13. 多発性硬化症／視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

12 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR2100051105	2021-09-23	2021-09-13	Correlation between IMPDH and SLCO1B polymorphisms and the efficacy and safety of mycophenolate mofe ...	Correlation between IMPDH and SLCO1B polymorphisms and the efficacy and safety of mycophenolate mofe ...	Neuromyelitis optica spectrum disorders (NMOSD)	Intervention Group:MMF treatment;	Huashan Hospital, Fudan University	NULL	Recruiting	18	75	Both	Intervention Group:200;	N/A	China
2	NCT04660539 (ClinicalTrials.gov)	March 2, 2021	24/11/2020	A Study to Evaluate the Safety and Efficacy of Satralizumab in Participants With Neuromyelitis Optic ...	A Multicenter, Single Arm, Open-Label Study to Evaluate the Long-Term Safety and Efficacy of Satrali ...	Neuromyelitis Optica Spectrum Disorder	Drug: satralizumab;Drug: azathioprine (AZA);Drug: mycophenolate mofetil(MMF);Drug: oral corticosteroid ...	Hoffmann-La Roche	NULL	Active, not recruiting	18 Years	N/A	All	119	Phase 3	United States;Bulgaria;Canada;Croatia;Germany;Hungary;Italy;Japan;Korea, Republic of;Malaysia;Poland ...
3	ChiCTR2100043013	2021-01-31	2021-02-04	Efficacy difference between low dose rituximab and mycophenolate mofetilin preventing recurrence of ...	Efficacy difference between low dose rituximab and mycophenolate mofetilin preventing recurrence of ...	Neuromyelitis optica spectrum diseases	low dose rituximab group: low dose rituximab ;mycophenolate mofetil group:mycophenolate mofetil ;	Shandong University Qilu Hospital	NULL	Pending			Both	low dose rituximab group:30;mycophenolate mofetil group:30;	Phase 4	China
4	ChiCTR1900025744	2019-09-01	2019-09-07	Clinical effectiveness and safety of Rituximab (Henlius) for optic neuritis secondary to neuromyelit ...	Clinical effectiveness and safety Rituximab (Henlius) for optic neuritis secondary to neuromyelitis ...	neuromyelitis optica spectrum disorder (NMOSD)	1:Intravenous 200mg Rituximab, 1/week*2, if the proportion of CD19+ B lymphocytes in peripheral bloo ...	The Ophthalmology Department of the Chinese Peoples Liberation Army Hospital	NULL	Recruiting	18	70	Both	1:30;2:30;	Phase 4	China
5	JPRN-jRCTs051180080	12/12/2018	27/02/2019	Treatment of Neuromyelitis Optica with Mycophenolate Mofetil in Japanese Patients	Treatment of Neuromyelitis Optica with Mycophenolate Mofetilin Japanese Patients - An open treatment ...	Neuromyelitis optica	Mycophenolate mofetil treatment for 1 year	Sekiguchi Kenji	NULL	Complete	>= 20age old	< 80age old	Both	10	Phase 2	Japan
6	JPRN-UMIN000031135	2018/04/01	01/04/2018	Treatment of Neuromyelitis Optica with Mycophenolate Mofetil in Japanese Patients	Treatment of Neuromyelitis Optica with Mycophenolate Mofetilin Japanese Patients - An open treatment ...	Neuromyelitis Optica	Mycophenolate mofetil treatment for 1 year	Kobe University Hospital	NULL	Complete: follow-up continuing	20years-old	80years-old	Male and Female	10	Not selected	Japan
7	ChiCTR-OPB-16007730	2016-01-01	2016-01-09	Mycophenolate Mofetil Treatment of Neuromyelitis Optica in Chinese Patients (MONICA)	Mycophenolate Mofetil Treatment of Neuromyelitis Optica in Chinese Patients (MONICA)	Neuromyelitis optica	Case series:Mycophenolate Mofetil;	The third affiliated hospital,Sun Yat-sen university	NULL	Recruiting	18	65	Both	Case series:100;		China
8	NCT02809079 (ClinicalTrials.gov)	January 2016	12/6/2016	Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients	Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients	Neuromyelitis Optica Spectrum Disorders;Mycophenolate Mofetil;Efficacy and Safety	Drug: Mycophenolate mofetil;Drug: Prednisone	Third Affiliated Hospital, Sun Yat-Sen University	Zhongshan Ophthalmic Centre, Sun Yat-sen University;Nangfang Hospital, Southern Medical University	Enrolling by invitation	18 Years	65 Years	Both	100	Phase 4	NULL
9	ChiCTR-ICR-15007177	2014-08-30	2014-05-30	A Prospective Study on the Efficacy andSafety of Rituximab in Treatment for Neuromyelitis Optica ass ...	A Prospective Study on the Efficacy andSafety of Rituximab in Treatment for Neuromyelitis Optica ass ...	Neuromyelitis Optica associated Optic Neuritis	1:Intravenous 100mg Rituximab, 1/week*4 ;2:Oral azathioprine(2.5-3 mg/kg bodyweight/day) or mycophen ...	The Ophthalmology Department of the Chinese Peoples Liberation Army Hospital	NULL	Recruiting	18	70	Both	1:30;2:30;		China
10	NCT00618527 (ClinicalTrials.gov)	August 2006	6/2/2008	Combination Therapy Using Cellcept and Rebif in RRMS	Combination Therapy Using Mycophenolate Mofetil(CellCept) and Human Interferon beta1a (Rebif) in Ear ...	Multiple Sclerosis	Drug: mycophenolate mofetil (Cellcept);Drug: human interferon beta 1a (Rebif)	Aaron Boster	EMD Serono;Pfizer	Completed	18 Years	65 Years	Both	31	Phase 0	United States

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