271. 強直性脊椎炎 Ankylosing spondylitis Clinical trials / Disease details
臨床試験数 : 574 / 薬物数 : 359 - (DrugBank : 68) / 標的遺伝子数 : 41 - 標的パスウェイ数 : 146
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03473665 (ClinicalTrials.gov) | March 1, 2018 | 13/3/2018 | Non-Steroidal Anti-inflammatory Drugs in Axial Spondyloarthritis | Non-Steroidal Anti-inflammatory Drugs in Axial Spondyloarthritis: a Pilot Study | Ankylosing Spondylitis;Axial Spondyloarthritis | Drug: Indomethacin;Drug: Diclofenac;Drug: Meloxicam;Drug: Celecoxib | Columbia University | NULL | Terminated | 18 Years | N/A | All | 9 | Phase 4 | United States |
| 2 | ChiCTR-ONRC-10000858 | 2010-05-10 | 2010-04-28 | Research on safety tolerance and pharmacokinetics of oral muti-dose Thalidomide | Research on safety tolerance and pharmacokinetics of oral muti-dose Thalidomide | Ankylosing Spondylitis | Group A:Muti-dose Thalidomide;GroupB:Muti-dose Thalidomide and Diclofenac sodium enteric-coated tablets ; | Chinese PLA General Hospital | NULL | Completed | 18 | 45 | Both | Group A:15;GroupB:12; | I (Phase 1 study) | China |
| 3 | NCT00762463 (ClinicalTrials.gov) | July 2009 | 29/9/2008 | Study Of Celecoxib Or Diclofenac For Efficacy and Safety In Chinese Patients With Ankylosing Spondylitis | A 6-Week, Randomized, Double-Blind, Parallel-Group Study To Evaluate The Symptomatic Effects And Safety Of Celecoxib 200mg QD Compared To Diclofenac 75mg SR QD In Chinese Patients With Ankylosing Spondylitis, With 6-Week Extension Phase Treatment On Celecoxib 400 Mg QD Or Maintaining Double-Blind Phase Therapy | Ankylosing Spondylitis | Drug: Celecoxib;Drug: Diclofenac SR | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | NULL | Completed | 18 Years | 65 Years | All | 240 | Phase 3 | China |
| 4 | NCT00766402 (ClinicalTrials.gov) | October 2008 | 3/10/2008 | An Efficacy and Safety Study of Tramadol/Acetaminophen Versus Diclofenac in the Treatment of Pain in Participants With Ankylosing Spondylitis Receiving Stable Treatment of Disease Modifying Anti-rheumatic Drugs (DMARDs) | A Study to Evaluate the Clinical Benefits of Tramadol/Acetaminophen (Ultracet®) vs. Diclofenac (Voltaren®) in the Treatment of Pain in Patients With Ankylosing Spondylitis Receiving Stable Treatment of Disease Modifying Anti-rheumatic Drugs (DMARDs) | Spondylitis, Ankylosing;Pain | Drug: Tramadol /acetaminophen;Drug: Diclofenac | Johnson & Johnson Taiwan Ltd | NULL | Terminated | 18 Years | 70 Years | Both | 8 | Phase 4 | NULL |
| 5 | NCT00648141 (ClinicalTrials.gov) | January 2003 | 28/3/2008 | Safety and Efficacy of Celecoxib Versus Diclofenac in the Treatment of Ankylosing Spondylitis | A 12-Week Symptomatic Effect Evaluation to Compare Celecoxib 200 mg QD, Celecoxib 200 mg BID and Diclofenac 75 mg SR BID in Patients With Ankylosing Spondylitis | Spondylitis, Ankylosing | Drug: Celecoxib;Drug: Diclofenac | Pfizer | NULL | Completed | 18 Years | 75 Years | Both | 458 | Phase 3 | Germany |
| 6 | NCT02528201 (ClinicalTrials.gov) | September 2002 | 18/6/2015 | A Study Of Celecoxib Versus Diclofenac In Patients With Ankylosing Spondylitis | A Twelve Week, Randomized, Double Blind Parallel Group Study Of Two Doses Of Celecoxib Compared To Diclofenac In Patients With Ankylosing Spondylitis | Ankylosing Spondylitis | Drug: Celecoxib 200 milligrams;Drug: Celecoxib 400 milligrams;Drug: diclofenac 50 milligrams | Pfizer | NULL | Completed | 18 Years | 75 Years | Both | 330 | Phase 4 | Norway |