229. 肺胞蛋白症（自己免疫性又は先天性） Autoimmune pulmonary alveolar proteinosis Clinical trials / Disease details

臨床試験数 : 44 / 薬物数 : 22 - (DrugBank : 7) / 標的遺伝子数 : 3 - 標的パスウェイ数 : 14

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2020-001263-85-ES (EUCTR)	25/04/2022	02/02/2022	A clinical trial where patients with the lung disease autoimmune pulmonary alveolar proteinosiswill ...	A randomized, double-blind, placebo-controlled clinical trial of once-daily inhaled molgramostim neb ...	Autoimmune Pulmonary Alveolar Proteinosis(aPAP) MedDRA version: 21.1;Level: LLT;Classification code ...	Product Name: Molgramostim 300 µg nebulizer solution INN or Proposed INN: Molgramostim	Savara ApS	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	160	Phase 3	United States;Portugal;Greece;Spain;Ireland;Turkey;Russian Federation;United Kingdom;Italy;France;Ca ...
2	EUCTR2020-001263-85-NL (EUCTR)	19/07/2021	08/10/2020	A clinical trial where patients with the lung disease autoimmunePulmonary Alveolar Proteinosis will ...	A randomized, double-blind, placebo-controlled clinical trial of once-daily inhaled molgramostim neb ...	Autoimmune Pulmonary Alveolar Proteinosis(aPAP) MedDRA version: 21.1;Level: LLT;Classification code ...	Product Name: Molgramostim 300 µg nebulizer solution INN or Proposed INN: Molgramostim	Savara ApS	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	160	Phase 3	United States;Ireland;Turkey;United Kingdom;Italy;France;Canada;Belgium;Poland;Romania;Netherlands;G ...
3	NCT04811274 (ClinicalTrials.gov)	June 7, 2021	19/3/2021	Macrophages, GM-CSF and MARS Proteinosis	Study of Macrophage Function and of the GM-CSF Signaling Pathway in Alveolar Proteinosis by Mutation ...	Pulmonary Alveolar Proteinosis (PAP);MARS;Genetic Mutation	Biological: Blood collection;Biological: Bronchoalveolar lavage fluid collection	Assistance Publique - Hôpitaux de Paris	NULL	Recruiting	N/A	17 Years	All	20		France
4	NCT04544293 (ClinicalTrials.gov)	May 10, 2021	3/9/2020	Clinical Trial of Inhaled Molgramostim Nebulizer Solution in Autoimmune Pulmonary Alveolar Proteinos ...	A Randomized, Double-blind, Placebo-controlled Clinical Trial of Once-daily Inhaled Molgramostim Neb ...	Autoimmune Pulmonary Alveolar Proteinosis	Drug: Molgramostim;Drug: Placebo	Savara Inc.	NULL	Recruiting	18 Years	N/A	All	160	Phase 3	United States;Australia;Belgium;Canada;France;Germany;Greece;Ireland;Italy;Japan;Korea, Republic of; ...
5	EUCTR2020-001263-85-RO (EUCTR)	11/03/2021	19/05/2022	A clinical trial where patients with the lung disease autoimmunePulmonary Alveolar Proteinosis will ...	A randomized, double-blind, placebo-controlled clinical trial of once-daily inhaled molgramostim neb ...	Autoimmune Pulmonary Alveolar Proteinosis(aPAP) MedDRA version: 21.1;Level: LLT;Classification code ...	Product Name: Molgramostim 300 µg nebulizer solution INN or Proposed INN: Molgramostim	Savara ApS	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	160	Phase 3	United States;Spain;Ireland;Turkey;United Kingdom;Italy;France;Canada;Poland;Belgium;Romania;Netherl ...
6	EUCTR2020-001263-85-BE (EUCTR)	08/03/2021	04/12/2020	A clinical trial where patients with the lung disease autoimmunePulmonary Alveolar Proteinosis will ...	A randomized, double-blind, placebo-controlled clinical trial of once-daily inhaled molgramostim neb ...	Autoimmune Pulmonary Alveolar Proteinosis(aPAP) MedDRA version: 21.1;Level: LLT;Classification code ...	Product Name: Molgramostim 300 µg nebulizer solution INN or Proposed INN: Molgramostim	Savara ApS	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	160	Phase 3	United States;Ireland;Turkey;United Kingdom;Italy;France;Canada;Belgium;Poland;Romania;Germany;Nethe ...
7	EUCTR2020-001263-85-IE (EUCTR)	08/02/2021	08/10/2020	A clinical trial where patients with the lung disease autoimmunePulmonary Alveolar Proteinosis will ...	A randomized, double-blind, placebo-controlled clinical trial of once-daily inhaled molgramostim neb ...	Autoimmune Pulmonary Alveolar Proteinosis(aPAP) MedDRA version: 21.1;Level: LLT;Classification code ...	Product Name: Molgramostim 300 µg nebulizer solution INN or Proposed INN: Molgramostim	Savara ApS	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	160	Phase 3	United States;Ireland;Turkey;Italy;United Kingdom;France;Canada;Belgium;Poland;Romania;Germany;Nethe ...
8	EUCTR2020-001263-85-DE (EUCTR)	27/01/2021	16/10/2020	A clinical trial where patients with the lung disease autoimmunePulmonary Alveolar Proteinosis will ...	A randomized, double-blind, placebo-controlled clinical trial of once-daily inhaled molgramostim neb ...	Autoimmune Pulmonary Alveolar Proteinosis(aPAP) MedDRA version: 21.1;Level: LLT;Classification code ...	Product Name: Molgramostim 300 µg nebulizer solution INN or Proposed INN: Molgramostim	Savara ApS	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	160	Phase 3	Portugal;United States;Greece;Spain;Ireland;Turkey;United Kingdom;Italy;France;Canada;Belgium;Poland ...
9	EUCTR2020-001263-85-PL (EUCTR)	16/12/2020	19/11/2020	A clinical trial where patients with the lung disease autoimmunePulmonary Alveolar Proteinosis will ...	A randomized, double-blind, placebo-controlled clinical trial of once-daily inhaled molgramostim neb ...	Autoimmune Pulmonary Alveolar Proteinosis(aPAP) MedDRA version: 21.1;Level: LLT;Classification code ...	Product Name: Molgramostim 300 µg nebulizer solution INN or Proposed INN: Molgramostim	Savara ApS	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	160	Phase 3	Portugal;United States;Greece;Spain;Ireland;Turkey;United Kingdom;Italy;France;Canada;Belgium;Poland ...
10	EUCTR2020-001263-85-IT (EUCTR)	18/11/2020	24/05/2021	A clinical trial where patients with the lung disease autoimmune Pulmonary Alveolar Proteinosiswill ...	A randomized, double-blind, placebo-controlled clinical trial of once-daily inhaled molgramostim neb ...	Autoimmune Pulmonary Alveolar Proteinosis(aPAP) MedDRA version: 21.1;Level: LLT;Classification code ...	Product Name: Molgramostim 300 µg nebulizer solution Product Code: [na] INN or Proposed INN: 00201600	SAVARA APS	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	160	Phase 3	United States;Korea, Democratic People's Republic of;Ireland;Turkey;United Kingdom;Italy;France;Cana ...

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