Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Alcoholism 💬
1件: ADORA2A 💬 D00528 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
2 Alcoholism 💬
1件: ADORA2A 💬 D01453 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
3 Alcoholism 💬
1件: ADORA2A 💬 D04641 💬 Istradefylline 1件:  6  💬
4 Alcoholism 💬
1件: ADORA2A 💬 D09717 💬 Preladenant 1件:  6  💬
5 Alcoholism 💬
1件: ADORA2A 💬 D05711 💬 Regadenoson 1件: 58 💬
6 Alcoholism 💬
1件: ADORA2A 💬 D12568 💬 Regadenoson 1件: 58 💬
7 Alcoholism 💬
1件: ADORA2A 💬 D10174 💬 Tozadenant 1件:  6  💬
8 Alcoholism 💬
2件: ADORA2A, ADORA2B 💬 D00045 💬 Adenosine 3件: 13, 58, 65 💬
9 Alcoholism 💬
2件: ADORA2A, ADORA2B 💬 D02769 💬 Adenosine phosphate 1件: 46 💬
10 Alcoholism 💬
1件: ADORA2B 💬 D00227 💬 Aminophylline 1件: 63 💬
11 Alcoholism 💬
1件: ADORA2B 💬 D00371 💬 Theophylline 2件: 236, 299 💬
12 Alcoholism 💬
1件: ADORA2B 💬 D06103 💬 Theophylline 2件: 236, 299 💬
13 Alcoholism 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
14 Alcoholism 💬
2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
15 Alcoholism 💬
1件: DDC 💬 D03082 💬 Benserazide 1件:  6  💬
16 Alcoholism 💬
1件: DDC 💬 D00558 💬 Carbidopa 7件:  6 , 13, 17, 90, 140, 164, 201 💬
17 Alcoholism 💬
1件: DRD1 💬 D11431 💬 Tavapadon 1件:  6  💬
18 Alcoholism 💬
2件: DRD1, DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
19 Alcoholism 💬
2件: DRD1, DRD2 💬 D09886 💬 Dexpramipexole 1件:  2  💬
20 Alcoholism 💬
2件: DRD1, DRD2 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
21 Alcoholism 💬
2件: DRD1, DRD2 💬 D01044 💬 Flupentixol 1件: 97 💬
22 Alcoholism 💬
2件: DRD1, DRD2 💬 D11839 💬 Foslevodopa 1件:  6  💬
23 Alcoholism 💬
2件: DRD1, DRD2 💬 D00059 💬 Levodopa 6件:  6 , 17, 90, 140, 164, 201 💬
24 Alcoholism 💬
2件: DRD1, DRD2 💬 D08339 💬 Pergolide 1件:  6  💬
25 Alcoholism 💬
1件: DRD2 💬 D01164 💬 Aripiprazole 2件:  6 , 206 💬
26 Alcoholism 💬
1件: DRD2 💬 D03165 💬 Bromocriptine 2件:  6 , 74 💬
27 Alcoholism 💬
1件: DRD2 💬 D07593 💬 Buspirone 2件:  6 , 51 💬
28 Alcoholism 💬
1件: DRD2 💬 D00987 💬 Cabergoline 3件:  6 , 74, 75 💬
29 Alcoholism 💬
1件: DRD2 💬 D09997 💬 Cariprazine 1件: 21 💬
30 Alcoholism 💬
1件: DRD2 💬 D00270 💬 Chlorpromazine 1件: 254 💬
31 Alcoholism 💬
1件: DRD2 💬 D01745 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬
32 Alcoholism 💬
1件: DRD2 💬 D07868 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬
33 Alcoholism 💬
1件: DRD2 💬 D00136 💬 Haloperidol 1件:  8  💬
34 Alcoholism 💬
1件: DRD2 💬 D02666 💬 Iloperidone 1件:  6  💬
35 Alcoholism 💬
1件: DRD2 💬 D08132 💬 Lisuride 2件:  6 , 86 💬
36 Alcoholism 💬
1件: DRD2 💬 D07309 💬 Melperone 1件:  6  💬
37 Alcoholism 💬
1件: DRD2 💬 D00726 💬 Metoclopramide 2件: 46, 51 💬
38 Alcoholism 💬
1件: DRD2 💬 D00454 💬 Olanzapine 2件:  2 ,  8  💬
39 Alcoholism 💬
1件: DRD2 💬 D09397 💬 Pardoprunox 1件:  6  💬
40 Alcoholism 💬
1件: DRD2 💬 D00560 💬 Pimozide 1件:  2  💬
41 Alcoholism 💬
1件: DRD2 💬 D07305 💬 Piribedil 1件:  6  💬
42 Alcoholism 💬
1件: DRD2 💬 D05575 💬 Pramipexole 3件:  2 ,  6 , 20 💬
43 Alcoholism 💬
1件: DRD2 💬 D09953 💬 Pridopidine 3件:  2 ,  6 ,  8  💬
44 Alcoholism 💬
1件: DRD2 💬 D08456 💬 Quetiapine 2件:  6 , 13 💬
45 Alcoholism 💬
1件: DRD2 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
46 Alcoholism 💬
1件: DRD2 💬 D08489 💬 Ropinirole 4件:  2 ,  6 , 74, 309 💬
47 Alcoholism 💬
1件: DRD2 💬 D05768 💬 Rotigotine 1件:  6  💬
48 Alcoholism 💬
1件: DRD2 💬 D01226 💬 Sulpiride 2件:  6 , 70 💬
49 Alcoholism 💬
1件: DRD2 💬 D01348 💬 Terguride 2件: 51, 86 💬
50 Alcoholism 💬
1件: DRD2 💬 D08590 💬 Tiapride 1件:  8  💬
51 Alcoholism 💬
1件: DRD2 💬 D01448 💬 Trifluoperazine 2件: 283, 284 💬
52 Alcoholism 💬
1件: DRD2 💬 D08636 💬 Trifluoperazine 2件: 283, 284 💬
53 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07058 💬 Acamprosate 2件:  6 , 206 💬
54 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
55 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
56 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
57 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
58 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine 1件:  8  💬
59 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
60 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
61 Alcoholism 💬
11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 D06320 💬 Vorinostat 2件: 75, 96 💬
62 Alcoholism 💬
1件: MAOA 💬 D02561 💬 Moclobemide 1件:  6  💬
63 Alcoholism 💬
2件: MAOA, MAOB 💬 D02579 💬 Iproniazid 1件:  6  💬
64 Alcoholism 💬
2件: MAOA, MAOB 💬 D08349 💬 Phenelzine 1件:  6  💬
65 Alcoholism 💬
3件: MAOA, MAOB, SLC6A3 💬 D05458 💬 Phentermine 1件: 97 💬
66 Alcoholism 💬
1件: MAOB 💬 D08469 💬 Rasagiline 6件:  2 ,  5 ,  6 , 17, 58, 66 💬
67 Alcoholism 💬
1件: MAOB 💬 D10829 💬 Rasagiline 6件:  2 ,  5 ,  6 , 17, 58, 66 💬
68 Alcoholism 💬
1件: MAOB 💬 D10158 💬 Safinamide 2件:  6 , 17 💬
69 Alcoholism 💬
1件: MAOB 💬 D03731 💬 Selegiline 1件:  6  💬
70 Alcoholism 💬
1件: MAP2K1 💬 D10604 💬 Binimetinib 1件: 34 💬
71 Alcoholism 💬
1件: MAP2K1 💬 D10405 💬 Cobimetinib 1件: 280 💬
72 Alcoholism 💬
1件: MAP2K1 💬 D11675 💬 Mirdametinib 1件: 34 💬
73 Alcoholism 💬
1件: MAP2K1 💬 D09666 💬 Selumetinib 1件: 34 💬
74 Alcoholism 💬
1件: MAP2K1 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
75 Alcoholism 💬
1件: SLC18A2 💬 D10701 💬 Deutetrabenazine 1件:  8  💬
76 Alcoholism 💬
1件: SLC18A2 💬 D08575 💬 Tetrabenazine 1件:  8  💬
77 Alcoholism 💬
1件: SLC18A2 💬 D10675 💬 Valbenazine 1件:  8  💬
78 Alcoholism 💬
1件: SLC6A3 💬 D03215 💬 Armodafinil 3件:  6 , 13, 84 💬
79 Alcoholism 💬
1件: SLC6A3 💬 D07591 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
80 Alcoholism 💬
1件: SLC6A3 💬 D08130 💬 Lisdexamfetamine 1件: 13 💬
81 Alcoholism 💬
1件: SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬