167. マルファン症候群 Marfan syndrome Clinical trials / Disease details

臨床試験数 : 21 / 薬物数 : 40 - (DrugBank : 11) / 標的遺伝子数 : 10 - 標的パスウェイ数 : 50

2 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01949233 (ClinicalTrials.gov)	October 2013	6/8/2013	The Oxford Marfan Trial	A Randomised, Double-blind, Placebo-controlled Pilot Trial of Irbesartan, Doxycycline and a Combination on Markers of Vascular Dysfunction in the Marfan Syndrome, Using Cardiovascular Magnetic Resonance Imaging	Marfan Syndrome	Drug: Irbesartan 150-300mg capsules daily for 6 months;Drug: Doxycycline 100-200mg capsules daily for 6 months;Drug: Doxycycline placebo capsules daily for 6 months;Drug: Irbesartan placebo capsules daily for 6 months	University of Oxford	Oxford University Hospitals NHS Trust	Recruiting	13 Years	N/A	Both	56	Phase 2	United Kingdom
2	EUCTR2010-023612-14-GB (EUCTR)	08/03/2013	20/12/2012	The Oxford Marfan Trial	A randomised, double-blind, placebo-controlled pilot trial of irbesartan, doxycycline and a combination on markers of vascular dysfunction in the Marfan syndrome, using cardiovascular magnetic resonance imaging - The Oxford Marfan Trial Version 1.0	Marfan syndrome. MedDRA version: 14.1;Level: PT;Classification code 10026829;Term: Marfan's syndrome;System Organ Class: 10010331 - Congenital, familial and genetic disorders ;Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]	Trade Name: Aprovel Product Name: Aprovel INN or Proposed INN: Irbesartan Trade Name: Vibrox 100mg Capsules Product Name: Vibrox INN or Proposed INN: Doxycycline Hyclate Ph.Eur	Clinical Trials and Research Governance	NULL	Not Recruiting			Female: yes Male: yes	56	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): no	United Kingdom