28. 全身性アミロイドーシス Systemic amyloidosis Clinical trials / Disease details

臨床試験数 : 267 /  薬物数 : 241 - (DrugBank : 77) / 標的遺伝子数 : 68 - 標的パスウェイ数 : 180

  
3 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT05066607
(ClinicalTrials.gov)		February 11, 202224/8/2021Isatuximab Plus Pomalidomide and Dexamethasone Association for Patients With AL Amyloidosis Not in VGPR or Better After Any Previous TherapyA Phase 2, Open Label, Multicenter, Single-stage Study to Evaluate the Efficacy of Isatuximab Plus Pomalidomide and Dexamethasone (IPd), in Patients With AL Amyloidosis Not in VGPR or Better After Any Previous TherapyAL AmyloidosisDrug: IsatuximabIntergroupe Francophone du MyelomeSanofi;Bristol-Myers SquibbRecruiting18 YearsN/AAll46Phase 2France
2NCT04754945
(ClinicalTrials.gov)		April 28, 20219/2/2021Isatuximab as Upfront Therapy for the Treatment of High Risk AL AmyloidosisSlow-Go Strategy for High Risk AL Amyloidosis: Isatuximab for Upfront TherapyAL AmyloidosisDrug: Bortezomib;Drug: Cyclophosphamide;Drug: Dexamethasone;Biological: IsatuximabEmory UniversitySanofi;National Cancer Institute (NCI)Recruiting18 YearsN/AAll25Phase 1United States
3NCT03499808
(ClinicalTrials.gov)		March 8, 20189/4/2018S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary AmyloidosisA Phase II Study of Isatuximab (SAR650984) (NSC-795145) for Patients With Previously Treated AL AmyloidosisAmorphous, Eosinophilic, and Acellular Deposit;Constipation;Diarrhea;Early Satiety;Gastrointestinal Hemorrhage;Hepatomegaly;Lymphadenopathy;Macroglossia;Nausea;Primary Systemic Amyloidosis;Purpura;Recurrent Primary Amyloidosis;Refractory Primary AmyloidosisBiological: Isatuximab;Other: Laboratory Biomarker AnalysisSouthwest Oncology GroupNational Cancer Institute (NCI)Active, not recruiting18 YearsN/AAll43Phase 2United States