DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
251. 尿素サイクル異常症
Urea cycle disorder
Clinical trials
/
Disease details
臨床試験数
:
54
/
薬物数
:
61
- (
DrugBank
:
15
) /
標的遺伝子数
:
3
-
標的パスウェイ数
:
28
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TrialID
Date_
enrollment
Date_
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Public_title
Scientific_title
Condition
Intervention
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sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
Phase
Countries
1
NCT03181828
(
ClinicalTrials.gov
)
March 24, 2017
1/6/2017
Manipulating the Gut Microbiome Study
Manipulating the Gut Microbiome Study
Urea Cycle Disorder
Drug:
Acetohydroxamic Acid
Oral Tablet [Lithostat]
Nicholas Ah Mew
NULL
Terminated
18 Years
60 Years
All
4
Phase 1/Phase 2
United States
2
NCT02670889
(
ClinicalTrials.gov
)
November 2016
14/1/2016
Urease Inhibitor Drug Treatment for Urea Cycle Disorders
Manipulating the Gut Microbiome in Urea Cycle Disorders
Ornithine Transcarbamylase Deficiency;Argininosuccinate Synthetase Deficiency (Citrullinemia);Argininosuccinic Acid Lyase Deficiency (Argininosuccinic Aciduria);Carbamyl-Phosphate Synthase I Deficiency
Ornithine Transcarbamylase Deficiency;Argininosuccinate Synthetase Deficiency (Citrullinemia);Argini ...
Drug:
Acetohydroxamic Acid
;Drug:
Isotopic Intravenous [13C]-Urea
Nicholas Ah Mew
Data Management and Coordinating Center (DMCC);Children's Hospital of Philadelphia
Not yet recruiting
18 Years
60 Years
Both
16
Phase 1/Phase 2
NULL