162. 類天疱瘡（後天性表皮水疱症を含む。） Pemphigoid Clinical trials / Disease details

臨床試験数 : 90 / 薬物数 : 122 - (DrugBank : 47) / 標的遺伝子数 : 34 - 標的パスウェイ数 : 144

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04128176 (ClinicalTrials.gov)	May 25, 2023	12/10/2019	Efficacy and Safety of Rituximab Combined With Omalizumab in Patients With Bullous Pemphigoid	An Open-Label Study to Evaluate the Efficacy and Safety of Rituximab Combined With Omalizumab in Pat ...	Bullous Pemphigoid	Drug: Rituximab combined with Omalizumab	University of California, Davis	NULL	Not yet recruiting	18 Years	90 Years	All	15	Phase 3	United States
2	NCT05520086 (ClinicalTrials.gov)	November 11, 2022	22/8/2022	Clinical Trial to Evaluate Safety and Efficacy of Cell Therapy in Patients With Cicatricial Conjunti ...	Phase IIa Multicenter Clinical Trial to Determine the Feasibility and Safety of the Use of Adipose-d ...	Chronic Conjunctivitis;Stevens-Johnson Syndrome;Lyell Syndrome;Pemphigoid	Drug: Single Dose;Drug: Double Dose	Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz	Effice Servicios Para la Investigacion S.L.	Recruiting	18 Years	N/A	All	20	Phase 1/Phase 2	Spain
3	NCT05594472 (ClinicalTrials.gov)	November 1, 2022	21/10/2022	Ozonated Olive Oil in Treatment of Pemphigus Vulgaris and Bullous Pemphigoid	Ozonated Olive Oil in Treatment of Pemphigus Vulgaris and Bullous PemphigoidCompared to Conventional ...	Pemphigus Vulgaris;Bullous Pemphigoid	Drug: Ozonated olive oil;Drug: Topical garamycin cream	Cairo University	NULL	Recruiting	18 Years	N/A	All	30	Phase 3	Egypt
4	NCT05649579 (ClinicalTrials.gov)	September 1, 2022	6/12/2022	Efficacy and Safety of Dupilumab in Patients With Bullous Pemphigoid	Efficacy and Safety of Dupilumab in Patients With Bullous Pemphigoid: a Multicenter Retrosepctive St ...	Bullous Pemphigoid	Drug: Dupilumab	Peking University First Hospital	Ruijin Hospital;Cancer Institute and Hospital, Chinese Academy of Medical Sciences;West China Hospit ...	Recruiting	18 Years	N/A	All	146		China
5	EUCTR2021-005486-40-ES (EUCTR)	22/07/2022	11/02/2022	Clinical Trial to evaluate safety and efficacy of cell therapy in patients with cicatricial conjunti ...	Phase IIa multicenter clinical trial to determine the feasibility and safety of the use of adipose-d ...	Cicatricial conjunctivitis associated with Lyell's syndrome, Stevens-Johnson syndrome and mucous mem ...	Product Name: allogenic mesenchymal stem cell isolated from adipose tissue INN or Proposed INN: ALLOG ...	FUNDACION JIMENEZ DIAZ HEALTH RESEARCH INSTITUTE	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	20	Phase 2	Spain
6	NCT05267600 (ClinicalTrials.gov)	June 9, 2022	14/2/2022	A Phase 2/3 Study of Efgartigimod PH20 SC in Adult Participants With Bullous Pemphigoid (BALLAD)	A Phase 2/3, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group Study to Investigate the ...	Bullous Pemphigoid	Biological: efgartigimod PH20 SC;Other: placebo;Drug: Prednisone	argenx	NULL	Recruiting	18 Years	N/A	All	160	Phase 2/Phase 3	United States;Australia;Bulgaria;Croatia;France;Germany;Greece;Hungary;Israel;Italy;Latvia;Netherlan ...
7	EUCTR2021-003087-27-BG (EUCTR)	19/05/2022	07/03/2022	A study to assess the efficacy and safety of a subcutaneous formulation of efgartigimod PH20 in adul ...	A Phase 2/3, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group Study to Investigate the ...	Bullous Pemphigoid MedDRA version: 21.1;Level: LLT;Classification code 10006567;Term: Bullous pemphi ...	Product Name: Efgartigimod PH20 SC INN or Proposed INN: EFGARTIGIMOD ALFA	argenx BV	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	160	Phase 2;Phase 3	Serbia;United States;Czechia;Slovakia;Greece;Spain;Ukraine;Russian Federation;Israel;United Kingdom; ...
8	NCT05061771 (ClinicalTrials.gov)	May 6, 2022	15/9/2021	Nomacopan Therapy in Adult Patients With Bullous PemphigoidReceiving Adjunct Oral Corticosteroid The ...	A Randomized, Part A Partial Blinded and Part B Double Blinded, Placebo-controlled 24-week Clinical ...	Bullous Pemphigoid	Drug: nomacopan (rVA576);Other: Placebo	AKARI Therapeutics	NULL	Withdrawn	18 Years	99 Years	All	0	Phase 3	United States;Germany;Netherlands;Poland
9	EUCTR2021-003087-27-HR (EUCTR)	29/04/2022	16/05/2022	A study to assess the efficacy and safety of a subcutaneous formulation of efgartigimod PH20 in adul ...	A Phase 2/3, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group Study to Investigate the ...	Bullous Pemphigoid MedDRA version: 21.1;Level: LLT;Classification code 10006567;Term: Bullous pemphi ...	Product Name: Efgartigimod PH20 SC INN or Proposed INN: EFGARTIGIMOD ALFA	argenx BV	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	160	Phase 2;Phase 3	Germany;China;Japan;Australia;Bulgaria;Serbia;United States;Greece;Spain;Ukraine;Russian Federation; ...
10	ChiCTR2200058412	2022-04-28	2022-04-09	A clinical study to evaluate the effectiveness and safety of Dupilumab injection (Dupixent ?R) in th ...	A clinical study to evaluate the effectiveness and safety of Dupilumab injection (Dupixent ?R) in th ...	Bullous Pemphigoid, BP	Experimental group:Dupilumab;	Xijing Hospital	NULL	Pending			Both	Experimental group:8;		China

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