296. 胆道閉鎖症 Biliary atresia Clinical trials / Disease details
臨床試験数 : 71 / 薬物数 : 70 - (DrugBank : 39) / 標的遺伝子数 : 35 - 標的パスウェイ数 : 60
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ChiCTR2200059705 | 2022-05-01 | 2022-05-08 | Machine Learning Based on Sonographic Gallbladder Images in Prenatal Diagnosis of Biliary Atresia | Machine Learning Based on Sonographic Gallbladder Images in Prenatal Diagnosis of Biliary Atresia | Biliary atresia | Gold Standard:Surgical exploration, puncture biopsy, intraoperative cholangiography, or percutaneous cholecystography ;Index test:Intelligent prenatally diagnostic system based on sonographic gallbladder images; | Shengjing Hospital of China Medical University | NULL | Pending | Female | Target condition:2000;Difficult condition:0 | China | |||
| 2 | ChiCTR2200055459 | 2022-02-01 | 2022-01-10 | Establishment of a diagnostic model of biliary atresia ultrasound combined with MMP-7: a multicenter diagnostic accuracy study | Establishment of a diagnostic model of biliary atresia ultrasound combined with MMP-7: a multicenter diagnostic accuracy study | Biliary atresia | Gold Standard:Biliary tract exploration and liver pathology.;Index test:MMP-7, ultrasound, MMP-7 and ultrasound combined diagnostic model.; | Pediatric Hospital Affiliated to Fudan University | NULL | Recruiting | Both | Target condition:150;Difficult condition:150 | China | |||
| 3 | ChiCTR2100053800 | 2021-12-13 | 2021-11-29 | Multimodal Magnetic Resonance Imaging for Evaluating the Developmental State of Bile Ducts and the Degree of Hepatic Fibrosis in Children with Biliary Atresia | Multimodal Magnetic Resonance Imaging for Evaluating the Developmental State of Bile Ducts and the Degree of Hepatic Fibrosis in Children with Biliary Atresia | Biliary Atresia | Gold Standard:Intraoperative cholangiography is often considered the diagnostic gold standard for biliary atresia. Blood biochemical examination is used as a reference standard for evaluating liver fibrosis.;Index test:Multimodal Magnetic Resonance Imaging; | Children's Hospital of Chongqing Medical University | NULL | Recruiting | Both | Target condition:100;Difficult condition:0 | China | |||
| 4 | ChiCTR2100044533 | 2021-06-01 | 2021-03-23 | Multicenter study of non-invasive diagnostic scoring system for biliary atresia | Multicenter study of non-invasive diagnostic scoring system for biliary atresia | Biliary atresia | Gold Standard:Intraoperative cholangiography;Index test:Non-invasive diagnostic scoring system for biliary atresia (Biochemicaltests, blood routine, CRP, blood ammonia, AFP, hepatobiliary B ultrasound); | Children's Hospital Affiliated to Zhejiang University Medical College | NULL | Recruiting | Both | Target condition:200;Difficult condition:0 | China | |||
| 5 | ChiCTR2000032983 | 2020-08-01 | 2020-05-17 | Development of Biomarkers for Biliary Atresia and Establishment of Artificial Intelligence Diagnostic Model | Development of Biomarkers for Biliary Atresia and Establishment of Artificial Intelligence Diagnostic Model | Biliary atresia | Gold Standard:Cholangiography combined with liver biopsy;Index test:MMP7;bile acid profile; | Children's Hospital of Fudan University | NULL | Recruiting | Both | Target condition:600;Difficult condition:600 | China | |||
| 6 | ChiCTR2000034127 | 2020-07-20 | 2020-06-25 | Application of MMP-7 in early diagnosis of neonatal biliary atresia | Application of MMP-7 in early diagnosis of neonatal biliary atresia | Biliary atresia disease | Gold Standard:Laparoscopic cholangiography;Index test:Serum MMP-7; | Department of Pediatric Surgery, Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology | NULL | Pending | 0.1 | Both | Target condition:300;Difficult condition:0 | China | ||
| 7 | ChiCTR1800019866 | 2019-01-01 | 2018-12-02 | Development and validation of novel diagnostic model for biliary atresia | Development and validation of novel diagnostic model for biliary atresia: a multicenter diagnostic test | biliary atresia | Gold Standard:cholangiography combined with liver biopsy;Index test:Nomogram; | Children's Hospital of Fudan University | NULL | Pending | Both | Target condition:1000;Difficult condition:200 | China | |||
| 8 | ChiCTR1800017428 | 2018-08-15 | 2018-07-30 | Machine learning based on the gallbladder morphology for screening biliary atresia among infants with conjugated hyperbilirubinemia | Machine learning based on the gallbladder morphology for screening biliary atresia among infants with conjugated hyperbilirubinemia | Biliary atresia | Gold Standard:Surgical exploration, puncture biopsy, intraoperative cholangiography or percutaneous cholecystography;Index test:machine learning based on the gallbladder morphology; | Department of Medical Ultrasonics, the First Affiliated Hospital of Sun Yat-sen University | NULL | Pending | Both | Target condition:500;Difficult condition:100 | China | |||
| 9 | ChiCTR-DPD-15005847 | 2014-11-19 | 2015-01-19 | Evidence-based guideline of diagnosis and treatment of biliary atresia | Evidence-based guideline of diagnosis and treatment of biliary atresia | biliary atresia | Gold Standard:;Index test:; | Children's Hospital of Fudan University | NULL | Pending | 0 | 18 | Both | Target condition:0;Difficult condition:0 | I (Phase 1 study) | China |