13. 多発性硬化症／視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

144 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2021-005746-15-CZ (EUCTR)	14/09/2022	23/02/2022	A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients with Multi ...	A Multicenter, Single-arm, Open-label, Extension, Rollover Study To Evaluate The Long-term Safety An ...	Primary Progressive Multiple Sclerosis (PPMS)Relapsing Multiple Sclerosis (RMS) MedDRA version: 21.1 ...	Trade Name: Ocrevus Product Name: ocrelizumab 300mg/10ml Product Code: RO4964913/F07 INN or Proposed INN ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1300	Phase 3	United States;Serbia;Portugal;Belarus;Estonia;Slovakia;Greece;Spain;Ukraine;Russian Federation;Israe ...
2	EUCTR2021-005746-15-FI (EUCTR)	06/07/2022	04/04/2022	A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients with Multi ...	A Multicenter, Single-arm, Open-label, Extension, Rollover Study To Evaluate The Long-term Safety An ...	Primary Progressive Multiple Sclerosis (PPMS)Relapsing Multiple Sclerosis (RMS) MedDRA version: 21.1 ...	Trade Name: Ocrevus Product Name: ocrelizumab 300mg/10ml Product Code: RO4964913/F07 INN or Proposed INN ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1300	Phase 3	Portugal;Serbia;Belarus;United States;Estonia;Slovakia;Greece;Spain;Ukraine;Russian Federation;Israe ...
3	EUCTR2021-005746-15-NL (EUCTR)	04/07/2022	16/05/2022	A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients with Multi ...	A Multicenter, Single-arm, Open-label, Extension, Rollover Study To Evaluate The Long-term Safety An ...	Primary Progressive Multiple Sclerosis (PPMS)Relapsing Multiple Sclerosis (RMS) MedDRA version: 21.1 ...	Trade Name: Ocrevus Product Name: ocrelizumab 300mg/10ml Product Code: RO4964913/F07 INN or Proposed INN ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1300	Phase 3	Serbia;Portugal;Belarus;United States;Estonia;Slovakia;Greece;Spain;Ukraine;Russian Federation;Israe ...
4	EUCTR2021-003296-33-GR (EUCTR)	17/06/2022	28/12/2021	OPEN-LABEL MULTICENTER STUDY TO DETERMINE THE EFFECT OF OCRELIZUMAB ON LEPTOMENINGEAL INFLAMMATION I ...	OPEN-LABEL MULTICENTER STUDY TO DETERMINE THE EFFECT OF OCRELIZUMAB ON LEPTOMENINGEAL INFLAMMATION I ...	Active progressive multiple sclerosis MedDRA version: 20.0;Level: HLT;Classification code 10052785;T ...	Trade Name: OCREVUS Product Name: OCRELIZUMAB Product Code: RO4964913 INN or Proposed INN: Ocrelizumab O ...	F. Hoffmann-La Roche Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	50	Phase 4	Greece;Russian Federation
5	EUCTR2021-005746-15-ES (EUCTR)	09/05/2022	10/05/2022	A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients with Multi ...	A Multicenter, Single-arm, Open-label, Extension, Rollover Study To Evaluate The Long-term Safety An ...	Primary Progressive Multiple Sclerosis (PPMS)Relapsing Multiple Sclerosis (RMS) MedDRA version: 21.1 ...	Trade Name: Ocrevus Product Name: ocrelizumab 300mg/10ml Product Code: RO4964913/F07 INN or Proposed INN ...	Roche Farma S. A. U. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La R ...	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1300	Phase 3	Serbia;Portugal;Belarus;United States;Estonia;Slovakia;Greece;Spain;Ukraine;Russian Federation;Israe ...
6	EUCTR2020-005448-48-CZ (EUCTR)	15/03/2022	05/05/2021	A Study to Investigate the Pharmacokinetics, Pharmacodynamics, Safety and Radiological and Clinical ...	A PHASE III, NON-INFERIORITY, RANDOMIZED, OPEN-LABEL, PARALLEL GROUP, MULTICENTER STUDY TO INVESTIGA ...	Multiple Sclerosis (MS) MedDRA version: 21.1;Level: PT;Classification code 10063401;Term: Primary pr ...	Trade Name: Ocrevus Product Name: ocrelizumab Product Code: RO4964913 INN or Proposed INN: Ocrelizumab O ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	232	Phase 3	United States;Czechia;Spain;Ukraine;Turkey;Russian Federation;Italy;France;Czech Republic;Canada;Pol ...
7	EUCTR2019-003919-53-DE (EUCTR)	13/12/2021	11/02/2021	FENtrepid: A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared with Ocrelizumab in ...	A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, PARALLEL-GROUP STUDY TO EVALUATE TH ...	Primary Progressive multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063401;T ...	Product Name: fenebrutinib Product Code: RO7010939 INN or Proposed INN: FENEBRUTINIB Other descriptive ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	946	Phase 3	United States;Portugal;Greece;Spain;Ukraine;Russian Federation;Israel;Switzerland;France;Peru;Austra ...
8	EUCTR2019-003919-53-BG (EUCTR)	16/11/2021	16/07/2021	FENtrepid: A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared with Ocrelizumab in ...	A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, PARALLEL-GROUP STUDY TO EVALUATE TH ...	Primary Progressive multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063401;T ...	Product Name: fenebrutinib Product Code: RO7010939 INN or Proposed INN: FENEBRUTINIB Other descriptive ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	946	Phase 3	United States;Portugal;Greece;Spain;Ukraine;Israel;Russian Federation;Switzerland;France;Denmark;Aus ...
9	EUCTR2020-005448-48-PL (EUCTR)	13/09/2021	09/07/2021	A Study to Investigate the Pharmacokinetics, Pharmacodynamics, Safety and Radiological and Clinical ...	A PHASE III, NON-INFERIORITY, RANDOMIZED, OPEN-LABEL, PARALLEL GROUP, MULTICENTER STUDY TO INVESTIGA ...	Multiple Sclerosis (MS) MedDRA version: 21.1;Level: PT;Classification code 10063401;Term: Primary pr ...	Trade Name: Ocrevus Product Name: ocrelizumab Product Code: RO4964913 INN or Proposed INN: Ocrelizumab O ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	232	Phase 3	United States;Czechia;Spain;Ukraine;Turkey;Russian Federation;Italy;France;Czech Republic;Canada;Pol ...
10	EUCTR2019-003919-53-DK (EUCTR)	07/09/2021	01/03/2021	FENtrepid: A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared with Ocrelizumab in ...	A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, PARALLEL-GROUP STUDY TO EVALUATE TH ...	Primary Progressive multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063401;T ...	Product Name: fenebrutinib Product Code: RO7010939 INN or Proposed INN: FENEBRUTINIB Other descriptive ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	946	Phase 3	United States;Portugal;Greece;Spain;Ukraine;Israel;Russian Federation;Switzerland;France;Australia;D ...

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