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
431 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
432 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
433 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
434 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
435 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
436 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
MPL 1件: MPL 💬 |
D08990 D08990 💬 |
Romiplostim | 060 4件: 60, 63, 64, 65 💬 |
437 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
438 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
439 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
440 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
441 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
IFNGR1 1件: IFNGR1 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
442 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
443 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
444 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
445 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
446 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
447 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
448 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
449 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
450 | Legionellosis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 61 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
451 | Legionellosis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 61 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
452 | Legionellosis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
453 | Legionellosis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
454 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
455 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
456 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
457 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
458 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
459 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
460 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
461 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
462 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
463 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
464 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
465 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
466 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
467 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
468 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
469 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
470 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
471 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
472 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
473 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
474 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
475 | Long-term depression 💬 Related to 13 target genes, 19 drugs (DrugBank) and 32 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
476 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
477 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
478 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
479 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
480 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
481 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
482 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
483 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
484 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
485 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
486 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
487 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
488 | Malaria 💬 Related to 15 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
489 | Malaria 💬 Related to 15 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
IL12A 1件: IL12A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
490 | Malaria 💬 Related to 15 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
491 | Malaria 💬 Related to 15 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
492 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
493 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
494 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
495 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
496 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
497 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
498 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
499 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
500 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
501 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
502 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
503 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
504 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
505 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
506 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
507 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
508 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
509 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
510 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ABAT 4件: ABAT, ALDH5A1, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
511 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05353 D05353 💬 |
Pantoprazole | 013 2件: 13, 65 💬 |
512 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
513 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
514 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
515 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D00161 D00161 💬 |
Mercaptopurine | 065 4件: 65, 96, 97, 164 💬 |
516 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D04931 D04931 💬 |
Mercaptopurine | 065 4件: 65, 96, 97, 164 💬 |
517 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
518 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
519 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ODC1 1件: ODC1 💬 |
D07883 D07883 💬 |
Eflornithine | 065 1件: 65 💬 |
520 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
521 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
522 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 011 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
523 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
524 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
VKORC1 1件: VKORC1 💬 |
D08354 D08354 💬 |
Phenindione | 065 1件: 65 💬 |
525 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
526 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
527 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
528 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
529 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
530 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
531 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
532 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
533 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
534 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
535 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
536 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
537 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
538 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
539 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
540 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
541 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
542 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
543 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
544 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
545 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
546 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
547 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
548 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
549 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
550 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
551 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADORA1 4件: ADORA1, ADORA2A, ADORA2B, ADORA3 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
552 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬 |
D00281 D00281 💬 |
Clonidine | 006 4件: 6 , 65, 70, 78 💬 |
553 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
554 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
555 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
HRH2 1件: HRH2 💬 |
D00422 D00422 💬 |
Ranitidine | 013 2件: 13, 65 💬 |
556 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00244 D00244 💬 |
Betamethasone | 002 8件: 2 , 28, 46, 65, 83, 90, 96, 235 💬 |
557 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00292 D00292 💬 |
Dexamethasone | 013 22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
558 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 46件: 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
559 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00472 D00472 💬 |
Prednisolone | 003 42件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
560 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 45件: 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 |
561 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
PTH1R 1件: PTH1R 💬 |
D06078 D06078 💬 |
Teriparatide | 046 7件: 46, 65, 68, 70, 71, 235, 274 💬 |
562 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
PTH1R 2件: PTH1R, PTH2R 💬 |
D05364 D05364 💬 |
Parathyroid hormone | 065 4件: 65, 70, 235, 326 💬 |
563 | Neurotrophin signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 32 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
564 | Neutrophil extracellular trap formation 💬 Related to 35 target genes, 36 drugs (DrugBank) and 61 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
565 | Neutrophil extracellular trap formation 💬 Related to 35 target genes, 36 drugs (DrugBank) and 61 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
566 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
567 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
568 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
569 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
570 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
571 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
572 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
573 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
574 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
575 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
576 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
577 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
578 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
579 | Non-small cell lung cancer 💬 Related to 21 target genes, 33 drugs (DrugBank) and 45 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
580 | Non-small cell lung cancer 💬 Related to 21 target genes, 33 drugs (DrugBank) and 45 diseases in DDrare |
JAK3 1件: JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
581 | Non-small cell lung cancer 💬 Related to 21 target genes, 33 drugs (DrugBank) and 45 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
582 | Nucleotide metabolism 💬 Related to 7 target genes, 12 drugs (DrugBank) and 46 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D00161 D00161 💬 |
Mercaptopurine | 065 4件: 65, 96, 97, 164 💬 |
583 | Nucleotide metabolism 💬 Related to 7 target genes, 12 drugs (DrugBank) and 46 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D04931 D04931 💬 |
Mercaptopurine | 065 4件: 65, 96, 97, 164 💬 |
584 | Nucleotide metabolism 💬 Related to 7 target genes, 12 drugs (DrugBank) and 46 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
585 | Nucleotide metabolism 💬 Related to 7 target genes, 12 drugs (DrugBank) and 46 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
586 | Nucleotide metabolism 💬 Related to 7 target genes, 12 drugs (DrugBank) and 46 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 011 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
587 | Nucleotide metabolism 💬 Related to 7 target genes, 12 drugs (DrugBank) and 46 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
588 | One carbon pool by folate 💬 Related to 3 target genes, 2 drugs (DrugBank) and 38 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
589 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
AR 2件: AR, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
590 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
591 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
592 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
593 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
594 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
595 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
596 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
597 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
598 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
599 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
600 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
601 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
602 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
603 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
604 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
605 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
606 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
607 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
608 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05353 D05353 💬 |
Pantoprazole | 013 2件: 13, 65 💬 |
609 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
610 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
611 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
612 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
613 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
614 | p53 signaling pathway 💬 Related to 5 target genes, 4 drugs (DrugBank) and 13 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
615 | p53 signaling pathway 💬 Related to 5 target genes, 4 drugs (DrugBank) and 13 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
616 | Pancreatic cancer 💬 Related to 19 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
617 | Pancreatic cancer 💬 Related to 19 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
618 | Pancreatic cancer 💬 Related to 19 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
619 | Pancreatic cancer 💬 Related to 19 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
620 | Pancreatic cancer 💬 Related to 19 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
621 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PTH1R 1件: PTH1R 💬 |
D05364 D05364 💬 |
Parathyroid hormone | 065 4件: 65, 70, 235, 326 💬 |
622 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PTH1R 1件: PTH1R 💬 |
D06078 D06078 💬 |
Teriparatide | 046 7件: 46, 65, 68, 70, 71, 235, 274 💬 |
623 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
624 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
625 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
626 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
627 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |
628 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
629 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
630 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
631 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
632 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
633 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |
634 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
AR 2件: AR, ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
635 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
636 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
637 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
638 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
639 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
640 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
641 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
642 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
643 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
644 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
645 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
646 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
647 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
648 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
649 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
650 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
651 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
652 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
653 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
654 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
655 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
656 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
657 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
658 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
659 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
660 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
661 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
662 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
663 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |
664 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
665 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
666 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
667 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
668 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
669 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
670 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
671 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
672 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
673 | Pertussis 💬 Related to 18 target genes, 38 drugs (DrugBank) and 66 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
674 | Pertussis 💬 Related to 18 target genes, 38 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
675 | Pertussis 💬 Related to 18 target genes, 38 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
676 | Phagosome 💬 Related to 13 target genes, 10 drugs (DrugBank) and 21 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
677 | Phagosome 💬 Related to 13 target genes, 10 drugs (DrugBank) and 21 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |
678 | Phosphatidylinositol signaling system 💬 Related to 4 target genes, 4 drugs (DrugBank) and 6 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
679 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
FCER1A 1件: FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 7件: 46, 53, 65, 98, 162, 226, 299 💬 |
680 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
681 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
682 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
683 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
684 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
685 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
686 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
GHR 2件: GHR, IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
687 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
688 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
689 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
690 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
691 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
692 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
693 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
694 | Platelet activation 💬 Related to 22 target genes, 51 drugs (DrugBank) and 56 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
695 | Platelet activation 💬 Related to 22 target genes, 51 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 1件: PTGS1 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
696 | Platinum drug resistance 💬 Related to 9 target genes, 15 drugs (DrugBank) and 23 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
697 | Platinum drug resistance 💬 Related to 9 target genes, 15 drugs (DrugBank) and 23 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
698 | Platinum drug resistance 💬 Related to 9 target genes, 15 drugs (DrugBank) and 23 diseases in DDrare |
TOP2A 2件: TOP2A, TOP2B 💬 |
D07776 D07776 💬 |
Daunorubicin | 065 1件: 65 💬 |
699 | Platinum drug resistance 💬 Related to 9 target genes, 15 drugs (DrugBank) and 23 diseases in DDrare |
TOP2A 2件: TOP2A, TOP2B 💬 |
D03899 D03899 💬 |
Doxorubicin | 026 5件: 26, 28, 34, 65, 331 💬 |
700 | Platinum drug resistance 💬 Related to 9 target genes, 15 drugs (DrugBank) and 23 diseases in DDrare |
TOP2A 2件: TOP2A, TOP2B 💬 |
D00125 D00125 💬 |
Etoposide | 011 11件: 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬 |
701 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
702 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D10893 D10893 💬 |
Acalabrutinib | 046 2件: 46, 61 💬 |
703 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D11478 D11478 💬 |
Branebrutinib | 046 3件: 46, 49, 53 💬 |
704 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D12467 D12467 💬 |
Evobrutinib | 013 3件: 13, 46, 49 💬 |
705 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D11457 D11457 💬 |
Fenebrutinib | 013 1件: 13 💬 |
706 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D10223 D10223 💬 |
Ibrutinib | 028 3件: 28, 60, 61 💬 |
707 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 |
708 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D12285 D12285 💬 |
Remibrutinib | 013 2件: 13, 53 💬 |
709 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 |
710 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD19 1件: CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 4件: 11, 13, 51, 300 💬 |
711 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD19 1件: CD19 💬 |
D11496 D11496 💬 |
Obexelimab | 300 1件: 300 💬 |
712 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD3D 2件: CD3D, CD3E 💬 |
D08959 D08959 💬 |
Otelixizumab | 046 1件: 46 💬 |
713 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD3D 2件: CD3D, CD3E 💬 |
D06314 D06314 💬 |
Visilizumab | 096 2件: 96, 97 💬 |
714 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD3E 1件: CD3E 💬 |
D11463 D11463 💬 |
Mosunetuzumab | 049 1件: 49 💬 |
715 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD4 1件: CD4 💬 |
D06356 D06356 💬 |
Zanolimumab | 046 1件: 46 💬 |
716 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40 1件: CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 1件: 222 💬 |
717 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40 1件: CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 2件: 49, 53 💬 |
718 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40 1件: CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 2件: 53, 97 💬 |
719 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
720 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
IL2RG 1件: IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
721 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
JAK3 1件: JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 1件: 46 💬 |
722 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
JAK3 1件: JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
723 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
LCK 1件: LCK 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
724 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
LCK 1件: LCK 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
725 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
TNFRSF13C 1件: TNFRSF13C 💬 |
D12151 D12151 💬 |
Ianalumab | 035 7件: 35, 46, 49, 53, 61, 63, 95 💬 |
726 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
727 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
728 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
729 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
730 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
731 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
732 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
733 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
734 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |
735 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
736 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PGR 1件: PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
737 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
738 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
739 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
740 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
741 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
742 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
743 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
744 | Propanoate metabolism 💬 Related to 1 target gene, 2 drugs (DrugBank) and 16 diseases in DDrare |
ABAT 1件: ABAT 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
745 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
AR 1件: AR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
746 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
747 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
748 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
749 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
750 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
751 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
752 | Proteasome 💬 Related to 2 target genes, 5 drugs (DrugBank) and 20 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
753 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
754 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
755 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
756 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
757 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
IL12B 1件: IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
758 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
759 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
760 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
761 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
762 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D00161 D00161 💬 |
Mercaptopurine | 065 4件: 65, 96, 97, 164 💬 |
763 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D04931 D04931 💬 |
Mercaptopurine | 065 4件: 65, 96, 97, 164 💬 |
764 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
765 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
766 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 011 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
767 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
768 | Pyrimidine metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 36 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 011 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
769 | Pyrimidine metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 36 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
770 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A 2件: ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
771 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
772 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
773 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
774 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
775 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
776 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
777 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
778 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
779 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
780 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
781 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
782 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
783 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
784 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
785 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
786 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
787 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
788 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
789 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
790 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
791 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
792 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
793 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
794 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
795 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
796 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
797 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
798 | Salmonella infection 💬 Related to 27 target genes, 40 drugs (DrugBank) and 66 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
799 | Salmonella infection 💬 Related to 27 target genes, 40 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
800 | Salmonella infection 💬 Related to 27 target genes, 40 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
801 | Salmonella infection 💬 Related to 27 target genes, 40 drugs (DrugBank) and 66 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
802 | Salmonella infection 💬 Related to 27 target genes, 40 drugs (DrugBank) and 66 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |
803 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
804 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
805 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
806 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
807 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
808 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
809 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 19 target genes, 28 drugs (DrugBank) and 48 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
810 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 19 target genes, 28 drugs (DrugBank) and 48 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
811 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 19 target genes, 28 drugs (DrugBank) and 48 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
812 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 19 target genes, 28 drugs (DrugBank) and 48 diseases in DDrare |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
813 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 19 target genes, 28 drugs (DrugBank) and 48 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
814 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
815 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
816 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
817 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA3 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
818 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
FCER1A 1件: FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 7件: 46, 53, 65, 98, 162, 226, 299 💬 |
819 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
820 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
821 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
822 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
823 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
824 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
825 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
826 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
827 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
828 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
829 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
830 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
831 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
832 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
833 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
834 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
835 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
836 | Taurine and hypotaurine metabolism 💬 Related to 2 target genes, 1 drug (DrugBank) and 14 diseases in DDrare |
GAD1 2件: GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
837 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
838 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
839 | TGF-beta signaling pathway 💬 Related to 10 target genes, 20 drugs (DrugBank) and 55 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
840 | TGF-beta signaling pathway 💬 Related to 10 target genes, 20 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
841 | TGF-beta signaling pathway 💬 Related to 10 target genes, 20 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
842 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
843 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
844 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
845 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
846 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
847 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
848 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
849 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
850 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
851 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
852 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
853 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
854 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
855 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
856 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
857 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
858 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
859 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
860 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
861 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
862 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
863 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
864 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
865 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
866 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
867 | Thyroid cancer 💬 Related to 8 target genes, 16 drugs (DrugBank) and 28 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
868 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
869 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
870 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
871 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
872 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
873 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
874 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
875 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
876 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
877 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
878 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
879 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
880 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
881 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
882 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
883 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
884 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
885 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
886 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
887 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
888 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
889 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
890 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
891 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
892 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
893 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
894 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
895 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL2RB 1件: IL2RB 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
896 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
897 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
898 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
899 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
900 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
901 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
902 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
903 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
904 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
905 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
906 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
907 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
908 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
909 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
910 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
GAD1 2件: GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
911 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
912 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
913 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
914 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
915 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1G 1件: CACNA1G 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
916 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
917 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
918 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
919 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
920 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 Related to 3 target genes, 3 drugs (DrugBank) and 14 diseases in DDrare |
VKORC1 1件: VKORC1 💬 |
D08354 D08354 💬 |
Phenindione | 065 1件: 65 💬 |
921 | Valine, leucine and isoleucine degradation 💬 Related to 1 target gene, 2 drugs (DrugBank) and 16 diseases in DDrare |
ABAT 1件: ABAT 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
922 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A 2件: ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
923 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
924 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
925 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
926 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
927 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
928 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
929 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
930 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 2件: JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
931 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
932 | Viral life cycle - HIV-1 💬 Related to 4 target genes, 5 drugs (DrugBank) and 9 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
933 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
934 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
935 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
936 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
937 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
938 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
939 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
940 | Virion - Adenovirus 💬 Related to 2 target genes, 2 drugs (DrugBank) and 26 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
941 | Virion - Human immunodeficiency virus 💬 Related to 3 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
942 | Wnt signaling pathway 💬 Related to 9 target genes, 9 drugs (DrugBank) and 61 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
943 | Wnt signaling pathway 💬 Related to 9 target genes, 9 drugs (DrugBank) and 61 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
944 | Wnt signaling pathway 💬 Related to 9 target genes, 9 drugs (DrugBank) and 61 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
945 | Yersinia infection 💬 Related to 22 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
946 | Yersinia infection 💬 Related to 22 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
947 | Yersinia infection 💬 Related to 22 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |