299. 嚢胞性線維症 Cystic fibrosis Clinical trials / Disease details


臨床試験数 : 1,695 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

  
3 trials found
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PhaseCountries
1NCT02323100
(ClinicalTrials.gov)
December 2, 201818/12/2014Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis)A Double Blind, Placebo Controlled, Dose Escalation Trial of Glycerol Phenylbutyrate Corrector Therapy for Cystic FibrosisCystic FibrosisDrug: Ravicti low dose;Drug: Ravicti high dose;Drug: PlaceboNational Jewish HealthUniversity of Alabama at Birmingham;Children's Hospital of Philadelphia;Johns Hopkins University;Horizon Pharma Ireland, Ltd., Dublin IrelandRecruiting18 YearsN/AAll36Phase 1/Phase 2United States
2NCT00590538
(ClinicalTrials.gov)
February 200327/12/2007Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygotes (for Cystic Fibrosis)A Pilot Trial of Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygous Cystic Fibrosis PatientsCystic FibrosisDrug: Sodium 4-Phenylbutyrate;Drug: Genistein (Unconjugated Isoflavones 100);Drug: PlaceboChildren's Hospital of PhiladelphiaCystic Fibrosis Foundation TherapeuticsTerminated18 YearsN/AAll9Phase 1/Phase 2United States
3NCT00016744
(ClinicalTrials.gov)
September 200131/5/2001Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous(for Cystic Fibrosis)A Pilot Trial of Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous Cystic Fibrosis PatientsCystic FibrosisDrug: Sodium 4-Phenylbutyrate (4PBA);Drug: Unconjugated Isoflavones 100 (PTI G-4660, 87% Genistein);Drug: PlaceboChildren's Hospital of PhiladelphiaCystic Fibrosis Foundation Therapeutics;National Center for Research Resources (NCRR)Completed18 YearsN/ABoth12Phase 1/Phase 2United States