13. 多発性硬化症／視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

61 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2021-003677-66-NL (EUCTR)	14/02/2022	16/12/2021	Clemastine fumarate as a treament for eye movement disorders in patients with multiple sclerosis	Clemastine fumarate as remyelinating treatment in internuclear ophthalmoparesis and multiple scleros ...	Multiple sclerosis (MS)Internuclear ophthalmoparesis (INO) MedDRA version: 21.0;Level: LLT;Classific ...	Trade Name: Clemastine Milstein 1 mg, tabletten Product Name: Clemastine fumarate INN or Proposed INN: C ...	Amsterdam University Medical Center	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	80	Phase 3	Netherlands
2	NCT05730738 (ClinicalTrials.gov)	June 1, 2021	5/12/2021	Dalfampridine in Egyptian Patients With Multiple Sclerosis	Effect of Dalfampridineon Gait Impairment, Cognition and Fatigue in Egyptian Patients With Multiple ...	Multiple Sclerosis	Drug: Dalfampridine ER, 10 Mg Oral Tablet, Extended Release;Drug: Placebo	Ain Shams University	NULL	Recruiting	18 Years	N/A	All	100	N/A	Egypt
3	NCT03847545 (ClinicalTrials.gov)	December 12, 2018	19/12/2018	Muscle Strain in Multiple Sclerosis Patients Measured by Ultrasound Speckle Tracking Technique	Muscle Strain in Multiple Sclerosis Patients Measured by Ultrasound Speckle Tracking	Multiple Sclerosis	Drug: Fampridine	University of Southern Denmark	Odense University Hospital;Sygehus Lillebaelt;Region of Southern Denmark;The Augustinus Foundation, ...	Completed	18 Years	100 Years	All	48	N/A	Denmark
4	NCT03164018 (ClinicalTrials.gov)	March 7, 2017	29/3/2017	Fampridine in MS Patients: A Cognition, Fatigue, Depression and Quality of Life Analysis	Fampridine in MS Patients: A Cognition, Fatigue, Depression and Quality of Life Analysis	Multiple Sclerosis	Drug: Fampridine	Genesis Pharma CNS & Specialty	NULL	Completed	18 Years	N/A	All	111		Greece
5	EUCTR2014-004650-34-IT (EUCTR)	27/06/2016	05/11/2020	New strategies for diagnostic, therapeutic and clinical care in neurological diseases	Neuromodulation strategies to enhance the effects of gait rehabilitation in multiple sclerosis patie ...	Multiple sclerosis with cerebellar ataxia MedDRA version: 20.1;Level: PT;Classification code 1002824 ...	Trade Name: FAMPYRA - 10 MG - COMPRESSA A RILASCIO PROLUNGATO - USO ORALE - FLACONE (HDPE) 56 COMPRES ...	IRCCS FONDAZIONE ISTITUTO NEUROLOGICO NAZIONALE C. MONDINO	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	45	Phase 4	Italy
6	EUCTR2014-003498-41-AT (EUCTR)	22/09/2015	06/08/2015	Effects of dalfampridine on mobility in the context of daily life	Effects of dalfampridineon mobility in the context of daily life - FampridineStudy in Activities of ...	Motor behaviour and cognition in multiple sclerosis patients;Therapeutic area: Diseases [C] - Nervou ...	Trade Name: Fampyra INN or Proposed INN: FAMPRIDINE	Medical University of Vienna	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Austria
7	NCT01532154 (ClinicalTrials.gov)	August 2015	15/12/2011	Fampridine Pregnancy Exposure Registry	Fampridine Pregnancy Exposure Registry	Multiple Sclerosis;Pregnancy	Drug: Fampridine	Biogen	NULL	Terminated	N/A	N/A	Female	1	N/A	France;Germany;United Kingdom;United States
8	NCT02391961 (ClinicalTrials.gov)	April 1, 2015	3/3/2015	Study and Treatment of Visual Dysfunction and Motor Fatigue in Multiple Sclerosis	Study and Treatment of Visual Dysfunction and Motor Fatigue in Multiple Sclerosis	Multiple Sclerosis;Internuclear Ophthalmoplegia;Fatigue	Drug: Dalfampridine;Drug: Placebo	VA Office of Research and Development	NULL	Completed	18 Years	65 Years	All	23	Phase 2	United States
9	EUCTR2013-003600-40-NL (EUCTR)	20/02/2015	26/11/2014	Study to Assess the Long-Term Efficacy and Safety of Prolonged Release Fampridine(BIIB041) 10 mg, Ad ...	A Multicenter, Randomized, Double Blind, Placebo Controlled Study to Assess the Long-Term Efficacy a ...	Multiple Sclerosis MedDRA version: 18.0;Level: PT;Classification code 10028245;Term: Multiple sclero ...	Trade Name: Fampyra Product Name: Fampridine Product Code: BIIB041 INN or Proposed INN: FAMPRIDINE	Biogen Idec Research Limited	NULL	Not Recruiting			Female: yes Male: yes	590	Phase 3	Serbia;United States;Czech Republic;Finland;Poland;Lithuania;Russian Federation;Bulgaria;Netherlands ...
10	EUCTR2015-000182-31-NL (EUCTR)	11/02/2015	26/01/2015	Study to evaluate the effects of fampridinein patients with multiple sclerosis and eye movement abno ...	A randomized, double-blind, placebo-controlled, cross-over study to assess the effects of fampridine ...	Multiple sclerosis (MS) and a unilateral or bilateral internuclear ophthalmoplegia (INO);Therapeutic ...	Trade Name: Fampyra 10 mg prolonged-release tablets INN or Proposed INN: FAMPRIDINE	CHDR	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Netherlands

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