13. 多発性硬化症/視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details
臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238
Showing 1 to 10 of 34 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05340985 (ClinicalTrials.gov) | July 2022 | 2/3/2022 | Investigating the Effects of Hydroxyvitamin D3 on Multiple Sclerosis | Investigating the Effects of Hydroxyvitamin D3 Versus Vitamin D3 on Clinical, and Radiologic Progress and Th17/Tregs Balance in MS Patients: A Randomized, Clinical Trial- a Pilot Study Investigating the Effects of Hydroxyvitamin D3 Versus Vitamin D3 on Clinical, and Radiologic Progres ... | Multiple Sclerosis, Relapsing-Remitting;Adult ALL;Vitamin D3 Deficiency | Dietary Supplement: 25(OH)D3;Dietary Supplement: vitamin D3 | Tehran University of Medical Sciences | Boston University | Not yet recruiting | 18 Years | 55 Years | All | 54 | Phase 4 | NULL |
2 | NCT03610139 (ClinicalTrials.gov) | May 21, 2018 | 13/7/2018 | Longitudinal Effect of Vitamin D3 Replacement on Cognitive Performance and MRI Markers in Multiple Sclerosis Patients Longitudinal Effect of Vitamin D3 Replacement on Cognitive Performance and MRI Markers in Multiple S ... | Longitudinal Effect of Vitamin D3 Replacement on Cognitive Performance and MRI Markers in Multiple Sclerosis Patients: A Single-Blind Randomized Clinical Trial Longitudinal Effect of Vitamin D3 Replacement on Cognitive Performance and MRI Markers in Multiple S ... | Multiple Sclerosis;Multiple Sclerosis, Relapsing-Remitting;Clinically Isolated Syndrome;Clinically Isolated Syndrome, CNS Demyelinating;Vitamin D3 Deficiency Multiple Sclerosis;Multiple Sclerosis, Relapsing-Remitting;Clinically Isolated Syndrome;Clinically I ... | Dietary Supplement: Vitamin D3 | American University of Beirut Medical Center | NULL | Recruiting | 18 Years | N/A | All | 162 | N/A | Lebanon |
3 | NCT03385356 (ClinicalTrials.gov) | December 19, 2017 | 20/12/2017 | Impact of Vitamin D Supplementation in Patients With Multiple Sclerosis | Impact of Vitamin D Supplementation in Patients With Multiple Sclerosis | Multiple Sclerosis, Relapsing-Remitting;Vitamin D Deficiency | Drug: Vitamin D | University Medical Centre Maribor | Medical Faculty Maribor | Completed | 18 Years | 60 Years | All | 89 | Phase 4 | Slovenia |
4 | EUCTR2017-004846-31-SI (EUCTR) | 14/12/2017 | 05/12/2017 | Vitamin D supplementation in patients with multiple sclerosis | Impact of vitamin D supplementation in patients with multiple sclerosis | Relapsing remitting multiple sclerosis MedDRA version: 20.1;Level: LLT;Classification code 10064137;Term: Progression of multiple sclerosis;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Relapsing remitting multiple sclerosis MedDRA version: 20.1;Level: LLT;Classification code 10064137; ... | Trade Name: Oleovit D3 14.400 IU/ml oral drops, solution | University medical centre Maribor | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 95 | Phase 4 | Slovenia | ||
5 | NCT02696590 (ClinicalTrials.gov) | July 2015 | 18/2/2016 | High Dose Oral Versus Intramuscular Vitamin D3 Supplementation In Multiple Sclerosis Patients | Isfahan University of Medical Sciences | Relapsing Remitting Multiple Sclerosis | Dietary Supplement: Vitamin D3 | Isfahan University of Medical Sciences | NULL | Completed | 23 Years | 59 Years | Both | 200 | N/A | Iran, Islamic Republic of |
6 | NCT02096133 (ClinicalTrials.gov) | October 13, 2014 | 21/3/2014 | Vitamin D3 and the Stress-axis in MS | Regulation of the Stress-axis by Vitamin D3 in Subjects With Multiple Sclerosis; a Double-blinded, Randomized, Placebo-controlled Study Regulation of the Stress-axis by Vitamin D3 in Subjects With Multiple Sclerosis; a Double-blinded, R ... | Multiple Sclerosis | Drug: Cholecalciferol;Other: Placebo comparator | Academic MS Center Limburg | NULL | Terminated | 18 Years | N/A | Female | 54 | Phase 2 | Netherlands |
7 | NCT01817166 (ClinicalTrials.gov) | July 16, 2013 | 20/3/2013 | Efficacy of Cholecalciferol (Vitamin D3) for Delaying the Diagnosis of MS After a Clinically Isolated Syndrome Efficacy of Cholecalciferol (Vitamin D3) for Delaying the Diagnosis of MS After a Clinically Isolate ... | Multicentric, Randomized, Double-blind Versus Placebo Study Evaluating the Efficacy of Treatment With Cholecalciferol (Vitamin D3) for Delaying the Diagnosis of Multiple Sclerosis (MS) After a Clinically Isolated Syndrome (CIS). Comparison of Conversion Rates After 2 Years. Multicentric, Randomized, Double-blind Versus Placebo Study Evaluating the Efficacy of Treatment Wit ... | Multiple Sclerosis | Drug: Vitamin D;Drug: Placebo;Other: Imaging;Biological: Lumbar puncture;Biological: Blood sampling;Biological: Urine samples Drug: Vitamin D;Drug: Placebo;Other: Imaging;Biological: Lumbar puncture;Biological: Blood sampling; ... | Centre Hospitalier Universitaire de Nimes | NULL | Active, not recruiting | 18 Years | 56 Years | All | 316 | Phase 3 | France |
8 | NCT01768039 (ClinicalTrials.gov) | March 2013 | 11/1/2013 | Vitamine D in Multiple Sclerosis | Randomised Double Blind Placebo-controlled Trial of Vitamine D Supplement in Multiple Sclerosis | Multiple Sclerosis | Drug: Vitamin D;Drug: Placebo | Mazandaran University of Medical Sciences | NULL | Not yet recruiting | 18 Years | 50 Years | Both | 240 | Phase 3 | Iran, Islamic Republic of |
9 | NCT01753375 (ClinicalTrials.gov) | January 2013 | 17/12/2012 | Role of Vitamin D in Reducing the Relapse Rate in Patients With Multiple Sclerosis | Role of Vitamin D on the Relapse Rate of Multiple Sclerosis | Multiple Sclerosis | Dietary Supplement: Vitamin D3;Dietary Supplement: Placebo | AlJohara M AlQuaiz, M.D. | NULL | Not yet recruiting | 18 Years | 55 Years | Both | 200 | Phase 2 | Saudi Arabia |
10 | NCT01728922 (ClinicalTrials.gov) | November 6, 2012 | 8/11/2012 | Dose-related Effects of Vitamin D3 on Immune Responses in Patients With Clinically Isolated Syndrome Dose-related Effects of Vitamin D3 on Immune Responses in Patients With Clinically Isolated Syndrome ... | Dose-related Effects of Vitamin D3 on Immune Responses in Patients With Clinically Isolated Syndrome and Healthy Control Participants. An Exploratory Double Blind Placebo Randomised Controlled Study. Dose-related Effects of Vitamin D3 on Immune Responses in Patients With Clinically Isolated Syndrome ... | Clinically Isolated Syndrome;Multiple Sclerosis | Dietary Supplement: 5000IU vitamin D;Dietary Supplement: 10000IU vitamin D;Other: Placebo | University College Dublin | University of Dublin, Trinity College;St Vincent's University Hospital, Ireland | Completed | 18 Years | 55 Years | All | 64 | Phase 1/Phase 2 | Ireland |