13. 多発性硬化症／視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

17 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2017-003008-30-GB (EUCTR)	01/07/2020	17/05/2018	Simvastatin in Secondary Progressive Multiple Sclerosis	A double-blind, randomised, placebo-controlled single-site study of high dose simvastatintreatment f ...	Multiple Sclerosis (Secondary Progressive) MedDRA version: 20.0;Level: HLT;Classification code 10052 ...	Trade Name: Simvastatin 40 mg film-coated tablets Product Name: Simvastatin 40 mg film-coated tablets Pr ...	University College London	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	40	Phase 2	United Kingdom
2	EUCTR2019-003127-38-NL (EUCTR)	09/04/2020	09/04/2020	Research on the effect of add-on high dosage simvastatintreatment on progression in MS patients trea ...	Efficacy of add-on high dose simvastatinon markers for disease progression in MS patients treated wi ...	Multiple sclerosis;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Product Name: Simvastatin INN or Proposed INN: SIMVASTATIN Other descriptive name: Simvastatine	VUmc Neurology Department	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	100	Phase 2	Netherlands
3	NCT04178980 (ClinicalTrials.gov)	January 1, 2020	25/11/2019	Role of Simvastatin in Relapsing-Remitting Multiple Sclerosis	Double-blinded, Randomized Controlled Trial of SimvastatinUse As Adjuvant Therapy in Relapsing-Remit ...	Simvastatin Multiple Sclerosis	Drug: Simvastatin in relapsing remitting multiple sclerosis	Assiut University	NULL	Not yet recruiting	18 Years	65 Years	All	60	Phase 1	NULL
4	NCT03896217 (ClinicalTrials.gov)	May 16, 2019	26/10/2018	Simvastatin in Secondary Progressive Multiple Sclerosis	A Double-blind, Randomised, Placebo-controlled Single-site Study of High Dose SimvastatinTreatment f ...	Secondary Progressive Multiple Sclerosis	Drug: Simvastatin	University College, London	MS Society	Recruiting	18 Years	65 Years	All	40	Phase 2	United Kingdom
5	EUCTR2017-003328-56-GB (EUCTR)	19/12/2017	31/10/2017	MS-STAT2 - Multiple Sclerosis – Simvastatin Trial 2	A phase 3 randomised, double blind, clinical trial investigating the effectiveness of repurposed sim ...	Multiple sclerosis MedDRA version: 20.1;Level: PT;Classification code 10028245;Term: Multiple sclero ...	Trade Name: Simvastatin 40 mg film-coated tablets Product Name: Simvastatin 40 mg film-coated tablets IN ...	University College London Comprehensive Clinical Trials Unit	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1180	Phase 3	United Kingdom
6	EUCTR2006-001827-21-DK (EUCTR)	06/03/2009	15/01/2009	A Double Blind, Randomised, Placebo Controlled Study Investigating Simvastatinas an add-on Treatment ...	A Double Blind, Randomised, Placebo Controlled Study Investigating Simvastatinas an add-on Treatment ...	Multiple Sclerosis MedDRA version: 9.1;Level: LLT;Classification code 10028245;Term: Multiple sclero ...	Trade Name: Simvastatin Trade Name: Copaxone Product Name: Glatiramer acetate	Glostrup Hospital, Dep. of Neurology	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Denmark
7	NCT00429442 (ClinicalTrials.gov)	March 2008	30/1/2007	Simvastatin as an add-on Treatment to Copaxone for the Treatment of Relapsing Multiple Sclerosis	A Double Blind, Randomised, Placebo Controlled Study Investigating Simvastatinas an add-on Treatment ...	Relapsing Remitting Multiple Sclerosis	Drug: Simvastatin;Drug: placebo	Anna Tsakiri	Sanofi	Withdrawn	18 Years	60 Years	Both	0	Phase 3	Denmark
8	NCT00647348 (ClinicalTrials.gov)	January 2008	26/3/2008	Investigation of Simvastatin in Secondary Progressive Multiple Sclerosis	A Phase II Randomised, Placebo-controlled Clinical Trial of Simvastatinin Patients With Secondary Pr ...	Secondary Progressive Multiple Sclerosis	Drug: Simvastatin;Drug: Placebo	Imperial College London	NULL	Completed	18 Years	65 Years	All	140	Phase 2	United Kingdom
9	EUCTR2006-006347-31-GB (EUCTR)	06/09/2007	07/08/2007	A Phase II randomised placebo controlled clinical trial of Simvastatinin patients with secondary pro ...	A Phase II randomised placebo controlled clinical trial of Simvastatinin patients with secondary pro ...	Multiple Sclerosis MedDRA version: 9.1;Level: HLT;Classification code 10052785;Term: Multiple sclero ...	Product Name: Encapsulated Simvastatin tablets Product Code: MSTC-001 (MS-STAT)	Imperial College London	NULL	Not Recruiting			Female: yes Male: yes	140	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	United Kingdom
10	NCT00261326 (ClinicalTrials.gov)	September 2006	2/12/2005	Simvastatin Treatment of Patients With Acute Optic Neuritis	SimvastatinTreatment of Patients With Acut Optic Neuritis. A Doubleblind, Randomized and Placebo Con ...	Optic Neuritis;Multiple Sclerosis	Drug: simvastatin;Drug: placebo	Glostrup University Hospital, Copenhagen	Alpharma ApS	Active, not recruiting	18 Years	59 Years	Both	64	Phase 3	Denmark

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