167. マルファン症候群 Marfan syndrome Clinical trials / Disease details

臨床試験数 : 21 / 薬物数 : 40 - (DrugBank : 11) / 標的遺伝子数 : 10 - 標的パスウェイ数 : 50

10 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01715207 (ClinicalTrials.gov)	June 2010	24/10/2012	Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFS	Comparison Study of the Effect of Aliskiren Versus Negative Controls on Aortic Stiffness in Patients ...	Marfan Syndrome	Drug: Aliskiren;Drug: Atenolol	Samsung Medical Center	NULL	Completed	14 Years	55 Years	All	30	Phase 3	Korea, Republic of
2	NCT01145612 (ClinicalTrials.gov)	October 2008	15/6/2010	Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome	A Clinical Trial to Assess the Efficacy and Safety of Losartan Versus Atenololin the Prevention of P ...	Marfan Syndrome	Drug: Losartan;Drug: Atenolol	Forteza, Albert, M.D.	Ministry of Health, Spain	Active, not recruiting	5 Years	60 Years	Both	140	Phase 3	Spain
3	EUCTR2007-001125-97-ES (EUCTR)	20/05/2008	03/12/2007	Eficacia y Seguridad de Losartán vs Atenololen la prevención de la dilatación progresiva de la aorta ...	Eficacia y Seguridad de Losartán vs Atenololen la prevención de la dilatación progresiva de la aorta ...	The aortic dilatation in Marfan syndrome with two different treatments: losartan vs atenolol MedDRA ...	Trade Name: cozaar 50 INN or Proposed INN: LOSARTAN POTASSIUM Trade Name: blokium 50 INN or Proposed INN ...	alberto forteza	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Spain
4	NCT00593710 (ClinicalTrials.gov)	January 2008	3/1/2008	Losartan Versus Atenolol for the Treatment of Marfan Syndrome	A Randomized Double-blind Study Assessing the Effects of Losartan Versus Atenololon Pulse Wave Veloc ...	Marfan Syndrome	Drug: Losartan;Drug: Atenolol	University of British Columbia	Heart and Stroke Foundation of Canada	Completed	12 Years	25 Years	Both	17	Phase 2	Canada
5	NCT00723801 (ClinicalTrials.gov)	October 2007	25/7/2008	Effects of Losartan Versus Atenololon Aortic and Cardiac Muscle Stiffness in Adults With Marfan Synd ...	Effects of Losartan vs Atenololon Aortic Stiffness and Diastolic Function in Adults With Marfan Synd ...	Marfan Syndrome	Drug: Atenolol;Drug: Losartan	Brigham and Women's Hospital	Boston Children’s Hospital	Completed	25 Years	N/A	All	40	Phase 3	United States
6	NCT00651235 (ClinicalTrials.gov)	February 2007	3/3/2008	A Randomized, Open-label, LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients Wi ...	A Randomized, Open-label, Active Control Trial to Evaluate the Effect of LOSARTAN Therapy on the Pro ...	Marfan Syndrome	Drug: Losartan and Atenolol or Propranolol;Drug: Atenolol or Propranolol	National Taiwan University Hospital	NULL	Recruiting	1 Year	N/A	Both	44	Phase 2	Taiwan
7	NCT00429364 (ClinicalTrials.gov)	January 2007	29/1/2007	Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Sy ...	Trial of Beta Blocker Therapy (Atenolol) Versus Angiotensin II Receptor Blocker Therapy (Losartan) i ...	Marfan Syndrome	Drug: Losartan Potassium;Drug: Atenolol	New England Research Institutes	National Heart, Lung, and Blood Institute (NHLBI);FDA Office of Orphan Products Development;National ...	Completed	6 Months	25 Years	All	608	Phase 3	United States;Belgium;Canada
8	EUCTR2006-003991-37-BE (EUCTR)	13/12/2006	06/12/2006	Trial of beta blocker therapy (atenolol) vs. angiotensin II receptor blocker therapy (losartan) in i ...	Trial of beta blocker therapy (atenolol) vs. angiotensin II receptor blocker therapy (losartan) in i ...	Marfan syndrome MedDRA version: 8.1;Level: LLT;Classification code 10026829;Term: Marfan's syndrome	Product Name: losartan INN or Proposed INN: Losartan potassium Product Name: losartan INN or Proposed IN ...	University Hospital Gent	NULL	Not Recruiting			Female: yes Male: yes	600		Belgium
9	NCT01295047 (ClinicalTrials.gov)	July 2006	11/2/2011	Comparison of Medical Therapies in Marfan Syndrome.	Effects of Atenolol, Perindopril and Verapamil on Haemodynamic and Vascular Function in Marfan Syndr ...	Marfan Syndrome	Drug: Atenolol;Drug: VERAPAMIL;Drug: Perindopril	Cardiff University	NULL	Completed	16 Years	60 Years	Both	18	Phase 4	United Kingdom
10	EUCTR2005-000749-13-GB (EUCTR)	30/07/2005	20/06/2005	A Randomised Double-Blind Trial of Medical Treatment In Marfan Syndrome.	A Randomised Double-Blind Trial of Medical Treatment In Marfan Syndrome.	Marfan Syndrome	Trade Name: Atenolol Product Name: Atenolol Product Code: N/A INN or Proposed INN: N/A Other descriptive ...	Cardiff University	NULL	Not Recruiting			Female: yes Male: yes	60	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United Kingdom

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