226. 間質性膀胱炎（ハンナ型） Interstitial cystitis with Hunners ulcer Clinical trials / Disease details
臨床試験数 : 145 / 薬物数 : 156 - (DrugBank : 51) / 標的遺伝子数 : 64 - 標的パスウェイ数 : 146
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05141006 (ClinicalTrials.gov) | March 29, 2022 | 19/11/2021 | Study of BOTOX Injections to Assess Change in Disease Activity and Adverse Events in Adult Female Participants With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) | A Multicenter, Randomized, Double-blind, Placebo-Controlled, Parallel Arm Study to Assess the Safety and Efficacy of a Single Treatment of BOTOX, Followed by an Optional Open-Label Treatment With BOTOX, in Female Subjects With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) | Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) | Drug: BOTOX;Drug: Placebo for BOTOX | Allergan | NULL | Recruiting | 18 Years | 75 Years | Female | 80 | Phase 2 | United States;Canada |
| 2 | NCT05275647 (ClinicalTrials.gov) | May 18, 2021 | 13/1/2022 | Efficacy and Safety of Low Energy Shock Wave Plus BotulinumToxin A in Treating Patients With Interstitial Cystitis | Therapeutic Efficacy and Safety of Low Energy Shock Wave (LESW) Plus Botulinum Toxin A Instillation in Treatment of Patients With Interstitial Cystitis Refractory to Conventional Therapy - A Clinical and Immunohistochemistry Study | Interstitial Cystitis | Drug: BOTOX 100U in normal saline;Drug: Normal saline | Buddhist Tzu Chi General Hospital | Ministry of Science and Technology, Taiwan;Hualien Tzu Chi General Hospital | Recruiting | 20 Years | N/A | All | 75 | Phase 2 | Taiwan |
| 3 | NCT02247557 (ClinicalTrials.gov) | September 2014 | 15/9/2014 | Intravesical Instillation of Liposome Encapsulated Botulinum Toxin A (Lipotoxin) in Treatment of Interstitial Cystitis | Intravesical Instillation of Liposome Encapsulated Botulinum Toxin A (Lipotoxin) in Treatment of Interstitial Cystitis — a Randomized, Double-blind, Placebo-controlled, Prospective Study | Interstitial Cystitis | Drug: Liposome encapsulated BoNT-A;Drug: BOTOX 200U in normal saline;Drug: Normal saline | Buddhist Tzu Chi General Hospital | NULL | Completed | 20 Years | 80 Years | All | 90 | Phase 2 | Taiwan |
| 4 | EUCTR2007-005164-27-NL (EUCTR) | 22/02/2008 | 17/10/2007 | Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/Interstitial Cystitis | Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/Interstitial Cystitis | Interstitial Cystitis (IC) is a syndrome characterized by bladder pain associated with urgency, frequency, nocturia, dysuria and sterile urine. The patho-physiology remains largely unclear. No universally, effective, treatment exists. Botulinum toxin-A (BTX-A) inhibits the release of acetylcholine at the presynaptic cholinergic junction resulting in temporally muscle relaxation and bladder desensitisation. We explore the effects of intravesical injections with BTX-A in the treatment of IC. | Trade Name: Botox | research office urology VUmc | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 12 | Netherlands | |||
| 5 | NCT00194610 (ClinicalTrials.gov) | May 2004 | 13/9/2005 | Botox as a Treatment for Interstitial Cystitis in Women | Botox (Botulinum Toxin A) as a Treatment for Interstitial Cystitis in Women: A Randomized Placebo Controlled Trial | Painful Bladder Syndrome;Interstitial Cystitis | Drug: Botox;Other: normal saline | University of Washington | Paul G. Allen Family Foundation | Completed | 18 Years | N/A | Female | 20 | Phase 4 | United States |