222. 一次性ネフローゼ症候群 Primary nephrotic syndrome Clinical trials / Disease details
臨床試験数 : 310 / 薬物数 : 295 - (DrugBank : 117) / 標的遺伝子数 : 63 - 標的パスウェイ数 : 194
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2017-003022-32-PL (EUCTR) | 12/10/2019 | 20/08/2019 | An open, dose escalation study in patients with Primary Focal Segmental Glomerulosclerosis (FSGS - a type of glomerular disease causes scarring in the kidney) and Nephrotic Syndrom (collection of symptoms due to kidney damage) | An Open Label, Intra-Subject Dose Escalation Study of CCX140-B in Subjects with Primary Focal Segmental Glomerulosclerosis (FSGS) and Nephrotic Syndrome | Primary Focal Segmental Glomerulosclerosis (FSGS) MedDRA version: 21.1;Level: PT;Classification code 10067757;Term: Focal segmental glomerulosclerosis;System Organ Class: 10038359 - Renal and urinary disorders;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Product Code: CCX140-B INN or Proposed INN: not available yet | ChemoCentryx, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 13 | Phase 2 | United States;France;Canada;Poland;United Kingdom | ||
| 2 | EUCTR2017-003021-15-GB (EUCTR) | 23/10/2018 | 14/03/2018 | A study in which the safety and efficacy of CCX140-B is compared with placebo in patients with Focal Segmental Glomerulosclerosis | A Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects with Focal Segmental Glomerulosclerosis (FSGS) | Focal Segmental Glomerulosclerosis (FSGS) MedDRA version: 20.0;Level: PT;Classification code 10067757;Term: Focal segmental glomerulosclerosis;System Organ Class: 10038359 - Renal and urinary disorders;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Product Code: CCX140-B | ChemoCentryx, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 40 | Phase 2 | France;United States;Czech Republic;Canada;Poland;Australia;Germany;New Zealand;Italy;United Kingdom | ||
| 3 | NCT03703908 (ClinicalTrials.gov) | October 1, 2018 | 24/7/2018 | A Study of CCX140-B in Subjects With Primary FSGS and Nephrotic Syndrome | An Open Label, Intra-Subject Dose Escalation Study of CCX140-B in Subjects With Primary Focal Segmental Glomerulosclerosis (FSGS) and Nephrotic Syndrome | Focal Segmental Glomerulosclerosis | Drug: CCX140-B | ChemoCentryx | NULL | Recruiting | 18 Years | N/A | All | 13 | Phase 2 | United States |
| 4 | EUCTR2017-003021-15-IT (EUCTR) | 04/07/2018 | 10/11/2020 | A study to evaluate the efficacy og CCX140-B in patients with FSGS | A Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects with Focal Segmental Glomerulosclerosis (FSGS) - NA | Focal Segmental Glomerulosclerosis (FSGS) MedDRA version: 21.1;Level: PT;Classification code 10067757;Term: Focal segmental glomerulosclerosis;System Organ Class: 10038359 - Renal and urinary disorders;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Product Name: - Product Code: [CCX140-B] | CHEMOCENTRYX, INC. | NULL | Not Recruiting | Female: yes Male: yes | 40 | Phase 2 | United States;France;Czechia;Canada;Poland;Australia;Germany;United Kingdom;New Zealand;Italy | ||
| 5 | EUCTR2017-003021-15-PL (EUCTR) | 19/06/2018 | 18/05/2018 | A controlled study to evaluate the safety and efficacy of the study drug, CCX140-B, in subjects with Focal Segmental Glomerulosclerosis (a type of glomerular disease) | A Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects with Focal Segmental Glomerulosclerosis (FSGS) | Focal Segmental Glomerulosclerosis (FSGS) MedDRA version: 20.0;Level: PT;Classification code 10067757;Term: Focal segmental glomerulosclerosis;System Organ Class: 10038359 - Renal and urinary disorders;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Product Code: CCX140-B INN or Proposed INN: INN not available yet | ChemoCentryx, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 40 | Phase 2 | France;United States;Czech Republic;Canada;Poland;Australia;Germany;New Zealand;Italy;United Kingdom | ||
| 6 | EUCTR2017-003021-15-FR (EUCTR) | 18/05/2018 | 13/03/2018 | Study to determine the dose CCX140-B and to evaluate the its safety and efficacy of in Subjects with Focal Segmental Glomerulosclerosis (FSGS) | A Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects with Focal Segmental Glomerulosclerosis (FSGS) | Focal Segmental Glomerulosclerosis (FSGS) MedDRA version: 20.0;Level: PT;Classification code 10067757;Term: Focal segmental glomerulosclerosis;System Organ Class: 10038359 - Renal and urinary disorders;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Product Code: CCX140-B | ChemoCentryx, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 40 | Phase 2 | United States;France;Czech Republic;Canada;Poland;Australia;Germany;New Zealand;Italy;United Kingdom | ||
| 7 | NCT03536754 (ClinicalTrials.gov) | May 1, 2018 | 28/3/2018 | A Study of CCX140-B in Subjects With FSGS | A Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Focal Segmental Glomerulosclerosis (FSGS) | FSGS;Focal Segmental Glomerulosclerosis;Glomerulosclerosis | Other: Placebo;Drug: CCX140-B | ChemoCentryx | Medpace, Inc. | Completed | 18 Years | 75 Years | All | 46 | Phase 2 | United States;Australia;Canada;France;Italy;New Zealand;Poland;United Kingdom |