222. 一次性ネフローゼ症候群 Primary nephrotic syndrome Clinical trials / Disease details
臨床試験数 : 310 / 薬物数 : 295 - (DrugBank : 117) / 標的遺伝子数 : 63 - 標的パスウェイ数 : 194
Showing 1 to 10 of 310 diseases
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05667922 (ClinicalTrials.gov) | June 2023 | 7/12/2022 | Prognostic Model of TAC in the Treatment of MN | Development and Validation of a Prognostic Model for Idiopathic Membranous Nephropathy Treated With Tacrolimus Development and Validation of a Prognostic Model for Idiopathic Membranous NephropathyTreated With T ... | Idiopathic Membranous Nephropathy | Drug: Tacrolimus | Qianfoshan Hospital | NULL | Not yet recruiting | 18 Years | 75 Years | All | 50 | NULL | |
| 2 | NCT05667896 (ClinicalTrials.gov) | June 2023 | 7/12/2022 | Prognostic Model of GC/TAC in the Treatment of MN | Development and Validation of a Prognostic Model for Idiopathic Membranous Nephropathy Treated With Glucocorticoids Plus Tacrolimus Development and Validation of a Prognostic Model for Idiopathic Membranous NephropathyTreated With G ... | Idiopathic Membranous Nephropathy | Drug: glucocorticoid + tacrolimus | Qianfoshan Hospital | NULL | Not yet recruiting | 18 Years | 75 Years | All | 50 | NULL | |
| 3 | NCT05667883 (ClinicalTrials.gov) | June 2023 | 7/12/2022 | Prognostic Model of GC/CTX in the Treatment of MN | Development and Validation of a Prognostic Model for Idiopathic Membranous Nephropathy Treated With Glucocorticoids Plus Cytoxan Development and Validation of a Prognostic Model for Idiopathic Membranous NephropathyTreated With G ... | Idiopathic Membranous Nephropathy | Drug: glucocorticoid + cytoxan | Qianfoshan Hospital | NULL | Not yet recruiting | 18 Years | 75 Years | All | 50 | NULL | |
| 4 | NCT05667909 (ClinicalTrials.gov) | June 2023 | 7/12/2022 | Prognostic Model of Rituximab in the Treatment of MN | Development and Validation of a Prognostic Model for Idiopathic Membranous Nephropathy Treated With Rituximab Development and Validation of a Prognostic Model for Idiopathic Membranous NephropathyTreated With R ... | Idiopathic Membranous Nephropathy | Drug: Rituximab | Qianfoshan Hospital | NULL | Not yet recruiting | 18 Years | 75 Years | All | 50 | NULL | |
| 5 | NCT05707377 (ClinicalTrials.gov) | April 2023 | 23/1/2023 | A Study to Evaluate the Safety and Efficacy of Zanubrutinib in Participants With Primary Membranous Nephropathy A Study to Evaluate the Safety and Efficacy of Zanubrutinib in Participants With Primary Membranous ... | A Phase 2/3, Multicenter, Randomized, Active-Controlled, Open-label Study to Evaluate the Efficacy and Safety of Zanubrutinib in Patients With Primary Membranous Nephropathy A Phase 2/3, Multicenter, Randomized, Active-Controlled, Open-label Study to Evaluate the Efficacy a ... | Primary Membranous Nephropathy | Drug: Zanubrutinib;Drug: Tacrolimus | BeiGene | NULL | Not yet recruiting | 18 Years | 75 Years | All | 282 | Phase 2/Phase 3 | NULL |
| 6 | NCT05772871 (ClinicalTrials.gov) | March 30, 2023 | 24/2/2023 | The Efficacy and Safety of Prednisone Combined With Huaiqihuang Granule for Primary Nephrotic Syndrome in Children The Efficacy and Safety of Prednisone Combined With Huaiqihuang Granule for Primary Nephrotic Syndro ... | Compare the Efficacy and Safety of Prednisone Combined With Huaiqihuang Granule Versus Combined With Levamisole for Primary Nephrotic Syndrome in Children: A Prospective, Multi-center, Randomized, Double-blind, Non-inferiority Study Compare the Efficacy and Safety of Prednisone Combined With Huaiqihuang Granule Versus Combined With ... | Nephrotic Syndrome in Children | Drug: Huaiqihuang granule;Drug: Prednisone;Drug: Levamisole placebo;Drug: Levamisole;Drug: Huaiqihuang Granule placebo Drug: Huaiqihuang granule;Drug: Prednisone;Drug: Levamisoleplacebo;Drug: Levamisole;Drug: Huaiqihuan ... | Jianhua Zhou | LinkDoc Technology (Beijing) Co. Ltd. | Not yet recruiting | 18 Months | 18 Years | All | 402 | Phase 4 | NULL |
| 7 | NCT05732402 (ClinicalTrials.gov) | March 2023 | 8/2/2023 | An Open-label Study of Povetacicept (ALPN-303) in Autoimmune Kidney Diseases | An Open-Label, Multiple-Ascending Dose Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Different Dose Levels of Povetacicept in Subjects With Autoantibody-Associated Glomerular Diseases (RUBY-3) An Open-Label, Multiple-Ascending Dose Study to Assess the Safety, Efficacy, Pharmacokinetics, and P ... | Lupus Nephritis;Immunoglobulin A Nephropathy;Membranous Nephropathy | Drug: povetacicept | Alpine Immune Sciences, Inc. | NULL | Not yet recruiting | 18 Years | N/A | All | 42 | Phase 1 | NULL |
| 8 | NCT05668403 (ClinicalTrials.gov) | February 28, 2023 | 12/12/2022 | A Phase I Clinical Study of Recombinant Humanized Anti-CD20(B-lymphocyte Antigen CD20) Monoclonal Antibody Subcutaneous Injection in the Treatment of Primary Membranous Nephropathy A Phase I Clinical Study of Recombinant Humanized Anti-CD20(B-lymphocyte Antigen CD20) Monoclonal An ... | A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profiles and Preliminary Efficacy of Subcutaneous Injection of Recombinant Humanized Anti-CD20 Monoclonal Antibody in the Treatment of Primary Membranous Nephropathy A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic P ... | Primary Membranous Nephropathy | Drug: B007 | Shanghai Jiaolian Drug Research and Development Co., Ltd | Shanghai Pharmaceuticals Holding Co., Ltd | Not yet recruiting | 18 Years | 75 Years | All | 52 | Phase 1 | China |
| 9 | EUCTR2020-000384-23-DE (EUCTR) | 19/12/2022 | 17/05/2022 | A study to test BI 764198 in people with a type of kidney disease calledfocal segmental glomerulosclerosis. A study to test BI 764198 in people with a type of kidney disease calledfocal segmental glomeruloscl ... | A multicenter, randomized, double-blind, parallel group, placebo controlled study to assess the efficacy, safety, tolerability, pharmacokinetics and pharmacodynamics profile of BI 764198 administered orally once daily for 12 weeks in patients with focal segmental glomerulosclerosis - PoCP study in FSGS A multicenter, randomized, double-blind, parallel group, placebo controlled study to assess the effi ... | Focal segmental glomerulosclerosis MedDRA version: 21.1;Level: PT;Classification code 10067757;Term: Focal segmental glomerulosclerosis;System Organ Class: 10038359 - Renal and urinary disorders;Therapeutic area: Diseases [C] - Injuries, poisonings, and occupational diseases [C21] Focal segmental glomerulosclerosis MedDRA version: 21.1;Level: PT;Classification code 10067757;Term: ... | Product Code: BI 764198 INN or Proposed INN: None yet Other descriptive name: BI 764198 Product Code: BI 764198 INN or Proposed INN: None yet Other descriptive name: BI 764198 Product Code: BI 764198 INN or Proposed INN: None yet Other descriptive name: BI 764198 Product Code: BI 764198 INN or Proposed INN: Noneyet Other descriptive name: BI 764198 Product Code: BI ... | Boehringer Ingelheim Pharma GmbH & Co. KG | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 60 | Phase 2 | France;United States;Hungary;Belgium;Spain;Ireland;Australia;Germany;United Kingdom;Italy;China | ||
| 10 | EUCTR2020-005855-19-HU (EUCTR) | 03/11/2022 | 08/04/2022 | Evaluating oral BCX9930 in renal diseases | An Open-Label, Safety, Tolerability, and Proof-of-Concept Study of Oral BCX9930 Therapy in Subjects with Complement 3 Glomerulopathy, Immunoglobulin A Nephropathy, or Primary Membranous Nephropathy - RENEW An Open-Label, Safety, Tolerability, and Proof-of-Concept Study of Oral BCX9930 Therapy in Subjects ... | complement 3 glomerulopathyimmunoglobulin A nephropathyprimary membranous nephropathy MedDRA version: 20.0;Level: PT;Classification code 10021263;Term: IgA nephropathy;System Organ Class: 10038359 - Renal and urinary disorders MedDRA version: 21.1;Level: LLT;Classification code 10027170;Term: Membranous nephropathy;System Organ Class: 10038359 - Renal and urinary disorders MedDRA version: 20.0;Classification code 10077827;Term: C3 glomerulopathy;System Organ Class: 10038359 - Renal and urinary disorders;Therapeutic area: Body processes [G] - Immune system processes [G12] complement 3 glomerulopathyimmunoglobulin A nephropathyprimary membranous nephropathy MedDRA version ... | Product Name: BCX9930 Product Code: BCX9930 INN or Proposed INN: BCX9930 Other descriptive name: BCX9930 hydrochloride Product Name: BCX9930 Product Code: BCX9930 INN or Proposed INN: BCX9930 Other descriptive name: BCX9930 hydrochloride Product Name: BCX9930 Product Code: BCX9930 INN or Proposed INN: BCX9930 Other descriptive name: BCX993 ... | BioCryst Pharmaceuticals Inc | NULL | Not Recruiting | Female: yes Male: yes | 42 | Phase 2 | France;Hungary;Spain;Romania;Germany;United Kingdom;Italy |