113. 筋ジストロフィー Muscular dystrophy Clinical trials / Disease details
臨床試験数 : 646 / 薬物数 : 471 - (DrugBank : 105) / 標的遺伝子数 : 59 - 標的パスウェイ数 : 170
Showing 1 to 10 of 12 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT02836418 (ClinicalTrials.gov) | July 12, 2016 | 30/6/2016 | Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940 in Patients With Limb Girdle and Facioscapulohumeral Muscular Dystrophy Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940in Patients ... | An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940 in Patients With Limb Girdle and Facioscapulohumeral Muscular Dystrophy An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activit ... | Facioscapulohumeral Muscular Dystrophy;Limb Girdle Muscular Dystrophy | Drug: ATYR1940 | aTyr Pharma, Inc. | NULL | Completed | 16 Years | 25 Years | All | 8 | Phase 1/Phase 2 | United States;Denmark;Italy |
2 | EUCTR2016-000624-25-DK (EUCTR) | 22/06/2016 | 19/04/2016 | An Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940 in Patients with Limb Girdle and Fascioscapulohumeral Muscular Dystrophy An Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940in Patie ... | An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940 in Patients with Limb Girdle and Fascioscapulohumeral Muscular Dystrophy An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activit ... | Limb Girdle Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy MedDRA version: 19.0;Level: PT;Classification code 10064087;Term: Facioscapulohumeral muscular dystrophy;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05] Limb Girdle Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy MedDRA version: 19.0;Level ... | Product Name: ATYR1940 Product Code: ATYR1940 INN or Proposed INN: Not available yet Other descriptive name: ATYR1940 Product Name: ATYR1940 Product Code: ATYR1940 INN or Proposed INN: Not available yet Other descriptive ... | aTyr Pharma, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 22 | Phase 1;Phase 2 | United States;Denmark;Italy | ||
3 | NCT02603562 (ClinicalTrials.gov) | March 30, 2016 | 5/11/2015 | Evaluate Safety and Biological Activity of ATYR1940 in Patients With Early Onset Facioscapulohumeral Muscular Dystrophy Evaluate Safety and Biological Activity of ATYR1940in Patients With Early Onset Facioscapulohumeral ... | An Open-Label, Intrapatient Dose-Escalation Study to Evaluate the Safety, Tolerability, Immunogenicity, and Biological Activity of ATYR1940 in Patients With Early Onset and Other Pediatric Onset Facioscapulohumeral Muscular Dystrophy An Open-Label, Intrapatient Dose-Escalation Study to Evaluate the Safety, Tolerability, Immunogenici ... | Facioscapulohumeral Muscular Dystrophy (FSHD) | Biological: ATYR1940;Biological: Placebo | aTyr Pharma, Inc. | NULL | Completed | 12 Years | 25 Years | All | 8 | Phase 1/Phase 2 | United States;France;Italy |
4 | EUCTR2015-001910-88-DK (EUCTR) | 17/12/2015 | 30/06/2015 | A Study to Evaluate the Safety, Tolerability, Immunogenicity, and Biological Activity of ATYR1940 in Patients with Limb Girdle and Facioscapulohumeral Muscular Dystrophies A Study to Evaluate the Safety, Tolerability, Immunogenicity, and Biological Activity of ATYR1940in ... | An Open-Label, Intrapatient Dose Escalation Study to Evaluate the Safety, Tolerability, Immunogenicity, and Biological Activity of ATYR1940 in Patients with Limb Girdle and Facioscapulohumeral Muscular Dystrophies An Open-Label, Intrapatient Dose Escalation Study to Evaluate the Safety, Tolerability, Immunogenici ... | Limb Girdle Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy MedDRA version: 19.0;Level: PT;Classification code 10064087;Term: Facioscapulohumeral muscular dystrophy;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05] Limb Girdle Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy MedDRA version: 19.0;Level ... | Product Name: ATYR1940 Product Code: ATYR1940 INN or Proposed INN: Not available yet | aTyr Pharma, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 16 | Phase 1;Phase 2 | France;United States;Denmark;Italy | ||
5 | NCT02579239 (ClinicalTrials.gov) | November 5, 2015 | 28/9/2015 | The Safety and Biological Activity of ATYR1940 in Patients With Limb Girdle or Facioscapulohumeral Muscular Dystrophies The Safety and Biological Activity of ATYR1940in Patients With Limb Girdle or Facioscapulohumeral Mu ... | An Open-Label, Intrapatient Dose Escalation Study to Evaluate the Safety, Tolerability, Immunogenicity, and Biological Activity of ATYR1940 in Patients With Limb Girdle and Facioscapulohumeral Muscular Dystrophies An Open-Label, Intrapatient Dose Escalation Study to Evaluate the Safety, Tolerability, Immunogenici ... | Limb-Girdle Muscular Dystrophies;Facioscapulohumeral Muscular Dystrophy | Biological: ATYR1940;Biological: Placebo | aTyr Pharma, Inc. | NULL | Completed | 18 Years | 75 Years | All | 18 | Phase 1/Phase 2 | United States;Denmark;France;Italy |
6 | NCT02531217 (ClinicalTrials.gov) | September 2015 | 25/6/2015 | Safety, Tolerability, PK, and Activity of ATYR1940 in Patients With Muscular Dystrophy - Study Extension Safety, Tolerability, PK, and Activity of ATYR1940in Patients With Muscular Dystrophy - Study Extens ... | An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, Biological Activity, and Systemic Exposure of ATYR1940 in Adult Patients With Fascioscapulohumeral Muscular Dystrophy (FSHD) An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, Biological Activity, a ... | Facioscapulohumeral Muscular Dystrophy | Biological: ATYR1940 | aTyr Pharma, Inc. | NULL | Completed | 18 Years | 65 Years | All | 9 | Phase 1/Phase 2 | United States;Italy;Netherlands |
7 | EUCTR2015-001912-36-NL (EUCTR) | 04/08/2015 | 22/06/2015 | A Study to Evaluate the Long-Term Safety, Tolerability, Biological Activity, and Exposure of ATYR1940 in Adult Patients with Genetic Myopathy A Study to Evaluate the Long-Term Safety, Tolerability, Biological Activity, and Exposure of ATYR194 ... | An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, Biological Activity, and Systemic Exposure of ATYR1940 in Adult Patients with Facioscapulohumeral Muscular Dystrophy (FSHD) An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, Biological Activity, a ... | Facioscapulohumeral muscular dystrophy MedDRA version: 19.0;Level: PT;Classification code 10064087;Term: Facioscapulohumeral muscular dystrophy;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05] Facioscapulohumeral muscular dystrophy MedDRA version: 19.0;Level: PT;Classification code 10064087;T ... | Product Name: ATYR1940 Product Code: ATYR1940 INN or Proposed INN: Not available yet Other descriptive name: ATYR1940 Product Name: ATYR1940 Product Code: ATYR1940 INN or Proposed INN: Not available yet Other descriptive ... | aTyr Pharma, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 32 | Phase 1;Phase 2 | United States;Netherlands;Italy | ||
8 | EUCTR2014-001753-17-NL (EUCTR) | 19/09/2014 | 03/06/2014 | A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biological Activity of ATYR1940 in Adults with Genetic Myopathy A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biological Activity of ATYR1940in ... | A Placebo-Controlled, Randomized, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Biological Activity of ATYR1940 in Adult Patients with Molecularly Defined Genetic Muscular Dystrophies A Placebo-Controlled, Randomized, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability ... | Facioscapulohumeral muscular dystrophy MedDRA version: 17.1;Level: PT;Classification code 10064087;Term: Facioscapulohumeral muscular dystrophy;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05] Facioscapulohumeral muscular dystrophy MedDRA version: 17.1;Level: PT;Classification code 10064087;T ... | Product Name: ATYR1940 Product Code: ATYR1940 INN or Proposed INN: N/A | aTyr Pharma, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 44 | Phase 1;Phase 2 | United States;France;Netherlands;Italy | ||
9 | NCT02239224 (ClinicalTrials.gov) | August 2014 | 7/9/2014 | Safety, Tolerability, Pharmacokinetics, and Biological Activity of ATYR1940 in Adult Patients With Muscular Dystrophy Safety, Tolerability, Pharmacokinetics, and Biological Activity of ATYR1940in Adult Patients With Mu ... | A Placebo-Controlled, Randomized, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Biological Activity of ATYR1940 in Adult Patients With Molecularly Defined Genetic Muscular Dystrophies A Placebo-Controlled, Randomized, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability ... | Facioscapulohumeral Muscular Dystrophy (FSHD) | Biological: Placebo;Biological: ATYR1940 | aTyr Pharma, Inc. | NULL | Completed | 18 Years | 65 Years | All | 20 | Phase 1/Phase 2 | United States;France;Italy;Netherlands |
10 | EUCTR2014-001753-17-IT (EUCTR) | 30/07/2014 | 13/06/2014 | A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biological Activity of ATYR1940 in Adults with Genetic Myopathy A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biological Activity of ATYR1940in ... | A Placebo-Controlled, Randomized, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Biological Activity of ATYR1940 in Adult Patients with Molecularly Defined Genetic Muscular Dystrophies A Placebo-Controlled, Randomized, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability ... | Facioscapulohumeral muscular dystrophy MedDRA version: 17.0;Level: PT;Classification code 10064087;Term: Facioscapulohumeral muscular dystrophy;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05] Facioscapulohumeral muscular dystrophy MedDRA version: 17.0;Level: PT;Classification code 10064087;T ... | Product Name: ATYR1940 Product Code: ATYR1940 INN or Proposed INN: N/A | aTyr Pharma, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 44 | Phase 1;Phase 2 | United States;France;Netherlands;Italy |