13. 多発性硬化症／視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

6 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04660539 (ClinicalTrials.gov)	March 2, 2021	24/11/2020	A Study to Evaluate the Safety and Efficacy of Satralizumab in Participants With Neuromyelitis Optic ...	A Multicenter, Single Arm, Open-Label Study to Evaluate the Long-Term Safety and Efficacy of Satrali ...	Neuromyelitis Optica Spectrum Disorder	Drug: satralizumab;Drug: azathioprine (AZA);Drug: mycophenolate mofetil (MMF);Drug: oral corticosteroid ...	Hoffmann-La Roche	NULL	Active, not recruiting	18 Years	N/A	All	119	Phase 3	United States;Bulgaria;Canada;Croatia;Germany;Hungary;Italy;Japan;Korea, Republic of;Malaysia;Poland ...
2	ChiCTR1900025744	2019-09-01	2019-09-07	Clinical effectiveness and safety of Rituximab (Henlius) for optic neuritis secondary to neuromyelit ...	Clinical effectiveness and safety Rituximab (Henlius) for optic neuritis secondary to neuromyelitis ...	neuromyelitis optica spectrum disorder (NMOSD)	1:Intravenous 200mg Rituximab, 1/week*2, if the proportion of CD19+ B lymphocytes in peripheral bloo ...	The Ophthalmology Department of the Chinese Peoples Liberation Army Hospital	NULL	Recruiting	18	70	Both	1:30;2:30;	Phase 4	China
3	NCT03350633 (ClinicalTrials.gov)	November 1, 2017	10/11/2017	Tocilizumab vs Azathioprine in Neuromyelitis Optica Spectrum Disorders	Safety and Efficacy of Tocilizumab Versus Azathioprinein Neuromyelitis Optica Spectrum Disorders: a ...	Neuromyelitis Optica Spectrum Disorders;Neuromyelitis Optica	Drug: Tocilizumab Injection;Drug: Azathioprine	Tianjin Medical University General Hospital	NULL	Completed	18 Years	N/A	All	118	Phase 2/Phase 3	China
4	NCT03002038 (ClinicalTrials.gov)	September 2015	21/12/2016	Comparison of Clinical Effects of Azathioprine and Rituximab NMO-SD Patients	Comparison of Annual Relapse Rate, Expanded Disability Status Scale, and Side Effects Between Azathi ...	Neuromyelitis Optica Spectrum Disorder	Drug: Azathioprine;Drug: Rituximab	Isfahan University of Medical Sciences	NULL	Completed	18 Years	50 Years	All	86	Phase 2/Phase 3	Iran, Islamic Republic of
5	ChiCTR-ICR-15007177	2014-08-30	2014-05-30	A Prospective Study on the Efficacy andSafety of Rituximab in Treatment for Neuromyelitis Optica ass ...	A Prospective Study on the Efficacy andSafety of Rituximab in Treatment for Neuromyelitis Optica ass ...	Neuromyelitis Optica associated Optic Neuritis	1:Intravenous 100mg Rituximab, 1/week*4 ;2:Oral azathioprine(2.5-3 mg/kg bodyweight/day) or mycophen ...	The Ophthalmology Department of the Chinese Peoples Liberation Army Hospital	NULL	Recruiting	18	70	Both	1:30;2:30;		China
6	EUCTR2006-004937-13-IT (EUCTR)	17/08/2006	04/07/2007	multicentee randomized controlled study of azathioprineversus iterferon beta in relapsing remitting ...	multicentee randomized controlled study of azathioprineversus iterferon beta in relapsing remitting ...	patients with relapsing remitting multiple sclerosis MedDRA version: 9.1;Level: LLT;Classification c ...	Trade Name: AZATIOPRINA HEX. 50CPR 50MG BL INN or Proposed INN: Azathioprine Trade Name: REBIF SC 12SIR ...	Universita di Firenze	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Italy

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