To evaluate the efficacy and safety of tacrolimus in the treatment of children with Henoch Schonlein purpura nephritis To evaluate the efficacy and safety of tacrolimusin the treatment of children with Henoch Schonlein ...
A multicentre, randomized, prospective, observational study evaluating the efficacy and safety of tacrolimus in the treatment of Henoch Schonlein purpura nephritis in children at 24 weeks A multicentre, randomized, prospective, observational study evaluating the efficacy and safety of ta ...
Henoch Schonlein purpura nephritis
Experimental drug treatment group:Tacroximus capsule (trade name: Saifu X R), 0.1mg /kg/d, orally taken 1 hour before or 2-3 hours after meals twice a day for 24 weeks;Prednisone 1.5-2mg/kg/d was taken orally for 4 weeks and then changed to oral administration every other day for 4 weeks, gradually reducing the amount.;Control treatment group:Cyclophosphamide 8-10mg/ kg/d was given intravenously for 2 consecutive days, once every 2-4 weeks for 4 consecutive times, and once every 3 weeks for 2 consecutive times for 6 times in total.Prednisone 1.5-2mg/kg/d was taken orally with breakfast in the morning. ; Experimental drug treatment group:Tacroximus capsule (trade name: Saifu X R), 0.1mg /kg/d, orally ta ...
Shengjing Hospital of China Medical University
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Recruiting
Both
Experimental drug treatment group:156;Control treatment group:78;
Tacrolimus in Children With Henoch-Schönlein Purpura Nephritis
Off-label Use of Tacrolimus in Children With Henoch-Schönlein Purpura Nephritis: Effectiveness and Safety Off-label Use of Tacrolimusin Children With Henoch-Schönlein Purpura Nephritis: Effectiveness and Sa ...