28. 全身性アミロイドーシス Systemic amyloidosis Clinical trials / Disease details

臨床試験数 : 267 / 薬物数 : 241 - (DrugBank : 77) / 標的遺伝子数 : 68 - 標的パスウェイ数 : 180

4 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05451771 (ClinicalTrials.gov)	October 26, 2022	6/7/2022	Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis	An Open-label Phase I/II Trial of Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Sy ...	AL Amyloidosis	Drug: Venetoclax Oral Tablet, 200 mg;Device: FISH assay;Drug: Venetoclax Oral Tablet, 400 mg;Drug: Dex ...	Rajshekhar Chakraborty, MD	Genentech, Inc.	Recruiting	18 Years	N/A	All	53	Phase 1/Phase 2	United States
2	NCT03618537 (ClinicalTrials.gov)	August 2, 2018	2/8/2018	Ixazomib Maintenance Study in Patients With AL Amyloidosis	IxazomibMaintenance Following Initial Therapy in Patients With Immunoglobulin Light Chain (AL) Amylo ...	AL Amyloidosis	Drug: Ixazomib;Drug: Dexamethasone	Memorial Sloan Kettering Cancer Center	Tufts Medical Center;Vanderbilt University Medical Center	Recruiting	18 Years	N/A	All	47	Phase 2	United States
3	NCT03283917 (ClinicalTrials.gov)	February 7, 2018	13/9/2017	Daratumumab, Ixazomib, and Dexamethasone in AL Amyloidosis	A Safety Study of Daratumumab, Ixazomib, and Dexamethasone in AL Amyloidosis	Newly Diagnosed Primary Amyloidosis;Recurrent Primary Amyloidosis;Refractory Primary Amyloidosis	Biological: Daratumumab;Drug: Dexamethasone;Drug: Ixazomib	M.D. Anderson Cancer Center	Janssen Pharmaceuticals;Takeda	Recruiting	18 Years	N/A	All	20	Phase 1	United States
4	NCT03236792 (ClinicalTrials.gov)	June 12, 2017	20/7/2017	Ixazomib In Combination With Cyclophosphamide And Dexamethasone for Newly Diagnosed AL Amyloidosis	Phase 1/2 Study Of IxazomibIn Combination With Cyclophosphamide And Dexamethasone In Patients With N ...	AL Amyloidosis	Drug: Ixazomib;Drug: Cyclophosphamide;Drug: Dexamethasone	Icahn School of Medicine at Mount Sinai	Millennium Pharmaceuticals, Inc.	Completed	18 Years	N/A	All	28	Phase 1/Phase 2	United States

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