14. 慢性炎症性脱髄性多発神経炎／多巣性運動ニューロパチー Chronic inflammatory demyelinating polyneuropathy Clinical trials / Disease details
臨床試験数 : 175 / 薬物数 : 161 - (DrugBank : 41) / 標的遺伝子数 : 13 - 標的パスウェイ数 : 24
Showing 1 to 10 of 175 diseases
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04480450 (ClinicalTrials.gov) | July 2023 | 16/7/2020 | Rituximab in Chronic Inflammatory Demyelinating Polyneuropathy | Rituximab in Chronic Inflammatory Demyelinating Polyneuropathy: A Phase II Study | Chronic Inflammatory Demyelinating Polyneuropathy | Drug: Rituximab | University of Kansas Medical Center | NULL | Not yet recruiting | 18 Years | N/A | All | 40 | Phase 2 | NULL |
| 2 | NCT05405361 (ClinicalTrials.gov) | January 18, 2023 | 17/5/2022 | A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, P ... | A Long-term Extension of the ARGX-117-2002 Trial to Evaluate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy A Long-term Extension of the ARGX-117-2002 Trial to Evaluate the Long-term Safety and Tolerability, ... | Multifocal Motor Neuropathy (MMN) | Biological: ARGX-117;Other: Placebo | argenx | NULL | Recruiting | 18 Years | N/A | All | 48 | Phase 2 | United States |
| 3 | NCT04881682 (ClinicalTrials.gov) | January 1, 2023 | 28/4/2021 | Immunoadsorption Versus Immunoglobulins for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Immunoadsorption Versus Immunoglobulins for Treatment of Chronic Inflammatory Demyelinating Polyneur ... | Immunoadsorption Versus Immunoglobulins for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Immunoadsorption Versus Immunoglobulins for Treatment of Chronic Inflammatory Demyelinating Polyneur ... | CIDP | Device: Immunoadsorption;Biological: Immunoglobulins | University of Ulm | Miltenyi Biomedicine GmbH | Not yet recruiting | 18 Years | N/A | All | 20 | Phase 2 | Germany |
| 4 | NCT04929236 (ClinicalTrials.gov) | January 1, 2023 | 11/6/2021 | Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflam ... | Multicenter, Prospective, Double-Blinded, Parallel Group, Randomized Phase III Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients Multicenter, Prospective, Double-Blinded, Parallel Group, Randomized Phase III Study to Evaluate Saf ... | Pediatric Chronic Inflammatory Demyelinating Polyneuropathy | Drug: Panzyga | Octapharma | NULL | Not yet recruiting | 2 Years | 17 Years | All | 30 | Phase 3 | NULL |
| 5 | NCT05581199 (ClinicalTrials.gov) | December 15, 2022 | 12/10/2022 | To Assess Efficacy and Safety of Batoclimab in Adult Participants With Active CIDP | A Phase 2b, Multi-center, Randomized, Quadruple-blind, Placebo-controlled Study of Batoclimab Treatment in Adult Participants With Active Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) A Phase 2b, Multi-center, Randomized, Quadruple-blind, Placebo-controlled Study of Batoclimab Treatm ... | Chronic Inflammatory Demyelinating Polyneuropathy | Drug: Batoclimab 680 milligrams (mg) subcutaneous (SC) weekly;Drug: Batoclimab 340 mg SC weekly;Drug: Placebo Drug: Batoclimab680 milligrams (mg) subcutaneous (SC) weekly;Drug: Batoclimab340 mg SC weekly;Drug: ... | Immunovant Sciences GmbH | NULL | Recruiting | 18 Years | N/A | All | 240 | Phase 2 | United States |
| 6 | EUCTR2021-004998-32-NL (EUCTR) | 05/12/2022 | 19/09/2022 | A clinical trial to investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy A clinical trial to investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, P ... | A Long-Term Extension of the ARGX-117-2002 Trial to Evaluate the Long-term Safety and Tolerabillity, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults with Multifocal Motor Neuropathy - ARDA+ A Long-Term Extension of the ARGX-117-2002 Trial to Evaluate the Long-term Safety and Tolerabillity, ... | Multifocal Motor Neuropathy MedDRA version: 21.1;Level: PT;Classification code 10065579;Term: Multifocal motor neuropathy;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Multifocal Motor Neuropathy MedDRA version: 21.1;Level: PT;Classification code 10065579;Term: Multif ... | Product Name: ARGX-117 IV Product Code: ARGX-117 IV INN or Proposed INN: not defined Other descriptive name: ARGX-117 Product Name: ARGX-117 IV Product Code: ARGX-117 IV INN or Proposed INN: not defined Other descriptive name: ARGX-117 Product Name: ARGX-117IV Product Code: ARGX-117IV INN or Proposed INN: not defined Other descriptive na ... | argenx BV | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 48 | Phase 2 | United Kingdom;Italy;France;United States;Canada;Belgium;Spain;Poland;Austria;Germany;Netherlands | ||
| 7 | NCT05584631 (ClinicalTrials.gov) | October 18, 2022 | 10/10/2022 | IVIG vs SCIG in CIDP | The Influence of Body Composition on Immunoglobulin Disposition After Intravenous and Subcutaneous Administration The Influence of Body Composition on Immunoglobulin Disposition After Intravenous and Subcutaneous A ... | CIDP;Immunoglobulin Deficiency;Chronic Inflammatory Demyelinating Polyneuropathy | Drug: Intravenous immune globulin G;Drug: Subcutaneous immune globulin G | Rutgers, The State University of New Jersey | NULL | Recruiting | 18 Years | 65 Years | All | 20 | Phase 1 | United States |
| 8 | NCT05327114 (ClinicalTrials.gov) | September 23, 2022 | 7/4/2022 | Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneur ... | Phase 2/3, Multistage, Multicenter, Randomized, Double-Blind, Placebo-Controlled Parallel Group Withdrawal Study to Evaluate the Efficacy and Safety of Nipocalimab Administered to Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Phase 2/3, Multistage, Multicenter, Randomized, Double-Blind, Placebo-Controlled Parallel Group With ... | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | Drug: Nipocalimab;Drug: Placebo | Janssen Research & Development, LLC | NULL | Recruiting | 18 Years | N/A | All | 300 | Phase 2/Phase 3 | United States;Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Poland;Portugal;Slovakia;Spain;Taiwan;United Kingdom;Romania;South Africa United States;Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Czechia;Denm ... |
| 9 | JPRN-jRCT2041220037 | 10/09/2022 | 23/06/2022 | Efficacy and Safety Study of Nipocalimab for Adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Efficacy and Safety Study of Nipocalimab for Adults with Chronic Inflammatory Demyelinating Polyneur ... | Phase 2/3, Multistage, Multicenter, Randomized, Double-Blind, Placebo-Controlled Parallel Group Withdrawal Study to Evaluate the Efficacy and Safety of Nipocalimab Administered to Adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Phase 2/3, Multistage, Multicenter, Randomized, Double-Blind, Placebo-Controlled Parallel Group With ... | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | Nipocalimab : Nipocalimab will be administered intravenously. Participants in Stage A (Open-label) will receive a loading dose of nipocalimab (Dose 1) intravenous (IV) infusion on Day 1, followed by nipocalimab (Dose 2) IV infusion once every 2 weeks (q2w) from Week 2 to Week 12. Participants who demonstrate evidence of clinical improvement in Stage A (responders) will enter Stage B (Double-blind) and receive nipocalimab (Dose 2) IV infusion q2w starting on Day 1 up to Week 52. After completion of Stage B or discontinuation from Stage B due to relapse, participants will have the option to enter the open label extension (OLE) phase and receive nipocalimab (Dose 2) IV infusion q2w starting on OLE Day 1 until 2 years after marketing authorization in a participant s local country or until nipocalimab becomes available commercially or via other continued access program, whichever comes first. Placebo : Placebo will be administered intravenously. Participants receiving nipocalimab in Stage A and who demonstrate evidence of clinical improvement in Stage A (responders) will enter Stage B (Double-blind) and receive placebo IV infusion q2w starting on Day 1 up to Week 52. After completion of Stage B or discontinuation from Stage B due to relapse, participants will have the option to enter the open label extension (OLE) phase and receive nipocalimab (Dose 2) IV infusion q2w starting on OLE Day 1 until 2 years after marketing authorization in a participant s local country or until nipocalimab becomes available commercially or via other continued access program, whichever comes first. Nipocalimab: Nipocalimabwill be administered intravenously. Participants in Stage A (Open-label) will ... | Nakano Masayoshi | NULL | Pending | >= 18age old | Not applicable | Both | 300 | Phase 2-3 | Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Colombia;Czechia;Germany;Denmark;Spain;France;UnitedKingdomOf GreatBritainAndNorthernIreland;Greece;Italy;Korea,RepublicOf;Mexico;Poland;Portugal;Slovakia;Taiwan,ProvinceOf China;UnitedStates OfAmerica;Japan Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Colombia;Czechia;Germany;Denmark;Spain;Franc ... |
| 10 | NCT04672733 (ClinicalTrials.gov) | June 10, 2022 | 11/12/2020 | Hizentra® in Inflammatory Neuropathies - pHeNIx Study | Hizentra® in Inflammatory Neuropathies - pHeNIx Study | Chronic Inflammatory Demyelinating Polyneuropathy | Biological: Hizentra | CSL Behring | NULL | Recruiting | 18 Years | N/A | All | 100 | France |