13. 多発性硬化症／視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

33 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2020-000644-55-DE (EUCTR)	22/04/2021	17/06/2020	Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's TyrosineKinase (BTK) Inhibitor Tolebru ...	A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide ( ...	Relapsing Multiple Sclerosis MedDRA version: 21.0;Level: PT;Classification code 10080700;Term: Relap ...	Product Code: SAR442168 INN or Proposed INN: Not available Other descriptive name: PRN2246 Trade Name: ...	Genzyme Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1200	Phase 3	United States;Serbia;Portugal;Slovakia;Greece;Spain;Ukraine;Russian Federation;Israel;Chile;Switzerl ...
2	EUCTR2020-000637-41-AT (EUCTR)	16/02/2021	09/09/2020	Relapsing Forms of multiple sclerosis (RMS) study of Bruton's TyrosineKinase (BTK) inhibitor Tolebru ...	A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide ( ...	Relapsing Multiple Sclerosis MedDRA version: 21.0;Level: PT;Classification code 10080700;Term: Relap ...	Product Code: SAR442168 INN or Proposed INN: Not available Other descriptive name: PRN2246 Trade Name: ...	Genzyme Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1200	Phase 3	United States;Belarus;Estonia;Taiwan;Hong Kong;Spain;Ukraine;Russian Federation;Italy;Denmark;China; ...
3	EUCTR2020-000644-55-FR (EUCTR)	22/12/2020	15/06/2020	RMS study of BTK inhibitor SAR442168 (GEMINI 2)	A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide ( ...	Relapsing Multiple Sclerosis MedDRA version: 21.0;Level: PT;Classification code 10080700;Term: Relap ...	Product Code: SAR442168 INN or Proposed INN: Not available Other descriptive name: PRN2246 Trade Name: ...	Genzyme Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1200	Phase 3	United States;Portugal;Serbia;Slovakia;Greece;Spain;Ukraine;Israel;Chile;Russian Federation;Switzerl ...
4	EUCTR2020-000644-55-HU (EUCTR)	11/12/2020	12/10/2020	Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebr ...	A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide ( ...	Relapsing Multiple Sclerosis MedDRA version: 21.0;Level: PT;Classification code 10080700;Term: Relap ...	Product Code: SAR442168 INN or Proposed INN: Not available Other descriptive name: PRN2246 Trade Name: ...	Genzyme Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1200	Phase 3	United States;Serbia;Portugal;Slovakia;Greece;Spain;Ukraine;Russian Federation;Israel;Chile;Switzerl ...
5	EUCTR2020-000644-55-PT (EUCTR)	23/11/2020	17/09/2020	RMS study of BTK inhibitor SAR442168 (GEMINI 2)	A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide ( ...	Relapsing Multiple Sclerosis MedDRA version: 21.0;Level: PT;Classification code 10080700;Term: Relap ...	Product Code: SAR442168 INN or Proposed INN: Not available Other descriptive name: PRN2246 Trade Name: ...	Genzyme Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1200	Phase 3	United States;Serbia;Portugal;Slovakia;Greece;Spain;Ukraine;Russian Federation;Israel;Chile;Switzerl ...
6	EUCTR2020-000637-41-FI (EUCTR)	19/11/2020	07/09/2020	Relapsing Forms of multiple sclerosis (RMS) study of Bruton's Tyrosine Kinase (BTK) inhibitor Tolebr ...	A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide ( ...	Relapsing Multiple Sclerosis MedDRA version: 21.0;Level: PT;Classification code 10080700;Term: Relap ...	Product Code: SAR442168 INN or Proposed INN: Not available Other descriptive name: PRN2246 Trade Name: ...	Genzyme Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1200	Phase 3	United States;Belarus;Estonia;Taiwan;Hong Kong;Spain;Ukraine;Russian Federation;Italy;Denmark;China; ...
7	EUCTR2020-000644-55-NL (EUCTR)	09/11/2020	10/09/2020	Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebr ...	A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide ( ...	Relapsing Multiple Sclerosis MedDRA version: 21.0;Level: PT;Classification code 10080700;Term: Relap ...	Product Code: SAR442168 INN or Proposed INN: Not available Other descriptive name: PRN2246 Trade Name: ...	Genzyme Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1200	Phase 3	United States;Serbia;Portugal;Slovakia;Greece;Spain;Ukraine;Chile;Israel;Russian Federation;Switzerl ...
8	EUCTR2020-000637-41-CZ (EUCTR)	05/11/2020	03/09/2020	Relapsing Forms of multiple sclerosis (RMS) study of Bruton's Tyrosine Kinase (BTK) inhibitor Tolebr ...	A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide ( ...	Relapsing Multiple Sclerosis MedDRA version: 21.0;Level: PT;Classification code 10080700;Term: Relap ...	Product Code: SAR442168 INN or Proposed INN: Not available Other descriptive name: PRN2246 Trade Name: ...	Genzyme Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1200	Phase 3	United States;Belarus;Taiwan;Hong Kong;Estonia;Spain;Ukraine;Russian Federation;Italy;Denmark;China; ...
9	EUCTR2020-000637-41-PL (EUCTR)	23/10/2020	23/10/2020	Relapsing Forms of multiple sclerosis (RMS) study of Bruton's Tyrosine Kinase (BTK) inhibitor Tolebr ...	A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide ( ...	Relapsing Multiple Sclerosis MedDRA version: 21.0;Level: PT;Classification code 10080700;Term: Relap ...	Product Code: SAR442168 INN or Proposed INN: Not available Other descriptive name: PRN2246 Trade Name: ...	Genzyme Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1200	Phase 3	Belarus;United States;Hong Kong;Estonia;Taiwan;Spain;Ukraine;Russian Federation;Italy;Denmark;China; ...
10	EUCTR2020-000637-41-LT (EUCTR)	22/10/2020	09/09/2020	Relapsing Forms of multiple sclerosis (RMS) study of Bruton's Tyrosine Kinase (BTK) inhibitor Tolebr ...	A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide ( ...	Relapsing Multiple Sclerosis MedDRA version: 21.0;Level: PT;Classification code 10080700;Term: Relap ...	Product Code: SAR442168 INN or Proposed INN: Not available Other descriptive name: PRN2246 Trade Name: ...	Genzyme Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1200	Phase 3	Belarus;United States;Estonia;Hong Kong;Taiwan;Spain;Ukraine;Russian Federation;Italy;Denmark;China; ...

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