205. 脆弱X症候群関連疾患 Fragile X syndrome related disease Clinical trials / Disease details


臨床試験数 : 5 薬物数 : 7 - (DrugBank : 5) / 標的遺伝子数 : 22 - 標的パスウェイ数 : 25

  
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PhaseCountries
1NCT05233579
(ClinicalTrials.gov)
June 25, 202120/10/2021Open-Label Trial of Sulforaphane in Premutation Carriers With FXTASOpen-Label Trial of Sulforaphane in Premutation Carriers With FXTAS to Find BiomarkersFragile X Associated Tremor/Ataxia Syndrome (Fxtas) (Diagnosis)Dietary Supplement: SulforaphaneUniversity of California, DavisNULLRecruiting50 Years85 YearsAll15N/AUnited States
2NCT02603926
(ClinicalTrials.gov)
October 20155/11/2015Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With AllopregnanoloneTreatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With AllopregnanoloneFragile X-associated Tremor/Ataxia SyndromeDrug: AllopregnanoloneRandi J. Hagerman, MDNULLCompleted50 Years85 YearsAll6Phase 2United States
3NCT02197104
(ClinicalTrials.gov)
January 201514/7/2014Citocoline for Treatment in Fragile X-associated Tremor/Ataxia SyndromePhase 2 Study of Citocoline for Treatment in Fragile X-associated Tremor/Ataxia SyndromeFragile X Tremor/Ataxia SyndromeDrug: citocolineRush University Medical CenterNULLCompleted18 Years90 YearsAll10Phase 2United States
4NCT00584948
(ClinicalTrials.gov)
September 200722/12/2007Memantine Treatment in Fragile X-Associated Tremor/Ataxia SyndromeCharacterization and Treatment of CNS Abnormalities in Premutation Carriers: A Double-Blind Placebo-Controlled Trial of MemantineFragile X-Associated Tremor/Ataxia Syndrome;Fragile X Premutation CarriersDrug: Memantine;Drug: PlaceboUniversity of California, DavisNational Institute on Aging (NIA);Forest LaboratoriesCompleted30 Years80 YearsAll94N/AUnited States
5NCT00033293
(ClinicalTrials.gov)
March 15, 20049/4/2002Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With NeuroblastomaA Pilot Study Randomized Trial of Intravenous Gammaglobulin Therapy for Patients With Neuroblastoma Associated Opsoclonus-Myoclonus-Ataxia Syndrome Treated With Chemotherapy and PrednisoneDisseminated Neuroblastoma;Localized Resectable Neuroblastoma;Localized Unresectable Neuroblastoma;Regional Neuroblastoma;Stage 4S NeuroblastomaBiological: therapeutic immune globulin;Other: clinical observation;Drug: cyclophosphamide;Drug: prednisone;Procedure: magnetic resonance imaging;Other: laboratory biomarker analysis;Drug: Corticotropin-Releasing HormoneChildren's Oncology GroupNational Cancer Institute (NCI)Active, not recruitingN/A8 YearsAll53Phase 3United States;Australia;Canada;Netherlands;New Zealand;Puerto Rico;Switzerland