2. 筋萎縮性側索硬化症 Amyotrophic lateral sclerosis Clinical trials / Disease details
臨床試験数 : 645 / 薬物数 : 589 - (DrugBank : 163) / 標的遺伝子数 : 150 - 標的パスウェイ数 : 225
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2008-002062-62-NL (EUCTR) | 14/10/2008 | 02/06/2008 | A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) | A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) | Amyotrophic lateral sclerosis (ALS). MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier | Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel | Teva Pharmaceutical Industries, Ltd | NULL | Not Recruiting | Female: yes Male: yes | 540 | Hungary;Germany;Netherlands;Belgium;France;Spain;Italy | |||
| 2 | EUCTR2008-002062-62-FR (EUCTR) | 22/09/2008 | 19/06/2008 | A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) | A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) | Amyotrophic lateral sclerosis (ALS). MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier | Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel | Teva Pharmaceutical Industries, Ltd | NULL | Not Recruiting | Female: yes Male: yes | 540 | Phase 2 | France;Hungary;Belgium;Spain;Germany;Netherlands;Italy | ||
| 3 | EUCTR2008-002062-62-HU (EUCTR) | 17/09/2008 | 17/12/2008 | A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). | A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). | Amyotrophic lateral sclerosis (ALS). MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier | Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel | Teva Pharmaceutical Industries, Ltd | NULL | Not Recruiting | Female: yes Male: yes | 540 | Hungary;Germany;Netherlands;Belgium;France;Spain;Italy | |||
| 4 | EUCTR2008-002062-62-DE (EUCTR) | 08/09/2008 | 19/01/2009 | A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). - ALSTAR | A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). - ALSTAR | Amyotrophic lateral sclerosis (ALS). MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier | Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel | Teva Pharmaceutical Industries, Ltd | NULL | Not Recruiting | Female: yes Male: yes | 540 | Hungary;Germany;Netherlands;Belgium;France;Spain;Italy | |||
| 5 | EUCTR2008-002062-62-ES (EUCTR) | 13/08/2008 | 26/06/2008 | Estudio multinacional, multicéntrico, randomizado, doble ciego, controlado con placebo y de grupos paralelos para evaluar la eficacia, tolerabilidad y seguridad de Talampanel en pacientes con Esclerosis Lateral Amiotrófica (ELA)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) | Estudio multinacional, multicéntrico, randomizado, doble ciego, controlado con placebo y de grupos paralelos para evaluar la eficacia, tolerabilidad y seguridad de Talampanel en pacientes con Esclerosis Lateral Amiotrófica (ELA)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) | Esclerosis Lateral Amiotrófica (ELA).Amyotrophic lateral sclerosis (ALS). MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier | Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel | Teva Pharmaceutical Industries, Ltd | NULL | Not Recruiting | Female: yes Male: yes | 540 | Phase 2 | France;Hungary;Belgium;Spain;Germany;Netherlands;Italy | ||
| 6 | EUCTR2008-002062-62-BE (EUCTR) | 31/07/2008 | 11/07/2008 | A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). | A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). | Amyotrophic lateral sclerosis (ALS). MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier | Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel Product Name: talampanel Product Code: TV-7110 INN or Proposed INN: Not available yet Other descriptive name: talampanel | Teva Pharmaceutical Industries, Ltd | NULL | Not Recruiting | Female: yes Male: yes | 540 | Hungary;Germany;Netherlands;Belgium;France;Spain;Italy | |||
| 7 | EUCTR2008-002062-62-IT (EUCTR) | 16/06/2008 | 27/06/2008 | A Multinational, Multicenter, Randomized, Double-Blind, Placebo- Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) - ALSTAR | A Multinational, Multicenter, Randomized, Double-Blind, Placebo- Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) - ALSTAR | Amyotrophic Lateral Sclerosis MedDRA version: 9.1;Level: LLT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier | Product Name: tallampanel Product Code: TV-7110 Product Name: talampanel | Teva Pharmaceutical Industries,Ltd | NULL | Not Recruiting | Female: yes Male: yes | 540 | Hungary;Germany;Netherlands;Belgium;France;Spain;Italy |