Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 4件: 13, 51, 67, 298 💬 |
| 2 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 1件: 67 💬 |
| 3 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
| 4 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D00349 D00349 💬 |
Isradipine | 006 1件: 6 💬 |
| 5 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
| 6 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D00437 D00437 💬 |
Nifedipine | 050 2件: 50, 81 💬 |
| 7 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 1件: 90 💬 |
| 8 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
| 9 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D08441 D08441 💬 |
Propiverine | 226 1件: 226 💬 |
| 10 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬 |
| 11 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 058 4件: 58, 96, 140, 167 💬 |
| 12 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CDK4 1件: CDK4 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 1件: 34 💬 |
| 13 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 1件: 299 💬 |
| 14 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 1件: 299 💬 |
| 15 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 1件: 299 💬 |
| 16 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 1件: 299 💬 |
| 17 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 1件: 299 💬 |
| 18 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 1件: 299 💬 |
| 19 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
ERBB2 1件: ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 20 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
ERBB2 1件: ERBB2 💬 |
D08950 D08950 💬 |
Neratinib | 034 1件: 34 💬 |
| 21 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
ERBB2 1件: ERBB2 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 1件: 67 💬 |
| 22 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
| 23 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
| 24 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
PRKCE 1件: PRKCE 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 1件: 97 💬 |
| 25 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
| 26 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
ROCK2 1件: ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 2件: 51, 85 💬 |
| 27 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
SRC 1件: SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 2件: 2 , 67 💬 |
| 28 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
SRC 1件: SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 29 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
SRC 1件: SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 30 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
SRC 1件: SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 3件: 6 , 89, 272 💬 |