222. 一次性ネフローゼ症候群 Primary nephrotic syndrome Clinical trials / Disease details
臨床試験数 : 310 / 薬物数 : 295 - (DrugBank : 117) / 標的遺伝子数 : 63 - 標的パスウェイ数 : 194
Showing 1 to 10 of 45 diseases
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05667909 (ClinicalTrials.gov) | June 2023 | 7/12/2022 | Prognostic Model of Rituximab in the Treatment of MN | Development and Validation of a Prognostic Model for Idiopathic Membranous Nephropathy Treated With Rituximab Development and Validation of a Prognostic Model for Idiopathic Membranous Nephropathy Treated With ... | Idiopathic Membranous Nephropathy | Drug: Rituximab | Qianfoshan Hospital | NULL | Not yet recruiting | 18 Years | 75 Years | All | 50 | NULL | |
| 2 | NCT05532111 (ClinicalTrials.gov) | September 1, 2022 | 1/9/2022 | Efficacy and Safety of the Treatment of Primary Membranous Nephropathy: A Randomized Clinical Trial | Efficacy and Safety of Rituximab Combined With Tacrolimus in the Treatment of Intermediate-to-high Risk Primary Membranous Nephropathy: A Randomized Clinical Trial Efficacy and Safety of RituximabCombined With Tacrolimus in the Treatment of Intermediate-to-high Ri ... | Efficacy and Safety | Drug: Rituximab combined with tacrolimus induction + rituximab maintenance;Drug: Rituximab combined with tacrolimus induction + tacrolimus maintenance;Drug: Glucocorticoid combined with cyclophosphamide induction + maintenance Drug: Rituximabcombined with tacrolimus induction + rituximabmaintenance;Drug: Rituximabcombined wit ... | RenJi Hospital | NULL | Not yet recruiting | 18 Years | 75 Years | All | 60 | N/A | NULL |
| 3 | ChiCTR2200057381 | 2022-03-01 | 2022-03-10 | Efficacy and safety of low-dose rituximab in the treatment of membranous nephropathy | Efficacy and safety of low-dose rituximab in the treatment of membranous nephropathy | membranous nephropathy | rituximab group:rituximab;control:hormone combined with cyclophosphamide; | Peking University Third Hospital | NULL | Pending | 18 | 80 | Both | rituximab group:68;control:135; | N/A | China |
| 4 | EUCTR2021-004864-81-IT (EUCTR) | 17/12/2021 | 17/09/2021 | Proposta di studio per valutare l’efficacia di Obinutuzumab, un anticorpo anti-CD20, in pazienti con nefropatia membranosa intolleranti, resistenti o dipendenti alla terapia con Rituximab (studio ORION) Proposta di studio per valutare l’efficacia di Obinutuzumab, un anticorpo anti-CD20, in pazienti con ... | Proposta di studio per valutare l’efficacia di Obinutuzumab, un anticorpo anti-CD20, in pazienti con nefropatia membranosa intolleranti, resistenti o dipendenti alla terapia con Rituximab (studio ORION) - Obinutuzumab in primary MN Proposta di studio per valutare l’efficacia di Obinutuzumab, un anticorpo anti-CD20, in pazienti con ... | PRIMARY MEMBRANOUS NEPHROPATHY MedDRA version: 21.1;Level: LLT;Classification code 10027170;Term: Membranous nephropathy;System Organ Class: 100000004857;Therapeutic area: Diseases [C] - Male diseases of the urinary and reproductive systems [C12] PRIMARY MEMBRANOUS NEPHROPATHY MedDRA version: 21.1;Level: LLT;Classification code 10027170;Term: Me ... | Trade Name: GAZYVARO - 1000 MG - CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCINO - 1000MG/40ML - 1 FLACONCINO Product Name: GAZYVARO Product Code: [L01XC15] INN or Proposed INN: Obitunuzumab Trade Name: OMNIPAQUE - 300 MG I/ML SOLUZIONE INIETTABILE FLACONE IN POLIPROPILENE DA 50 ML Product Name: OMNIPAQUE Product Code: [Ioexolo] INN or Proposed INN: ioexolo Trade Name: GAZYVARO- 1000 MG - CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCIN ... | IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 20 | Phase 2 | Italy | ||
| 5 | ChiCTR2100049205 | 2021-08-01 | 2021-07-25 | A prospective randomized controlled multicenter clinical study on the treatment strategy of primary membranous nephropathy in the high-risk phase A prospective randomized controlled multicenter clinical study on the treatment strategy of primary ... | A prospective randomized controlled multicenter clinical study on the treatment strategy of primary membranous nephropathy in the high-risk phase A prospective randomized controlled multicenter clinical study on the treatment strategy of primary ... | Membranous nephropathy | Group B:Cyclophosphamide combined with glucocorticoids;Group C:Low-dose Cyclophosphamide, glucocorticoid combined with rituximab;Group A:Rituximab; Group B:Cyclophosphamidecombined with glucocorticoids;Group C:Low-dose Cyclophosphamide, glucocortic ... | Shanghai Dongfang Hospital | NULL | Recruiting | 18 | 75 | Both | Group B:30;Group C:30;Group A:30; | China | |
| 6 | NCT04743739 (ClinicalTrials.gov) | April 14, 2021 | 30/1/2021 | Rituximab Combined With Cyclosporine Versus Rituximab Alone in the Treatment of iMN | A Multicenter Randomized Controlled Trial of Rituximab Combined With Cyclosporine Versus Rituximab Alone in the Treatment of Idiopathic Membranous Nephropathy A Multicenter Randomized Controlled Trial of RituximabCombined With Cyclosporine Versus RituximabAlo ... | Idiopathic Membranous Nephropathy | Drug: Rituximab;Drug: cyclosporine | Peking Union Medical College Hospital | Beijing Tongren Hospital;Chinese Academy of Medical Sciences, Fuwai Hospital;The Luhe Teaching Hospital of the Capital Medical University;The Seventh Affiliated Hospital, Sun Yat-sen University;First Affiliated Hospital of Xinjiang Medical University;Nanyang Nanshi Hospital of Henan University;Shanghai Fosun Pharmaceutical Development Co, Ltd. Beijing Tongren Hospital;Chinese Academy of Medical Sciences, Fuwai Hospital;The Luhe Teaching Hospi ... | Recruiting | 18 Years | 80 Years | All | 126 | Phase 3 | China |
| 7 | NCT04745728 (ClinicalTrials.gov) | April 14, 2021 | 4/2/2021 | Different Immunosuppressive Treatment in iMN | Different Immunosuppressive Treatment in Idiopathic Membranous Nephropathy: a Prospective Cohort | Idiopathic Membranous Nephropathy | Drug: Prednisone;Drug: Cyclophosphamide;Drug: Rituximab | Peking Union Medical College Hospital | NULL | Recruiting | 18 Years | 80 Years | All | 200 | Phase 3 | China |
| 8 | ChiCTR2100042674 | 2021-01-18 | 2021-01-26 | Standard dose Rituximab for membranous nephropathy: a multi-center prospective cohort study | Standard dose Rituximab for membranous nephropathy: a multi-center prospective cohort study | syndrome disease | experimental group:RTX treatment; | Jiangsu Province People's Hospital | NULL | Recruiting | 18 | 75 | Male | experimental group:65; | Phase 4 | China |
| 9 | NCT03970577 (ClinicalTrials.gov) | July 29, 2020 | 15/4/2019 | RItuximab From the FIRst Episode of Idiopathic Nephrotic Syndrome | Rituximab From the First Episode of Minimal Change Nephrotic Syndrome for Preventing Relapse Risk in Adult Patients: a Multicenter Randomized Controlled Trial RituximabFrom the First Episode of Minimal Change Nephrotic Syndrome for Preventing Relapse Risk in ... | Minimal Change Nephrotic Syndrome (MCNS) | Drug: Rituximab;Drug: Prednisone | Assistance Publique - Hôpitaux de Paris | NULL | Recruiting | 18 Years | N/A | All | 148 | Phase 2 | France |
| 10 | ChiCTR2000032523 | 2020-06-01 | 2020-05-01 | Efficacy and safety of rituximab in the treatment of primary membranous nephropathy with type 2 diabetes mellitus: a single-center randomized controlled trial. Efficacy and safety of rituximabin the treatment of primary membranous nephropathy with type 2 diabe ... | Efficacy and safety of rituximab in the treatment of primary membranous nephropathy with type 2 diabetes mellitus: a single-center randomized controlled trial Efficacy and safety of rituximabin the treatment of primary membranous nephropathy with type 2 diabe ... | membranous nephropathy | experimental group:rituximab;control group:tacrolimus; | Xinqiao Hospital | NULL | Pending | 18 | 80 | Both | experimental group:40;control group:40; | Phase 4 | China |