228. 閉塞性細気管支炎 Bronchiolitis obliterans Clinical trials / Disease details


臨床試験数 : 97 薬物数 : 118 - (DrugBank : 32) / 標的遺伝子数 : 33 - 標的パスウェイ数 : 156

  
8 trials found
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PhaseCountries
1NCT03315741
(ClinicalTrials.gov)
March 1, 20185/10/2017The Safety and Tolerability of Pirfenidone for BOS After HCTThe Safety and Tolerability of Pirfenidone for Bronchiolitis Obliterans Syndrome After Hematopoietic Cell TransplantationBronchiolitis Obliterans;Graft Vs Host DiseaseDrug: Pirfenidone 267 MG [Esbriet]Stanford UniversityGenentech, Inc.Completed18 YearsN/AAll30Phase 1United States
2EUCTR2014-002022-12-SE
(EUCTR)
06/08/201515/10/2014European Trial of Pirfenidone in BOS (EPOS).A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s).
MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000004855;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
Trade Name: Esbriet
Product Name: Pirfenidone
INN or Proposed INN: PIRFENIDONE
Other descriptive name: 5-Methyl-1-Phenyl-2-1-(H)-Pyridone
Clinical Trials Unit, RigshospitaletNULLNot RecruitingFemale: yes
Male: yes
80Phase 2Belgium;Denmark;Netherlands;Germany;United Kingdom;Sweden
3EUCTR2014-002022-12-NL
(EUCTR)
13/05/201503/11/2014European Trial of Pirfenidone in BOS (EPOS).A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s).
MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000004855;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
Trade Name: Esbriet
Product Name: Pirfenidone
INN or Proposed INN: PIRFENIDONE
Other descriptive name: 5-Methyl-1-Phenyl-2-1-(H)-Pyridone
Clinical Trials Unit, RigshospitaletNULLNot RecruitingFemale: yes
Male: yes
80Phase 2Belgium;Denmark;Germany;Netherlands;United Kingdom;Sweden
4NCT02262299
(ClinicalTrials.gov)
May 201521/9/2014European Trial of Pirfenidone in BOS, A European Multi-center StudyA European Multi-center, Randomised, Double-blind Trial of Pirfenidone in Bronchiolitis-obliterans-syndrome Grade 1-3 in Lung Transplant RecipientsDisorder Related to Lung Transplantation;CLAD, Bronchiolitis ObliteransDrug: Pirfenidone;Drug: PlaceboRigshospitalet, DenmarkNULLCompleted18 YearsN/AAll90Phase 2/Phase 3Belgium;Denmark;Germany;Netherlands;Norway;Sweden;United Kingdom
5EUCTR2014-002022-12-BE
(EUCTR)
10/03/201515/10/2014European Trial of Pirfenidone in BOS (EPOS).A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s).
MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000015490;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
Trade Name: Esbriet
Product Name: Pirfenidone
INN or Proposed INN: PIRFENIDONE
Other descriptive name: 5-Methyl-1-Phenyl-2-1-(H)-Pyridone
Clinical Trials Unit, RigshospitaletNULLNot RecruitingFemale: yes
Male: yes
80Phase 2Belgium;Denmark;Netherlands;Germany;United Kingdom;Sweden
6EUCTR2014-002022-12-GB
(EUCTR)
06/01/201515/10/2014European Trial of Pirfenidone in BOS (EPOS).A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s).
MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000004855 ;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
Trade Name: Esbriet
Product Name: Pirfenidone
INN or Proposed INN: PIRFENIDONE
Other descriptive name: 5-Methyl-1-Phenyl-2-1-(H)-Pyridone
Clinical Trials Unit, RigshospitaletNULLAuthorised-recruitment may be ongoing or finished Female: yes
Male: yes
90 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): noBelgium;Denmark;Netherlands;Germany;United Kingdom;Sweden
7EUCTR2014-002022-12-DE
(EUCTR)
30/12/201421/10/2014European Trial of Pirfenidone in BOS (EPOS).A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s).
MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000004855;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
Trade Name: Esbriet
Product Name: Pirfenidone
INN or Proposed INN: PIRFENIDONE
Other descriptive name: 5-Methyl-1-Phenyl-2-1-(H)-Pyridone
Clinical Trials Unit, RigshospitaletNULLNot RecruitingFemale: yes
Male: yes
80Phase 2Belgium;Denmark;Netherlands;Germany;United Kingdom;Sweden
8EUCTR2014-002022-12-DK
(EUCTR)
15/12/201404/11/2014European Trial of Pirfenidone in BOS (EPOS).A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s).
MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000004855;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
Trade Name: Esbriet
Product Name: Pirfenidone
INN or Proposed INN: PIRFENIDONE
Other descriptive name: 5-Methyl-1-Phenyl-2-1-(H)-Pyridone
Clinical Trials Unit, RigshospitaletNULLNot RecruitingFemale: yes
Male: yes
90Phase 2Belgium;Denmark;Netherlands;Germany;United Kingdom;Sweden