Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D10893 D10893 💬 |
Acalabrutinib | 046 2件: 46, 61 💬 |
2 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D11478 D11478 💬 |
Branebrutinib | 046 3件: 46, 49, 53 💬 |
3 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D12467 D12467 💬 |
Evobrutinib | 013 3件: 13, 46, 49 💬 |
4 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D11457 D11457 💬 |
Fenebrutinib | 013 1件: 13 💬 |
5 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D10223 D10223 💬 |
Ibrutinib | 028 3件: 28, 60, 61 💬 |
6 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 |
7 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D12285 D12285 💬 |
Remibrutinib | 013 2件: 13, 53 💬 |
8 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK 1件: BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 |
9 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD19 1件: CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 4件: 11, 13, 51, 300 💬 |
10 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD19 1件: CD19 💬 |
D11496 D11496 💬 |
Obexelimab | 300 1件: 300 💬 |
11 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD3D 2件: CD3D, CD3E 💬 |
D08959 D08959 💬 |
Otelixizumab | 046 1件: 46 💬 |
12 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD3D 2件: CD3D, CD3E 💬 |
D06314 D06314 💬 |
Visilizumab | 096 2件: 96, 97 💬 |
13 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD3E 1件: CD3E 💬 |
D11463 D11463 💬 |
Mosunetuzumab | 049 1件: 49 💬 |
14 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD4 1件: CD4 💬 |
D06356 D06356 💬 |
Zanolimumab | 046 1件: 46 💬 |
15 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40 1件: CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 1件: 222 💬 |
16 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40 1件: CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 2件: 49, 53 💬 |
17 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40 1件: CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 2件: 53, 97 💬 |
18 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
19 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
IL2RG 1件: IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
20 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
JAK3 1件: JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 1件: 46 💬 |
21 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
JAK3 1件: JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
22 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
LCK 1件: LCK 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
23 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
LCK 1件: LCK 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
24 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
TNFRSF13C 1件: TNFRSF13C 💬 |
D12151 D12151 💬 |
Ianalumab | 035 7件: 35, 46, 49, 53, 61, 63, 95 💬 |