Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ABCC8 2件: ABCC8, KCNJ11 💬 |
D00294 D00294 💬 |
Diazoxide | 013 2件: 13, 193 💬 |
2 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ABCC8 2件: ABCC8, KCNJ11 💬 |
D00418 D00418 💬 |
Minoxidil | 179 1件: 179 💬 |
3 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ABCC8 2件: ABCC8, KCNJ11 💬 |
D00594 D00594 💬 |
Repaglinide | 006 4件: 6 , 21, 46, 299 💬 |
4 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
5 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 3件: 8 , 46, 210 💬 |
6 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 4件: 13, 51, 67, 298 💬 |
7 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 1件: 67 💬 |
8 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
9 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 1件: 6 💬 |
10 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
11 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 2件: 50, 81 💬 |
12 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 1件: 90 💬 |
13 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
14 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬 |
15 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 4件: 58, 96, 140, 167 💬 |
16 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C 5件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM3 💬 |
D08441 D08441 💬 |
Propiverine | 226 1件: 226 💬 |
17 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
18 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 1件: 156 💬 |
19 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D07667 D07667 💬 |
Cevimeline | 053 1件: 53 💬 |
20 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
21 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D03654 D03654 💬 |
Darifenacin | 006 2件: 6 , 13 💬 |
22 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D07226 D07226 💬 |
Fesoterodine | 006 1件: 6 💬 |
23 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00465 D00465 💬 |
Oxybutynin | 006 3件: 6 , 13, 53 💬 |
24 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
25 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00138 D00138 💬 |
Scopolamine | 002 1件: 2 💬 |
26 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D08522 D08522 💬 |
Solifenacin | 006 3件: 6 , 13, 53 💬 |
27 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
28 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D08638 D08638 💬 |
Trihexyphenidyl | 005 2件: 5 , 6 💬 |
29 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00397 D00397 💬 |
Tropicamide | 006 1件: 6 💬 |
30 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D09889 D09889 💬 |
Dulaglutide | 013 2件: 13, 299 💬 |
31 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D04121 D04121 💬 |
Exenatide | 006 6件: 6 , 17, 72, 78, 193, 233 💬 |
32 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D06404 D06404 💬 |
Liraglutide | 006 3件: 6 , 75, 193 💬 |
33 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D09729 D09729 💬 |
Lixisenatide | 006 1件: 6 💬 |
34 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D10025 D10025 💬 |
Semaglutide | 006 1件: 6 💬 |
35 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D11360 D11360 💬 |
Tirzepatide | 233 1件: 233 💬 |
36 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
KCNJ11 1件: KCNJ11 💬 |
D02910 D02910 💬 |
Amiodarone | 028 2件: 28, 127 💬 |
37 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
PRKCB 1件: PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 1件: 168 💬 |
38 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 14件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬 |
39 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
SNAP25 1件: SNAP25 💬 |
D02735 D02735 💬 |
Botulinum toxin type B | 002 4件: 2 , 6 , 13, 51 💬 |