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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(RS)-baclofen[1] Baclofen[1] D00241 [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 10
2(RS)-baclofen, naltrexone hydrochloride and D-sorbitol[3] Baclofen,
Naltrexone,
Sorbitol		[3] D00096 ,
D00241 ,
D05113 		[5] GABBR1,
GABBR2,
OPRD1,
OPRK1,
OPRM1 💬		[9] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 10
3ACE-083----[2] 10, 113
4Acetate[1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299
5ACIDO ASCORBICO----[1] 10
6ACIDO ASCORBICO DC.IT----[1] 10
7Ascorbic acid[1] Ascorbic acid[1] D00018 --[4] 10, 97, 206, 298
8Ascorbic acid (Vitamin C)[1] Ascorbic acid[1] D00018 --[1] 10
9Ascorbic acid vit C[1] Ascorbic acid[1] D00018 --[1] 10
10Baclofen[1] Baclofen[1] D00241 [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[8] 2, 10, 13, 18, 65, 70, 149, 206
11BACLOFENE----[1] 10
12BIOTIN[1] Biotin[1] D00029 --[5] 2, 8, 10, 13, 20
13CEBION 500*20CPR MAST 500MG----[1] 10
14CEBION 500MG 20CPR MAST.ARAN----[1] 10
15Coenzyme Q10[1] Ubidecarenone[1] D01065 --[11] 2, 5, 6, 8, 10, 18, 46, 57, 113, 214, 215
16D-BIOTIN[1] Biotin[1] D00029 --[3] 10, 13, 20
17D-SORBITOL[1] Sorbitol[1] D00096 --[1] 10
18ElleOne----[1] 10
19EN001----[2] 10, 113
20Engensis (VM202)----[1] 10
21FLX-787-ODT (orally disintegrating tablet)----[1] 10
22MD1003----[5] 2, 10, 13, 14, 20
23Mexiletine[1] Mexiletine[1] D08215 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 1, 2, 10, 113, 114
24Naltrexone[1] Naltrexone[1] D05113 [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226
25NALTREXONE CLORIDRATO[1] Naltrexone[1] D05113 [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 10
26NALTREXONE HYDROCHLORIDE[1] Naltrexone[1] D05113 [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[8] 10, 40, 41, 42, 43, 44, 45, 96
27Non applicable----[2] 10, 19
28PXT3003----[1] 10
29PXT3003 Dose 1----[1] 10
30PXT3003 Dose 2----[1] 10
31PXT3003 Dose 2 (equivalent to twice Dose 1)----[1] 10
32PXT3003 High Dose----[1] 10
33PXT3003 Intermediate Dose----[1] 10
34PXT3003 Low dose----[1] 10
35RS-BACLOFEN[1] Baclofen[1] D00241 [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 10
36SODIO ASCORBATO DC.IT----[1] 10
37Sorbitol[1] Sorbitol[1] D00096 --[1] 10
38SORBITOLO----[1] 10
39Ulipristal[1] Ulipristal[1] D09567 [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 10
40ULIPRISTAL ACETATE[2] Acetate,
Ulipristal		[1] D09567 [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 10
41Vitamin C[1] Ascorbic acid[1] D00018 --[6] 10, 192, 206, 210, 211, 212