13. 多発性硬化症／視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

11 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02644044 (ClinicalTrials.gov)	January 2016	23/3/2015	Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study	Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study	To Evaluate the Effect of Therapy With IT MTX on the Disease Course of Patients With Progressive MS	Drug: Intrathecal methotrexate	Tel-Aviv Sourasky Medical Center	NULL	Not yet recruiting	18 Years	75 Years	Both	30	Phase 0	NULL
2	EUCTR2007-001377-28-PT (EUCTR)	09/01/2009	25/08/2008	Phase IV, one-day, single blood sampling study to investigate severe thrombocytopenia and autoimmune ...	Phase IV, one-day, single blood sampling study to investigate severe thrombocytopenia and autoimmune ...	Adult patients with moderate to severe chronic plaque psoriasis -- who have failed to respond to, or ...	Trade Name: Raptiva 100 mg/ml powder and solvent for solution for injection INN or Proposed INN: Efali ...	Merck Serono International S.A.	NULL	Not Recruiting			Female: yes Male: yes	92	Phase 4	Portugal;Germany;Netherlands;France;Austria
3	EUCTR2007-001377-28-DE (EUCTR)	01/09/2008	15/05/2008	Phase IV, one-day, single blood sampling study to investigate severe thrombocytopenia and autoimmune ...	Phase IV, one-day, single blood sampling study to investigate severe thrombocytopenia and autoimmune ...	Adult patients with moderate to severe chronic plaque psoriasis -- who have failed to respond to, or ...	Trade Name: Raptiva 100 mg/ml powder and solvent for solution for injection INN or Proposed INN: Efali ...	Merck Serono International S.A.	NULL	Not Recruiting			Female: yes Male: yes	92	Phase 4	Portugal;Germany;Netherlands;France;Austria
4	EUCTR2007-001377-28-NL (EUCTR)	15/07/2008	29/05/2008	Phase IV, one-day, single blood sampling study to investigate severe thrombocytopenia and autoimmune ...	Phase IV, one-day, single blood sampling study to investigate severe thrombocytopenia and autoimmune ...	Adult patients with moderate to severe chronic plaque psoriasis -- who have failed to respond to, or ...	Trade Name: Raptiva 100 mg/ml powder and solvent for solution for injection INN or Proposed INN: Efali ...	Merck Serono International S.A.	NULL	Not Recruiting			Female: yes Male: yes	92	Phase 4	Portugal;Germany;Netherlands;France;Austria
5	EUCTR2007-001377-28-AT (EUCTR)	26/06/2008	27/05/2008	Phase IV, one-day, single blood sampling study to investigate severe thrombocytopenia and autoimmune ...	Phase IV, one-day, single blood sampling study to investigate severe thrombocytopenia and autoimmune ...	Adult patients with moderate to severe chronic plaque psoriasis -- who have failed to respond to, or ...	Trade Name: Raptiva 100 mg/ml powder and solvent for solution for injection INN or Proposed INN: Efali ...	Merck Serono International S.A.	NULL	Not Recruiting			Female: yes Male: yes	92	Phase 4	Portugal;Germany;Netherlands;France;Austria
6	EUCTR2007-001377-28-FR (EUCTR)	11/06/2008	29/02/2008	Phase IV, one-day, single blood sampling study to investigate severe thrombocytopenia and autoimmune ...	Phase IV, one-day, single blood sampling study to investigate severe thrombocytopenia and autoimmune ...	Adult patients with moderate to severe chronic plaque psoriasis -- who have failed to respond to, or ...	Trade Name: Raptiva 100 mg/ml powder and solvent for solution for injection INN or Proposed INN: Efali ...	Merck Serono International S.A.	NULL	Not Recruiting			Female: yes Male: yes	92	Phase 4	Portugal;France;Austria;Netherlands;Germany
7	NCT00344253 (ClinicalTrials.gov)	March 2006	22/6/2006	Randomized, Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediat ...	A Monocentric, Randomized, Controlled Trial to Test the Efficacy of Interferon-beta in the Treatment ...	Uveitis, Intermediate;Macular Edema;Multiple Sclerosis	Drug: Interferon beta;Drug: Methotrexate	Heidelberg University	Serono GmbH	Completed	18 Years	N/A	Both	19	Phase 3	Germany
8	EUCTR2004-004403-37-DE (EUCTR)	27/02/2006	28/10/2005	Eine monozentrische, randomisierte, kontrollierte Studie zur Untersuchung von Interferon-beta zur Be ...	Eine monozentrische, randomisierte, kontrollierte Studie zur Untersuchung von Interferon-beta zur Be ...	Uveitis intermedia with inflammatory macula edema with or without associated Multiple Sclerosis	Product Name: Rebif INN or Proposed INN: Interferon beta -1a Product Name: Rebif INN or Proposed INN: In ...	Universitätsklinikum Heidelberg	NULL	Not Recruiting			Female: yes Male: yes	34	Phase 3	Germany
9	NCT00112034 (ClinicalTrials.gov)	June 2003	27/5/2005	AVONEX® Combination Trial - ACT	A Multi-Center, Randomized, Blinded, Parallel-Group Study of AVONEX Compared With AVONEX in Combinat ...	Multiple Sclerosis, Relapsing-Remitting	Drug: Methotrexate;Drug: IV methylprednisolone	Biogen Idec	NULL	Completed	18 Years	55 Years	Both	350	Phase 4	United States
10	NCT00037115 (ClinicalTrials.gov)	May 2002	15/5/2002	Induction Therapy With a Single High Dose Bolus of Intravenous MethotrexateWith Leucovorin Rescue, P ...	An Open Label Pilot Study of Induction Therapy With a Single High Dose Bolus of Intravenous Methotre ...	Demyelinating Disorders;Multiple Sclerosis;Optic Neuritis;Myelitis;Neuritis	Drug: interferon beta 1a;Drug: methotrexate;Drug: methylprednisolone	MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute	Consultants in Neurology	Withdrawn	18 Years	50 Years	All	0	Phase 4	United States

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